Five highly informative X-chromosomal STRs in Koreans
Authors
Kyoung-Jin Shin ; Byung-Ki Kwon ; Chong-Youl Kim ; Jong-Hoon Choi ; Gil-Ro Han ; Hwan Young Lee ; Ukhee Chung ; Myung Jin Park ; Ji-Eun Yoo ; Sang-Seob Lee
Citation
INTERNATIONAL JOURNAL OF LEGAL MEDICINE, Vol.118(1) : 37-40, 2004
Chromosomes, Human, X/genetics* ; Female ; Forensic Medicine ; Gene Frequency ; Genetics, Population* ; Humans ; Korea ; Male ; Polymorphism, Genetic* ; Tandem Repeat Sequences*
Keywords
STR ; X-chromosome ; Korea
Abstract
The five X-chromosomal short tandem repeats (STRs) GATA172D05, HPRTB, DXS8377, DXS101 and HumARA were analyzed in 150 males and 150 females from Korea. Markers were amplified in a quadruplex and a monoplex PCR reaction with fluorescently labeled primers. For accurate and reproducible STR typing, sequenced allelic ladders were constructed and a Genotyper macro was programmed. Some differences were found on comparing the allele frequencies of Koreans with those of other populations in DXS8377, DXS101 and HumARA. The forensic efficiency parameters showed that the five X-linked STRs are highly informative for forensic application in Koreans.