Cited 51 times in
The course of patients with lacunar infarcts and a parent arterial lesion: similarities to large artery vs small artery disease
DC Field | Value | Language |
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dc.contributor.author | 이재혁 | - |
dc.contributor.author | 이필휴 | - |
dc.date.accessioned | 2015-07-14T16:34:20Z | - |
dc.date.available | 2015-07-14T16:34:20Z | - |
dc.date.issued | 2004 | - |
dc.identifier.issn | 0003-9942 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/111163 | - |
dc.description.abstract | BACKGROUND: The significance of occlusive lesions of the parent artery in patients with lacunar syndrome (LS) and small deep infarcts (SDIs) on diffusion-weighted imaging remains unclear. OBJECTIVE: To compare the recurrence of stroke in patients with LS and SDIs between those with vs without a parent arterial lesion. DESIGN: Analysis of data from a prospective acute stroke registry. SETTING: University hospital. PATIENTS: Using clinical syndrome, diffusion-weighted imaging, and vascular studies, we divided 173 patients into 3 groups: (1) parent arterial disease occluding deep perforators (PAD), LS with SDIs, and a parent arterial lesion (n = 32); (2) small artery disease (SAD) (n = 70); and (3) large artery disease (LAD) (n = 71). MAIN OUTCOME MEASURES: Recurrent strokes and the prognosis were registered for 1 year, and the outcome of the PAD group was compared with that of the SAD and LAD groups. RESULTS: During follow-up, there were 9 deaths (6 vascular) and 18 recurrent strokes. The recurrence rate in the PAD group (16%) was significantly higher than that in the SAD group (1%) (P =.01) but similar to that in the LAD group (17%) (P =.87). The presence of the parent arterial lesion was the only independent predictor of stroke recurrence in patients with LS and SDIs (odds ratio, 13.8; 95% confidence interval, 1.5-123.9; P =.02). CONCLUSIONS: Although LS on examination, SDIs on diffusion-weighted imaging, and a stable hospital course suggest lacunar stroke of benign course, our results indicate that the PAD group represents an intracranial type of LAD. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 514~519 | - |
dc.relation.isPartOf | ARCHIVES OF NEUROLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Arterial Occlusive Diseases/complications* | - |
dc.subject.MESH | Arterial Occlusive Diseases/diagnosis | - |
dc.subject.MESH | Arterial Occlusive Diseases/mortality | - |
dc.subject.MESH | Brain Infarction/diagnosis | - |
dc.subject.MESH | Brain Infarction/etiology* | - |
dc.subject.MESH | Brain Infarction/mortality | - |
dc.subject.MESH | Cerebral Arterial Diseases/complications* | - |
dc.subject.MESH | Cerebral Arterial Diseases/diagnosis | - |
dc.subject.MESH | Cerebral Arterial Diseases/mortality | - |
dc.subject.MESH | Diagnosis, Differential | - |
dc.subject.MESH | Diffusion Magnetic Resonance Imaging* | - |
dc.subject.MESH | Dominance, Cerebral/physiology | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Recurrence | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Sensitivity and Specificity | - |
dc.subject.MESH | Survival Rate | - |
dc.title | The course of patients with lacunar infarcts and a parent arterial lesion: similarities to large artery vs small artery disease | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Neurology (신경과학) | - |
dc.contributor.googleauthor | Oh Young Bang | - |
dc.contributor.googleauthor | Sung Yeol Joo | - |
dc.contributor.googleauthor | Kyoon Huh | - |
dc.contributor.googleauthor | In Soo Joo | - |
dc.contributor.googleauthor | Jae Hyuk Lee | - |
dc.contributor.googleauthor | Uk Shik Joo | - |
dc.contributor.googleauthor | Phil Hyu Lee | - |
dc.identifier.doi | 10.1001/archneur.61.4.514 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03084 | - |
dc.contributor.localId | A03270 | - |
dc.relation.journalcode | J00223 | - |
dc.identifier.eissn | 1538-3687 | - |
dc.identifier.pmid | 15096399 | - |
dc.identifier.url | http://archneur.jamanetwork.com/article.aspx?articleid=785673 | - |
dc.contributor.alternativeName | Lee, Jae Hyuk | - |
dc.contributor.alternativeName | Lee, Phil Hyu | - |
dc.contributor.affiliatedAuthor | Lee, Jae Hyuk | - |
dc.contributor.affiliatedAuthor | Lee, Phil Hyu | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 61 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 514 | - |
dc.citation.endPage | 519 | - |
dc.identifier.bibliographicCitation | ARCHIVES OF NEUROLOGY , Vol.61(4) : 514-519, 2004 | - |
dc.identifier.rimsid | 36177 | - |
dc.type.rims | ART | - |
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