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해양심층수가 피부장벽에 미치는 영향
DC Field | Value | Language |
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dc.contributor.author | 김현정 | - |
dc.contributor.author | 이승헌 | - |
dc.date.accessioned | 2015-06-10T13:06:18Z | - |
dc.date.available | 2015-06-10T13:06:18Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 1225-8180 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/111016 | - |
dc.description.abstract | Ocean bathing has been considered as ‘healthy’ for skin. Balneotherapy using spa water or Dead Sea water has been alleged to be effective for the management of inflammatory skin diseases, such an atopic dermatitis and psoriasis. Our aim was to investigate the effects of deep sea water and additional salts on skin barrier function of hairless mouse and experimentaly induced irritant contact dermatitis in human. Repeated tape stripping was performed on flank skin of hairless mouse to disrupt epidermal permeability barrier. After barrier perturbation, the barrier-disrupted skin site was immersed in deep sea water or other salt solutions. Barrier recovery rate was evaluated by measuring trasepidermal water loss at 3 and 6 hours after barrier disruption. Sodium dodecyl sulphate solution was used for inducing irritant contact dermatitis in healthy volunteers and epidermal permeability function and skin capacitance change was observed. The barrier recovery was accelerated in deep sea water-immersed skin, compare to distilled water-immersed skin. In experimentally induced irritant contact dermatitis, deep sea water immersion prevented increase of TEWL and decrease of skin capacitance, as compared with distilled water immersion. Deep sea water immersion has beneficial effects on epidermal permeability barrier function. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 59~65 | - |
dc.relation.isPartOf | Korean Journal of InvestigativeDermatology (대한피부연구학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 해양심층수가 피부장벽에 미치는 영향 | - |
dc.title.alternative | Evaluation of Deep Sea Water on Skin Barrier Function | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Dermatology (피부과학) | - |
dc.contributor.googleauthor | 조한경 | - |
dc.contributor.googleauthor | 김현정 | - |
dc.contributor.googleauthor | 최선영 | - |
dc.contributor.googleauthor | 이상은 | - |
dc.contributor.googleauthor | 정세규 | - |
dc.contributor.googleauthor | 최응호 | - |
dc.contributor.googleauthor | 안성구 | - |
dc.contributor.googleauthor | 이승헌 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02931 | - |
dc.contributor.localId | A01128 | - |
dc.relation.journalcode | J02042 | - |
dc.subject.keyword | Capacitance | - |
dc.subject.keyword | Deep sea water | - |
dc.subject.keyword | Skin barrier | - |
dc.subject.keyword | Transepidermal water loss | - |
dc.contributor.alternativeName | Kim, Hyun Jung | - |
dc.contributor.alternativeName | Lee, Seung Hun | - |
dc.contributor.affiliatedAuthor | Lee, Seung Hun | - |
dc.contributor.affiliatedAuthor | Kim, Hyun Jung | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 13 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 59 | - |
dc.citation.endPage | 65 | - |
dc.identifier.bibliographicCitation | Korean Journal of InvestigativeDermatology (대한피부연구학회지), Vol.13(2) : 59-65, 2006 | - |
dc.identifier.rimsid | 51920 | - |
dc.type.rims | ART | - |
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