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Botulinum Toxin Type A Injection for Management of Upper Limb Spasticity in Children with Cerebral Palsy: a Literature Review

DC Field Value Language
dc.contributor.author나동욱-
dc.contributor.author박은숙-
dc.date.accessioned2015-06-10T13:05:03Z-
dc.date.available2015-06-10T13:05:03Z-
dc.date.issued2006-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/110977-
dc.description.abstractThe aim of this article was to present a review of the research literature on the outcome of botulinum toxin type A (BTX-A) injection for management of upper limb spasticity in children with cerebral palsy (CP). We searched the electronic databases of MEDLINE, CINAHL and PUBMED for all published studies with full-length English text available. For each study, the quality of the methods and the strength of evidence were assessed by 2 independent reviewers based on the American Academy for Cerebral Palsy and Developmental Medicine (AACPDM) guidelines. Four studies of level I, 8 studies of level IV and 4 studies of level V were identified. Due to the limited number of studies with high quality evidence and inconsistent results among studies, we were unable to support or refute the usefulness of BTX-A injection for management of upper limb spasticity in children with CP. Moreover, we identified several variables that may affect the outcome of injection, such as timing of age, dosage, dilution volumes, localization techniques of target muscles and participant characteristics. In summary, we have presented a review the literature and a discussion of the considerable uncertainty and variation associated with the clinical use of BTX-A injection for management of upper limb spasticity in children with CP.-
dc.description.statementOfResponsibilityopen-
dc.format.extent589~603-
dc.relation.isPartOfYONSEI MEDICAL JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdolescent-
dc.subject.MESHAdult-
dc.subject.MESHAge Factors-
dc.subject.MESHBotulinum Toxins, Type A/administration & dosage-
dc.subject.MESHBotulinum Toxins, Type A/therapeutic use*-
dc.subject.MESHCerebral Palsy/drug therapy*-
dc.subject.MESHChild-
dc.subject.MESHChild, Preschool-
dc.subject.MESHHumans-
dc.subject.MESHInfant-
dc.subject.MESHInjections-
dc.subject.MESHMuscle Spasticity/drug therapy-
dc.subject.MESHNeuromuscular Agents/administration & dosage-
dc.subject.MESHNeuromuscular Agents/therapeutic use*-
dc.subject.MESHRange of Motion, Articular/drug effects-
dc.subject.MESHUpper Extremity-
dc.titleBotulinum Toxin Type A Injection for Management of Upper Limb Spasticity in Children with Cerebral Palsy: a Literature Review-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Rehabilitation Medicine (재활의학)-
dc.contributor.googleauthorEun Sook Park-
dc.contributor.googleauthorDong-wook Rha-
dc.identifier.doi10.3349/ymj.2006.47.5.589-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01230-
dc.contributor.localIdA01611-
dc.relation.journalcodeJ02813-
dc.identifier.eissn1976-2437-
dc.identifier.pmid17066503-
dc.subject.keywordCerebral palsy-
dc.subject.keywordbotulinum toxin type A-
dc.subject.keywordspasticity-
dc.subject.keywordupper limb-
dc.contributor.alternativeNameRha, Dong Wook-
dc.contributor.alternativeNamePark, Eun Sook-
dc.contributor.affiliatedAuthorRha, Dong Wook-
dc.contributor.affiliatedAuthorPark, Eun Sook-
dc.rights.accessRightsfree-
dc.citation.volume47-
dc.citation.number5-
dc.citation.startPage589-
dc.citation.endPage603-
dc.identifier.bibliographicCitationYONSEI MEDICAL JOURNAL, Vol.47(5) : 589-603, 2006-
dc.identifier.rimsid51894-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학교실) > 1. Journal Papers

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