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Cited 12 times in

The Effect of Milrinone on the Right Ventriclular Function in Patients with Reduced Right Ventricular Function Undergoing Off-pump Coronary Artery Bypass Graft Surgery

DC Field Value Language
dc.contributor.author심연희-
dc.contributor.author오영준-
dc.contributor.author이기종-
dc.contributor.author이종화-
dc.contributor.author홍용우-
dc.contributor.author곽영란-
dc.date.accessioned2015-06-10T13:04:33Z-
dc.date.available2015-06-10T13:04:33Z-
dc.date.issued2006-
dc.identifier.issn1011-8934-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/110961-
dc.description.abstractThis investigation evaluated the effect of continuous milrinone infusion on right ventriclular (RV) function during off-pump coronary artery bypass graft (OPCAB) surgery in patients with reduced RV function. Fifty patients scheduled for OPCAB, with thermodilution RV ejection fraction (RVEF) <35% after anesthesia induction, were randomly allocated to either milrinone (0.5 µg/kg/min) or control (saline) group. Hemodynamic variables and RV volumetric data measured by thermodilution method were collected as follows: after anesthesia induction (T1); 10 min after heart displacement for obtuse marginal artery anastomosis (T2); after pericardial closure (T3). Cardiac index and heart rate increased and systemic vascular resistance significantly decreased in milrinone group at T2. Initially lower RVEF of milrinone group was eventually comparable to control group after milrinone infusion. RVEF did not significantly change at T2 and T3 in both groups. RV end-diastolic volume in milrinone group consistently decreased from the baseline at T2 and T3. Continuous infusion of milrinone without a bolus demonstrated potentially beneficial effect on cardiac output and RV afterload in patients with reduced RV function during OPCAB. However, aggressive augmentation of intravascular volume seems to be necessary to maximize the effect of the milrinone in these patients.-
dc.description.statementOfResponsibilityopen-
dc.format.extent854~858-
dc.relation.isPartOfJOURNAL OF KOREAN MEDICAL SCIENCE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged-
dc.subject.MESHBlood Pressure/drug effects-
dc.subject.MESHCoronary Artery Bypass, Off-Pump*-
dc.subject.MESHEchocardiography, Transesophageal-
dc.subject.MESHFemale-
dc.subject.MESHHeart Rate/drug effects-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMilrinone/pharmacology*-
dc.subject.MESHPhosphodiesterase Inhibitors/pharmacology*-
dc.subject.MESHVentricular Function, Right/drug effects*-
dc.titleThe Effect of Milrinone on the Right Ventriclular Function in Patients with Reduced Right Ventricular Function Undergoing Off-pump Coronary Artery Bypass Graft Surgery-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Thoracic & Cardiovascular Surgery (흉부외과학)-
dc.contributor.googleauthorJong Hwa Lee-
dc.contributor.googleauthorYoung Jun Oh-
dc.contributor.googleauthorYon Hee Shim-
dc.contributor.googleauthorYong Woo Hong-
dc.contributor.googleauthorGijong Yi-
dc.contributor.googleauthorYoung Lan Kwak-
dc.identifier.doi10.3346/jkms.2006.21.5.854-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02196-
dc.contributor.localIdA02389-
dc.contributor.localIdA02697-
dc.contributor.localIdA03154-
dc.contributor.localIdA04420-
dc.contributor.localIdA00172-
dc.relation.journalcodeJ01517-
dc.identifier.eissn1598-6357-
dc.identifier.pmid17043419-
dc.subject.keywordMilrinone-
dc.subject.keywordVentricular Function-
dc.subject.keywordRight-
dc.subject.keywordThermodilution-
dc.subject.keywordCoronary Artery Bypass-
dc.subject.keywordOff-pump-
dc.contributor.alternativeNameShim, Yon Hee-
dc.contributor.alternativeNameOh, Young Jun-
dc.contributor.alternativeNameYi, Gi Jong-
dc.contributor.alternativeNameLee, Jong Wha-
dc.contributor.alternativeNameHong, Yong Woo-
dc.contributor.alternativeNameKwak, Young Lan-
dc.contributor.affiliatedAuthorShim, Yon Hee-
dc.contributor.affiliatedAuthorOh, Young Jun-
dc.contributor.affiliatedAuthorYi, Gi Jong-
dc.contributor.affiliatedAuthorLee, Jong Wha-
dc.contributor.affiliatedAuthorHong, Yong Woo-
dc.contributor.affiliatedAuthorKwak, Young Lan-
dc.rights.accessRightsfree-
dc.citation.volume21-
dc.citation.number5-
dc.citation.startPage854-
dc.citation.endPage858-
dc.identifier.bibliographicCitationJOURNAL OF KOREAN MEDICAL SCIENCE, Vol.21(5) : 854-858, 2006-
dc.identifier.rimsid55930-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers

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