Cited 0 times in

비당뇨병성 말기신부전증 환자에서 양측성 기저핵 병변과 소뇌 병변을 동반한 요독성 뇌병증

DC Field Value Language
dc.contributor.author박우일-
dc.contributor.author박형천-
dc.contributor.author배기선-
dc.contributor.author심성록-
dc.contributor.author이경열-
dc.contributor.author임재윤-
dc.contributor.author장재훈-
dc.contributor.author하성규-
dc.contributor.author김기중-
dc.date.accessioned2015-06-10T13:00:33Z-
dc.date.available2015-06-10T13:00:33Z-
dc.date.issued2006-
dc.identifier.issn1225-0015-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/110842-
dc.description.abstractInvolvement of central nervous system is a well-known compication in uremic patients. However, development of acute extrapyramidal symptoms with bilateral basal ganglia involvement (acute basal ganglia syndrome), especially in non-diabetic hemodialysis patient is very rare. We report a case of acute basal ganglia syndrome in a non-diabetic hemodialysis patient. A 45-year-old man with autosomal dominant polycystic kidney disease (ADPKD) on chronic hemodialysis treatment for the last 4 years was admitted due to generalized myalgia. On admission, the patient was found to have rhabdomyolysis and intractable metabolic acidosis. Nine days after admission, he suddenly developed dysarthria, lateralizing ataxia, and bradykinesia. Brain MRI demonstrated low and high signals in bilateral basal ganglia and cerebellar vermis in T1-weighted and T2-weighted images, respectively. Intensified hemodialysis treatment combined with general supportive therapy resolved the severe metabolic acidosis and the neurologic manifestations gradually improved. Follow up brain CT scan taken 3 months later showed decreased size of initial low attenuation lesions in bilateral basal ganglia and cerebellar vermis. Although no definite pathophysiology is yet established, severe metabolic disorder is believed to play an important role in development of acute basal ganglia syndrome. Correction of metabolic acidosis and hypoglycemia in our patient lead to improvement in neurologic manifestations and organic brain lesions. Our case suggests that severe metabolic acidosis and hypoglycemia in uremic patient may act as risk factors for acute basal ganglia syndrome even in non-diabetic patient.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.relation.isPartOfKorean Journal of Nephrology (대한신장학회지)-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.title비당뇨병성 말기신부전증 환자에서 양측성 기저핵 병변과 소뇌 병변을 동반한 요독성 뇌병증-
dc.title.alternativeUremic Encephalopathy Associated with Bilateral Basal Ganglia and Cerebellar Lesion in a Non-diabetic Hemodialysis Patient-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthor심성록-
dc.contributor.googleauthor이상훈-
dc.contributor.googleauthor장재훈-
dc.contributor.googleauthor임재윤-
dc.contributor.googleauthor최유경-
dc.contributor.googleauthor배기선-
dc.contributor.googleauthor박우일-
dc.contributor.googleauthor김기중-
dc.contributor.googleauthor이경열-
dc.contributor.googleauthor박형천-
dc.contributor.googleauthor하성규-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01586-
dc.contributor.localIdA01759-
dc.contributor.localIdA01791-
dc.contributor.localIdA02194-
dc.contributor.localIdA02648-
dc.contributor.localIdA03398-
dc.contributor.localIdA03466-
dc.contributor.localIdA04252-
dc.contributor.localIdA00341-
dc.contributor.localIdA02836-
dc.relation.journalcodeJ02066-
dc.subject.keywordBilateral basal ganglia-
dc.subject.keywordCerebellar vermis-
dc.subject.keywordMetabolic acidosis-
dc.subject.keywordNon-dia betic ESRD-
dc.subject.keywordUremic encephalopathy-
dc.contributor.alternativeNamePark, Woo Il-
dc.contributor.alternativeNamePark, Hyeong Cheon-
dc.contributor.alternativeNameBae, Ki Sun-
dc.contributor.alternativeNameSim, Soung Rok-
dc.contributor.alternativeNameLee, Kyung Yul-
dc.contributor.alternativeNameLee, Sang Hoon-
dc.contributor.alternativeNameLim, Jae Yun-
dc.contributor.alternativeNameJahng, Jae Hoon-
dc.contributor.alternativeNameHa, Sung Kyu-
dc.contributor.alternativeNameKim, Ki Joong-
dc.contributor.affiliatedAuthorPark, Woo Il-
dc.contributor.affiliatedAuthorPark, Hyeong Cheon-
dc.contributor.affiliatedAuthorBae, Ki Sun-
dc.contributor.affiliatedAuthorSim, Soung Rok-
dc.contributor.affiliatedAuthorLee, Kyung Yul-
dc.contributor.affiliatedAuthorLim, Jae Yun-
dc.contributor.affiliatedAuthorJahng, Jae Hoon-
dc.contributor.affiliatedAuthorHa, Sung Kyu-
dc.contributor.affiliatedAuthorKim, Ki Joong-
dc.contributor.affiliatedAuthorLee, Sang Hoon-
dc.rights.accessRightsfree-
dc.citation.volume25-
dc.citation.number6-
dc.citation.startPage1061-
dc.citation.endPage1066-
dc.identifier.bibliographicCitationKorean Journal of Nephrology, Vol.25(6) : 1061-1066, 2006-
dc.identifier.rimsid54478-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.