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Effects of corneal neovascularization on the manifestations of Avellino corneal dystrophy (granular corneal dystrophy type II)

Authors
 Jae Hwan Lee  ;  So-Hyang Chung  ;  R. Doyle Stulting  ;  Woon Cho Kim  ;  Hyung Keun Lee  ;  Eung Kweon Kim 
Citation
 CORNEA, Vol.25(8) : 914-918, 2006 
Journal Title
 CORNEA 
ISSN
 0277-3740 
Issue Date
2006
MeSH
Adult ; Aged, 80 and over ; Cornea/pathology ; Corneal Dystrophies, Hereditary/etiology* ; Corneal Dystrophies, Hereditary/physiopathology ; Corneal Neovascularization/complications* ; Corneal Neovascularization/physiopathology ; Corneal Opacity/prevention & control ; Female ; Humans ; Male ; Middle Aged ; Pterygium/complications
Keywords
Avellino corneal dystrophy ; pterygium ; corneal neo-vascularization
Abstract
PURPOSE: To evaluate the corneal deposits of Avellino corneal dystrophy (ACD) in patients with corneal neovascularization from pterygium or phthisis bulbi as a way of understanding the pathogenesis of ACD. METHODS: Five patients with ACD with pterygium, 10 patients with ACD (age >50 years) without pterygium, 1 patient with ACD with phthisis bulbi with corneal neovascularization, and 1 patient with ACD with phthisis bulbi without corneal neovascularization were examined. The corneal deposits of all patients were assessed by slit-lamp examination and reviewed with biomicroscopic photographs. The distance between the limbus and the nearest corneal opacities was measured. RESULTS: In eyes with vascularized nasal pterygia, there was a granule-free zone adjacent to the advancing edge of the pterygium so that the distance between the nasal limbus and the most nasally located granule exceeds that of the distance between the limbus and the closest granule elsewhere on the cornea. In patients with ACD with phthisis bulbi, no granular deposits were observed in the cornea with neovascularization, but there were deposits in the cornea without neovascularization. CONCLUSION: Corneal neovascularization prevents the deposition of corneal opacities in patients with ACD.
Full Text
http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00003226-200609000-00010&LSLINK=80&D=ovft
DOI
10.1097/01.ico.0000224645.89342.55
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Eung Kweon(김응권) ORCID logo https://orcid.org/0000-0002-1453-8042
Lee, Hyung Keun(이형근) ORCID logo https://orcid.org/0000-0002-1123-2136
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/110495
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