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Inhibitory effect of capsaicin on interleukin-8 production by Helicobacter pylori-infected MKN-45 cells

DC Field Value Language
dc.contributor.author김태일-
dc.contributor.author노성훈-
dc.contributor.author이용찬-
dc.date.accessioned2015-06-10T12:46:52Z-
dc.date.available2015-06-10T12:46:52Z-
dc.date.issued2006-
dc.identifier.issn1017-7825-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/110432-
dc.description.abstractThe fructus of Gardenia jasminoides Ellis (GF) has been widely used as a natural colorant in Asian countries, and also as a Chinese traditional medicine for its homeostatic, antiphlogistic, analgesic, and antipyretic effects. In the present study, its main component, crocin, was fermented with lactic acid bacteria (LAB) and their antihyperlipidemic activity was measured. The GF extract, fermented GF (F-GF), crocin, and fermented crocin (F-crocin) significantly inhibited the increase of serum triglyceride (TG) level in corn oil feeding-induced triglyceridemic mice, as well as that of serum TG and total and LDL cholesterol levels in Triton WR-1339-induced hyperlipidemic mice. These agents also showed hypolipidemic activity in hyperlipidemic mice induced by high fat diet for 5 weeks. F-GF and F-crocin exhibited more potent hyperlipidemic effects than GF and crocin. The results suggest that the hypolipidemic effect of GF and crocin can be synergistically activated by LAB, and that F-GF and F-crocin may improve hyperlipidemia in clinic, compared with GF and crocin.-
dc.description.statementOfResponsibilityopen-
dc.format.extent1078~1083-
dc.relation.isPartOfJOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleInhibitory effect of capsaicin on interleukin-8 production by Helicobacter pylori-infected MKN-45 cells-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorLee, Kwang Hyoung-
dc.contributor.googleauthorYong Chan Lee-
dc.contributor.googleauthorTae Il Kim-
dc.contributor.googleauthorSung Hoon Noh-
dc.contributor.googleauthorJi-Yeon Kim-
dc.contributor.googleauthorHyun-Dong Paik-
dc.contributor.googleauthorChang Han Kim-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01079-
dc.contributor.localIdA01281-
dc.contributor.localIdA02988-
dc.relation.journalcodeJ01594-
dc.identifier.eissn1738-8872-
dc.subject.keywordHelicobacter pylori-
dc.subject.keywordcapsaicin-
dc.subject.keywordIL-8-
dc.subject.keywordNF-κB-
dc.contributor.alternativeNameKim, Tae Il-
dc.contributor.alternativeNameNoh, Sung Hoon-
dc.contributor.alternativeNameLee, Yong Chan-
dc.contributor.affiliatedAuthorKim, Tae Il-
dc.contributor.affiliatedAuthorNoh, Sung Hoon-
dc.contributor.affiliatedAuthorLee, Yong Chan-
dc.rights.accessRightsfree-
dc.citation.volume16-
dc.citation.number7-
dc.citation.startPage1078-
dc.citation.endPage1083-
dc.identifier.bibliographicCitationJOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, Vol.16(7) : 1078-1083, 2006-
dc.identifier.rimsid38791-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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