확산강조 뇌자기공명영상에서 대뇌 피질 고영상 병변을 보이는 임상적으로 진단된 크로이츠펠트-야콥병 4예

Abstract

A high signal in the cerebral cortex and/or basal ganglia on a diffusion-weighted MRI (DWI) has been described as a good diagnostic marker for sporadic Creutzfeldt-Jakob disease (sCJD). We report four cases of sCJD with atypical clinical presentations and ribbon-like areas of high signals in the cerebral cortex on DWI. DWI patterns of asymmetric cortical high signals in the cerebral cortex may offer the means for diagnosis of sCJD early in the course of the illness even when the clinical presentations are atypical.