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한센병 병력자들의 C형간염: 유전자형 및 위험요인 연구
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이관식 | - |
dc.date.accessioned | 2015-06-10T12:36:56Z | - |
dc.date.available | 2015-06-10T12:36:56Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 1226-329X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/110131 | - |
dc.description.abstract | Background : On previous reports, the incidence of hepatiti Background : s C in Korean leprous patients is too high (55.6 69%). We investigated the percentage of the lepro ~ us patients with hepatitis C, genotypes, and risk factors in National Sorokdo Hospital. Methods : Out of total 714 leprous patients in National Sorok Methods : do Hospital, 147 selected risky patients (with abnormal AST/ALT, platelet 150,000/mm ≤ 3, known hepatitis C) were tested for hepatitis C antibody (Radioimmunoassay) and finally 45 HCV antibody positive-patients were tested for HCV RT-PCR and genotypes. Results : The percentage of patients with hepatitis C was 30. Results : 61% (45 out of 147 selected risky groups). 35 male and 10 female patients (mean age: 71±9.6) were included. Classifying according to the type of leprosy, 29 (5.57% out of 503) were patients with lepromatous leprosy and 16 (11.94% out of 134) were those with tuberculoid leprosy. Genotypic result for 41 patients was 1b in 16 (39.02%), 2a in 20 (48.78%), other type in 3 (7.32%) and mixed in 2 (4.88%). Only 2 of the patients (4.40%) had experienced blood transfusion before 1990, 20 (44.40%) had taken an operation or tattooing, 3 (6.67%) were given intravenous drugs, 2 (4.44%) were family members as married couple, and as much as 20 (44.40%) had no previously known possible risk factors. Conclusions : Major genotype of hepatitis C in leprous patie Conclusions : nts was 2a and it is different from that of other Korean population without leprosy (p-value= 0.0027). The percentage of patients with hepatitis C was not related to the subclass of the leprosy. Further studies for the non-blood transmission of hepatitis C virus in them and its controls are needed. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 11~16 | - |
dc.relation.isPartOf | Korean Journal of Medicine | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 한센병 병력자들의 C형간염: 유전자형 및 위험요인 연구 | - |
dc.title.alternative | Hepatitis C in Leprous patients : Genotype and risk factor study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | 최재필 | - |
dc.contributor.googleauthor | 이관식 | - |
dc.contributor.googleauthor | 이용제 | - |
dc.contributor.googleauthor | 이충현 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02666 | - |
dc.relation.journalcode | J02059 | - |
dc.contributor.alternativeName | Lee, Kwan Sik | - |
dc.contributor.affiliatedAuthor | Lee, Kwan Sik | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 70 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 11 | - |
dc.citation.endPage | 16 | - |
dc.identifier.bibliographicCitation | Korean Journal of Medicine, Vol.70(1) : 11-16, 2006 | - |
dc.identifier.rimsid | 52513 | - |
dc.type.rims | ART | - |
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