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Operative morbidity and mortality after D2 and D4 extended dissection for advanced gastric cancer: a prospective randomized trial conducted by Asian surgeons.
DC Field | Value | Language |
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dc.contributor.author | 노성훈 | - |
dc.date.accessioned | 2015-06-10T12:36:33Z | - |
dc.date.available | 2015-06-10T12:36:33Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 0172-6390 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/110119 | - |
dc.description.abstract | Background/Aims: A randomized study was per formed to evaluate morbidity and mortality after D2 (level 1 and 2 lymphadenectomy) and D4 (D2 plus lymphadenectomy of para-aortic lymph nodes) dis section for advanced gastric cancer. Methodology: Two hundred and fifty-six patients with advanced gastric adenocarcinoma were enrolled (128 to each group). Patients were randomly allocat ed into D2 (N=128) or D4 (N=128) group. The first and second tiers of lymph nodes are removed in D2 dissection. In D4 gastrectomy, the paraaortic lymph nodes were additionally removed. Results: There was no indication of significant dis tribution bias with regard to age, sex, T-grade, and N-grade between the two groups. Operation time of D4 gastrectomy (369±120 min) was significantly longer than that of D2 gastrectomy (273±1103 min), and blood loss of the D4 group (872±683mL) was sig nificantly greater than that of the D2 group (571±527mL).(PcO.OOl). Five (4%) and two (2%) medical complications developed in the D2 and D4 groups, respectively. Surgical complications devel oped in 28 (22%) and 48 patients (38%) after D2 and D4 gastrectomy. The most common complications were anastomotic leakage, pancreatic fistula, and abdominal abscess. Pancreatic fistula developed in 6 (19%) of 32 patients after D4 plus pancreatosplenectomy, but the inci dence of pancreatic fistula after D2 gastrectomy plus pancreatosplenectomy was low (6%, 1/16). Two patients died within 30 days of operation (0.8%, 2/256), and each patient belonged to the D2 and D4 group. Conclusions: Although there is a significantly high er surgical complication rate in D4 dissection, D4 dis section can be done safely as D2 dissection when per formed by well-trained surgeons. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 389~394 | - |
dc.relation.isPartOf | HEPATO-GASTROENTEROLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Abdominal Abscess/epidemiology | - |
dc.subject.MESH | Abdominal Abscess/etiology* | - |
dc.subject.MESH | Abdominal Abscess/mortality | - |
dc.subject.MESH | Adenocarcinoma/mortality | - |
dc.subject.MESH | Adenocarcinoma/pathology | - |
dc.subject.MESH | Adenocarcinoma/surgery* | - |
dc.subject.MESH | Asia | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Gastrectomy/adverse effects* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Incidence | - |
dc.subject.MESH | Lymph Node Excision/adverse effects* | - |
dc.subject.MESH | Lymph Node Excision/methods | - |
dc.subject.MESH | Lymphatic Metastasis | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Morbidity | - |
dc.subject.MESH | Pancreatic Fistula/epidemiology | - |
dc.subject.MESH | Pancreatic Fistula/etiology* | - |
dc.subject.MESH | Pancreatic Fistula/mortality | - |
dc.subject.MESH | Postoperative Complications* | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Stomach Neoplasms/mortality | - |
dc.subject.MESH | Stomach Neoplasms/pathology | - |
dc.subject.MESH | Stomach Neoplasms/surgery* | - |
dc.subject.MESH | Survival Analysis | - |
dc.subject.MESH | Time Factors | - |
dc.title | Operative morbidity and mortality after D2 and D4 extended dissection for advanced gastric cancer: a prospective randomized trial conducted by Asian surgeons. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학) | - |
dc.contributor.googleauthor | Y Yonemura | - |
dc.contributor.googleauthor | CC Wu | - |
dc.contributor.googleauthor | N Fukushima | - |
dc.contributor.googleauthor | Honda | - |
dc.contributor.googleauthor | E Bandou | - |
dc.contributor.googleauthor | T Kawamura | - |
dc.contributor.googleauthor | S Kamata | - |
dc.contributor.googleauthor | H Yamamoto | - |
dc.contributor.googleauthor | BS Kim | - |
dc.contributor.googleauthor | N Matsuki | - |
dc.contributor.googleauthor | T Sawa | - |
dc.contributor.googleauthor | SH Noh | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01281 | - |
dc.relation.journalcode | J00984 | - |
dc.identifier.pmid | 16795979 | - |
dc.contributor.alternativeName | Noh, Sung Hoon | - |
dc.contributor.affiliatedAuthor | Noh, Sung Hoon | - |
dc.rights.accessRights | not available | - |
dc.citation.volume | 53 | - |
dc.citation.number | 69 | - |
dc.citation.startPage | 389 | - |
dc.citation.endPage | 394 | - |
dc.identifier.bibliographicCitation | HEPATO-GASTROENTEROLOGY, Vol.53(69) : 389-394, 2006 | - |
dc.identifier.rimsid | 52502 | - |
dc.type.rims | ART | - |
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