Cited 43 times in
Lack of toll-like receptor 4 and 2 polymorphisms in Korean patients with bacteremia
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김명수 | - |
dc.contributor.author | 김준명 | - |
dc.contributor.author | 송영구 | - |
dc.contributor.author | 최준용 | - |
dc.date.accessioned | 2015-06-10T12:34:40Z | - |
dc.date.available | 2015-06-10T12:34:40Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/110060 | - |
dc.description.abstract | Toll-like receptors (TLRs) are pattern-recognition receptors that are important in innate immune responses to bacterial infection. The purpose of this study is to describe the prevalence of TLRs genetic variations in the bacteremic patients in Korea. A total of 154 patients with bacteremia and 179 healthy volunteers were included. The Asp299Gly and Thr399Ile allele of the TLR4 gene and Arg753Gln and Arg677Trp allele of the TLR2 gene were tested by PCR-RFLP. The DNA sequences were determined to confirm the PCR-RFLP results. Contrary to the expectation, no genetic polymorphisms were detected in both groups of this study, suggesting that it is very rare in Korean. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 979~982 | - |
dc.relation.isPartOf | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Bacteremia/blood | - |
dc.subject.MESH | Bacteremia/epidemiology* | - |
dc.subject.MESH | Bacteremia/genetics* | - |
dc.subject.MESH | Biomarkers/blood | - |
dc.subject.MESH | DNA Mutational Analysis | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Genetic Predisposition to Disease/epidemiology | - |
dc.subject.MESH | Genetic Predisposition to Disease/genetics | - |
dc.subject.MESH | Genetic Testing/methods | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Korea/epidemiology | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Polymorphism, Single Nucleotide/genetics | - |
dc.subject.MESH | Prevalence | - |
dc.subject.MESH | Risk Assessment/methods* | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Toll-Like Receptor 2/blood | - |
dc.subject.MESH | Toll-Like Receptor 2/genetics* | - |
dc.subject.MESH | Toll-Like Receptor 4/blood | - |
dc.subject.MESH | Toll-Like Receptor 4/genetics* | - |
dc.title | Lack of toll-like receptor 4 and 2 polymorphisms in Korean patients with bacteremia | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Hee Jung Yoon | - |
dc.contributor.googleauthor | Jun Yong Choi | - |
dc.contributor.googleauthor | Chang Oh Kim | - |
dc.contributor.googleauthor | Yoon Seon Park | - |
dc.contributor.googleauthor | Myoung Soo Kim | - |
dc.contributor.googleauthor | Young Keun Kim | - |
dc.contributor.googleauthor | So Youn Shin | - |
dc.contributor.googleauthor | June Myung Kim | - |
dc.contributor.googleauthor | Young Goo Song | - |
dc.identifier.doi | 10.3346/jkms.2006.21.6.979 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00953 | - |
dc.contributor.localId | A02037 | - |
dc.contributor.localId | A04191 | - |
dc.contributor.localId | A00424 | - |
dc.relation.journalcode | J01517 | - |
dc.identifier.eissn | 1598-6357 | - |
dc.identifier.pmid | 17179672 | - |
dc.subject.keyword | Toll-like Receptors | - |
dc.subject.keyword | Polymorphism | - |
dc.subject.keyword | Genetic | - |
dc.subject.keyword | Bacteremia | - |
dc.contributor.alternativeName | Kim, Myoung Soo | - |
dc.contributor.alternativeName | Kim, June Myung | - |
dc.contributor.alternativeName | Song, Young Goo | - |
dc.contributor.alternativeName | Choi, Jun Yong | - |
dc.contributor.affiliatedAuthor | Kim, June Myung | - |
dc.contributor.affiliatedAuthor | Song, Young Goo | - |
dc.contributor.affiliatedAuthor | Choi, Jun Yong | - |
dc.contributor.affiliatedAuthor | Kim, Myoung Soo | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 21 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 979 | - |
dc.citation.endPage | 982 | - |
dc.identifier.bibliographicCitation | JOURNAL OF KOREAN MEDICAL SCIENCE, Vol.21(6) : 979-982, 2006 | - |
dc.identifier.rimsid | 56059 | - |
dc.type.rims | ART | - |
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