Cited 36 times in
Anti-Saccharomyces cerevisiae antibody in intestinal Behçet's disease patients: Relation to clinical course
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김원호 | - |
dc.contributor.author | 김태일 | - |
dc.contributor.author | 김현숙 | - |
dc.contributor.author | 이상길 | - |
dc.date.accessioned | 2015-06-10T12:33:07Z | - |
dc.date.available | 2015-06-10T12:33:07Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 0012-3706 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/110012 | - |
dc.description.abstract | PURPOSE: This study was designed to assess anti-Saccharomyces cerevisiae antibody positive rate in Behçet's disease and intestinal Behçet's disease and to evaluate whether anti-Saccharomyces cerevisiae antibody expression is associated with clinical findings at diagnosis and clinical course of intestinal Behçet's disease. METHODS: One hundred six patients with intestinal Behçet's disease, 30 patients with Behçet's disease, and 45 healthy control subjects were included. Anti-Saccharomyces cerevisiae antibody was detected by indirect immunofluorescence assay. According to anti-Saccharomyces cerevisiae antibody expression, the various parameters at diagnosis, cumulative relapse rates, and cumulative probabilities of operation were analyzed. RESULTS: Anti-Saccharomyces cerevisiae antibody positive rate was 44.3 percent in intestinal Behçet's disease, 3.3 percent in Behçet's disease, and 8.8 percent in healthy control subjects. In patients with intestinal Behçet's disease, age, gender, distribution of Behçet's disease subtype, symptoms, laboratory tests, and colonoscopic findings at diagnosis were not different according to anti-Saccharomyces cerevisiae antibody expression. Cumulative probability of a first operation was significantly higher in anti-Saccharomyces cerevisiae antibody (+) intestinal Behçet's disease than in anti-Saccharomyces cerevisiae antibody (-) intestinal Behçet's disease: 44.8 and 17.2 percent at one year, and 53 and 24.3 percent at two years after diagnosis, respectively (P=0.006). The number of patients who underwent two or more operations was higher in anti-Saccharomyces cerevisiae antibody (+) intestinal Behçet's disease than in anti-Saccharomyces cerevisiae antibody (-) intestinal Behçet's disease (21.3 vs. 8.5 percent). The cumulative relapse rates were not different between the two groups. CONCLUSIONS: Anti-Saccharomyces cerevisiae antibody positive rate was 44.3 percent in intestinal Behçet's disease. Clinical findings at diagnosis and cumulative relapse rates of intestinal Behçet's disease were not found to be associated with anti-Saccharomyces cerevisiae antibody expression. However, patients with anti-Saccharomyces cerevisiae antibody (+) intestinal Behçet's disease were more likely to receive surgical treatment. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1849~1859 | - |
dc.relation.isPartOf | DISEASES OF THE COLON & RECTUM | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Anti-Inflammatory Agents, Non-Steroidal/therapeutic use | - |
dc.subject.MESH | Antibodies, Fungal/blood* | - |
dc.subject.MESH | Behcet Syndrome/diagnosis | - |
dc.subject.MESH | Behcet Syndrome/immunology* | - |
dc.subject.MESH | Behcet Syndrome/therapy | - |
dc.subject.MESH | Case-Control Studies | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Fluorescent Antibody Technique, Indirect | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Intestinal Diseases/diagnosis | - |
dc.subject.MESH | Intestinal Diseases/immunology* | - |
dc.subject.MESH | Intestinal Diseases/therapy | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Mesalamine/therapeutic use | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Recurrence | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Saccharomyces cerevisiae/immunology* | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Anti-Saccharomyces cerevisiae antibody in intestinal Behçet's disease patients: Relation to clinical course | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Chang Hwan Choi | - |
dc.contributor.googleauthor | Tae Il Kim | - |
dc.contributor.googleauthor | Byung Chang Kim | - |
dc.contributor.googleauthor | Sung Jae Shin | - |
dc.contributor.googleauthor | Sang Kil Lee | - |
dc.contributor.googleauthor | Won Ho Kim | - |
dc.contributor.googleauthor | Hyon Suk Kim | - |
dc.identifier.doi | 10.1007/s10350-006-0706-z | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00774 | - |
dc.contributor.localId | A01079 | - |
dc.contributor.localId | A02812 | - |
dc.contributor.localId | A01117 | - |
dc.relation.journalcode | J00744 | - |
dc.identifier.eissn | 1530-0358 | - |
dc.identifier.pmid | 17080284 | - |
dc.identifier.url | http://link.springer.com/article/10.1007/s10350-006-0706-z | - |
dc.subject.keyword | Anti-Saccharomyces cerevisiae antibody | - |
dc.subject.keyword | Intestinal Behçet’s disease | - |
dc.subject.keyword | Surgical treatment | - |
dc.contributor.alternativeName | Kim, Won Ho | - |
dc.contributor.alternativeName | Kim, Tae Il | - |
dc.contributor.alternativeName | Kim, Hyon Suk | - |
dc.contributor.alternativeName | Lee, Sang Kil | - |
dc.contributor.affiliatedAuthor | Kim, Won Ho | - |
dc.contributor.affiliatedAuthor | Kim, Tae Il | - |
dc.contributor.affiliatedAuthor | Lee, Sang Kil | - |
dc.contributor.affiliatedAuthor | Kim, Hyon Suk | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 49 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 1849 | - |
dc.citation.endPage | 1859 | - |
dc.identifier.bibliographicCitation | DISEASES OF THE COLON & RECTUM, Vol.49(12) : 1849-1859, 2006 | - |
dc.identifier.rimsid | 56022 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.