Cited 20 times in
Antiallodynic effects of acupuncture in neuropathic rats
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 배선준 | - |
dc.contributor.author | 이배환 | - |
dc.date.accessioned | 2015-06-10T12:32:31Z | - |
dc.date.available | 2015-06-10T12:32:31Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 0513-5796 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/109993 | - |
dc.description.abstract | Peripheral nerve injury often results in abnormal neuropathic pain such as allodynia or hyperalgesia. Acupuncture, a traditional Oriental medicine, has been used to relieve pain and related symptoms. However, the efficiency of acupuncture in relieving neuropathic pain is not clear. The aim of this study was to investigate the anti-allodynic effects of acupuncture through behavioral and electrophysiological examinations. Male Sprague-Dawley rats were subjected to neuropathic surgery consisting of a tight ligation and transection of the left tibial and sural nerves, under pentobarbital anesthesia. The acupuncture experiment consisted of four different groups, one treated at each of three different acupoints (Zusanli (ST36), Yinlingquan (SP9), and a sham-acupoint) and a control group. Behavioral tests for mechanical allodynia and cold allodynia were performed for up to two weeks postoperatively. Extracellular electrophysiological recordings were made from the dorsal roots using platinum wire electrodes. Mechanical and cold allodynia were significantly reduced after acupuncture treatment at the Zusanli and Yinlingquan acupoints, respectively. Electrophysiological neural responses to von Frey and acetone tests were also reduced after acupuncture at the same two acupoints. These results suggest that acupuncture may be beneficial in relieving neuropathic pain. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 359~366 | - |
dc.relation.isPartOf | YONSEI MEDICAL JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Acupuncture Analgesia* | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Electrophysiology | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Neuralgia/physiopathology | - |
dc.subject.MESH | Neuralgia/therapy* | - |
dc.subject.MESH | Rats | - |
dc.subject.MESH | Rats, Sprague-Dawley | - |
dc.subject.MESH | Spinal Nerve Roots/physiology* | - |
dc.title | Antiallodynic effects of acupuncture in neuropathic rats | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Physiology (생리학) | - |
dc.contributor.googleauthor | Myeoung Hoon Cha | - |
dc.contributor.googleauthor | Ji Soo Choi | - |
dc.contributor.googleauthor | Sun Joon Bai | - |
dc.contributor.googleauthor | Insop Shim | - |
dc.contributor.googleauthor | Hye-jung Lee | - |
dc.contributor.googleauthor | Sum Mi Choi | - |
dc.contributor.googleauthor | Bae Hwan Lee | - |
dc.contributor.googleauthor | Sun Mi Choi | - |
dc.identifier.doi | 10.3349/ymj.2006.47.3.359 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01795 | - |
dc.contributor.localId | A02791 | - |
dc.relation.journalcode | J02813 | - |
dc.identifier.eissn | 1976-2437 | - |
dc.identifier.pmid | 16807985 | - |
dc.subject.keyword | Neuropathic pain | - |
dc.subject.keyword | acupuncture | - |
dc.subject.keyword | acupoint | - |
dc.subject.keyword | allodynia | - |
dc.subject.keyword | electrophysiology | - |
dc.contributor.alternativeName | Bai, Sun Joon | - |
dc.contributor.alternativeName | Lee, Bae Hwan | - |
dc.contributor.affiliatedAuthor | Bai, Sun Joon | - |
dc.contributor.affiliatedAuthor | Lee, Bae Hwan | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 47 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 359 | - |
dc.citation.endPage | 366 | - |
dc.identifier.bibliographicCitation | YONSEI MEDICAL JOURNAL, Vol.47(3) : 359-366, 2006 | - |
dc.identifier.rimsid | 55077 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.