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CTX-M-12와 새로운 CTX-M형 Extended-Spectrum β-Lactamase생성 Klebsiella pneumoniae의 출현
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 용동은 | - |
dc.contributor.author | 이경원 | - |
dc.date.accessioned | 2015-06-10T12:29:45Z | - |
dc.date.available | 2015-06-10T12:29:45Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 1598-6535 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/109907 | - |
dc.description.abstract | Background: The aims of this study were to survey the nation-wide susceptibilities of Klebsiella pneumoniae isolates against ceftazidime and cefotaxime and to determine the prevalence of class A extended-spectrum -lactamases (ESBLs). Methods: During the period of February to July 2004, K. pneumoniae isolates intermediate or resistant to ceftazidime and/or cefotaxime were collected from 12 hospitals in Korea. Antimicrobial susceptibilities were determined by the disk diffusion and the agar dilution methods and ESBL-production was by double-disk synergy test. Ceftazidime or cefotaxime-resistance determinants of the ESBLproducers were transfered to Escherichia coli J53 by transconjugation. Searches for class A ESBL genes were performed by PCR amplication. Results: Among 212 clinical K. pneumoniae isolates, 172 (81%) isolates showed positive results in double-disk synergy test; the most prevalent ESBL was SHV-12 (n=104). Genes encoding ESBLs including SHV-2 (n=6), SHV-2a (n=17), CTX-M-3 (n=18), CTX-M-9 (n=6), CTX-M-12 (n=1), CTX-M- 14 (n=27), CTX-M-15 (n=3), and a novel CTX-M-type -lactamases were also detected. Conclusion: It is concluded that diversity of ESBLs in K. pneumoniae isolates are increasing in Korea. CTX-M-12 has never been reported in Asia, and a novel CTX-M-type ESBL has emerged. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 21~26 | - |
dc.relation.isPartOf | KOREAN JOURNAL OF LABORATORY MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | CTX-M-12와 새로운 CTX-M형 Extended-Spectrum β-Lactamase생성 Klebsiella pneumoniae의 출현 | - |
dc.title.alternative | Emergence of CTX-M-12 and A Novel CTX-M Type Extended-Spectrum -Lactamase producing Klebsiella pneumoniae | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학) | - |
dc.contributor.googleauthor | 배일권 | - |
dc.contributor.googleauthor | 정석훈 | - |
dc.contributor.googleauthor | 이경원 | - |
dc.contributor.googleauthor | 용동은 | - |
dc.contributor.googleauthor | 이종욱 | - |
dc.contributor.googleauthor | 홍성근 | - |
dc.contributor.googleauthor | 김의종 | - |
dc.contributor.googleauthor | 박연준 | - |
dc.contributor.googleauthor | 강정옥 | - |
dc.contributor.googleauthor | 어영 | - |
dc.contributor.googleauthor | 신종희 | - |
dc.contributor.googleauthor | 이위교 | - |
dc.contributor.googleauthor | 안지영 | - |
dc.contributor.googleauthor | 이성희 | - |
dc.contributor.googleauthor | 우건조 | - |
dc.contributor.googleauthor | 곽효선 | - |
dc.identifier.doi | 10.3343/kjlm.2006.26.1.21 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02423 | - |
dc.contributor.localId | A02649 | - |
dc.relation.journalcode | J02044 | - |
dc.subject.keyword | Klebsiella pneumoniae | - |
dc.subject.keyword | Class AESBL | - |
dc.contributor.alternativeName | Yong, Dong Eun | - |
dc.contributor.alternativeName | Lee, Kyung Won | - |
dc.contributor.affiliatedAuthor | Yong, Dong Eun | - |
dc.contributor.affiliatedAuthor | Lee, Kyung Won | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 26 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 21 | - |
dc.citation.endPage | 26 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF LABORATORY MEDICINE , Vol.26(1) : 21-26, 2006 | - |
dc.identifier.rimsid | 55007 | - |
dc.type.rims | ART | - |
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