Cited 13 times in
Severe Hypothyroidism Induced by Thyroid Metastasis of Colon Adenocarcinoma: A Case Report and Review of the Literature
DC Field | Value | Language |
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dc.contributor.author | 김원호 | - |
dc.contributor.author | 이유미 | - |
dc.contributor.author | 임승길 | - |
dc.contributor.author | 정현철 | - |
dc.contributor.author | 홍순원 | - |
dc.date.accessioned | 2015-06-10T12:25:32Z | - |
dc.date.available | 2015-06-10T12:25:32Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 0918-8959 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/109778 | - |
dc.description.abstract | An 85-year-old man who had undergone a right hemicolectomy for colon cancer presented with severe hypothyroidism and hoarseness 21 months after the operation. The serum thyrotropin (TSH) was markedly elevated to 118.14 μIU/mL and serum free thyroxine (fT4) level was markedly suppressed to 0.34 ng/dL. Symptoms of hoarseness and neck swelling were already evident 4 months prior at which time tests for normal thyroid function were performed. The patient was referred due to aggravated pain on his diffusely enlarged hard goiter. An enlarged thyroid with some calcification was noticed in the neck ultrasonography with multiple cervical lymphadenopathies. Core biopsy of the thyroid gland showed invasion of poorly differentiated adenocarcinoma cells. Immunohistochemical studies showed positive staining only for carcinoembryonic antigen (CEA). There were multiple lung parenchymal nodules and adrenal masses at the time of evaluation. The patient was started on palliative chemotherapy with thyroid hormone replacement and gradually became euthyroid. From these findings and the clinical observations, thyroid metastasis with hypothyroidism developing acutely from metastatic colon adenocarcinoma was diagnosed. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 339~343 | - |
dc.relation.isPartOf | ENDOCRINE JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adenocarcinoma/pathology | - |
dc.subject.MESH | Adenocarcinoma/secondary* | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Colonic Neoplasms/pathology* | - |
dc.subject.MESH | Goiter/diagnostic imaging | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hypothyroidism/etiology* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Thyroid Function Tests | - |
dc.subject.MESH | Thyroid Neoplasms/complications* | - |
dc.subject.MESH | Thyroid Neoplasms/pathology | - |
dc.subject.MESH | Thyroid Neoplasms/secondary* | - |
dc.subject.MESH | Thyrotropin/blood | - |
dc.subject.MESH | Thyroxine/blood | - |
dc.subject.MESH | Ultrasonography | - |
dc.title | Severe Hypothyroidism Induced by Thyroid Metastasis of Colon Adenocarcinoma: A Case Report and Review of the Literature | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pathology (병리학) | - |
dc.contributor.googleauthor | Jong Chan YOUN | - |
dc.contributor.googleauthor | Yumie RHEE | - |
dc.contributor.googleauthor | Soo Young PARK | - |
dc.contributor.googleauthor | Won Ho KIM | - |
dc.contributor.googleauthor | Soo Jung KIM | - |
dc.contributor.googleauthor | Hyun Cheol CHUNG | - |
dc.contributor.googleauthor | Soon Won HONG | - |
dc.contributor.googleauthor | Sung-Kil LIM | - |
dc.identifier.doi | 10.1507/endocrj.K05-115 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00774 | - |
dc.contributor.localId | A03012 | - |
dc.contributor.localId | A03375 | - |
dc.contributor.localId | A03773 | - |
dc.contributor.localId | A04411 | - |
dc.relation.journalcode | J00769 | - |
dc.identifier.eissn | 1348-4540 | - |
dc.identifier.pmid | 16714841 | - |
dc.subject.keyword | Hypothyroidism | - |
dc.subject.keyword | Metastatic thyroid cancer | - |
dc.subject.keyword | Colon adenocarcinoma | - |
dc.subject.keyword | Immunohistochemical staining | - |
dc.subject.keyword | Diagnosis | - |
dc.contributor.alternativeName | Kim, Won Ho | - |
dc.contributor.alternativeName | Rhee, Yumie | - |
dc.contributor.alternativeName | Lim, Sung Kil | - |
dc.contributor.alternativeName | Chung, Hyun Cheol | - |
dc.contributor.alternativeName | Hong, Soon Won | - |
dc.contributor.affiliatedAuthor | Kim, Won Ho | - |
dc.contributor.affiliatedAuthor | Rhee, Yumie | - |
dc.contributor.affiliatedAuthor | Lim, Sung Kil | - |
dc.contributor.affiliatedAuthor | Chung, Hyun Cheol | - |
dc.contributor.affiliatedAuthor | Hong, Soon Won | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 53 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 339 | - |
dc.citation.endPage | 343 | - |
dc.identifier.bibliographicCitation | ENDOCRINE JOURNAL, Vol.53(3) : 339-343, 2006 | - |
dc.identifier.rimsid | 53414 | - |
dc.type.rims | ART | - |
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