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아편계 진통제 장기복용에 의한 부신피질 및 성선기능저하증 환자 1예

Other Titles
 A Case of Patient with Opioid-Induced Adrenocortical Insufficiency and Hypogonadism 
 김혜진  ;  김철식  ;  박종숙  ;  박진아  ;  강은석  ;  안철우  ;  차봉수  ;  임승길  ;  김경래  ;  이현철 
 Journal of Korea Society of Endocrinology (대한내분비학회지), Vol.21(3) : 257-260, 2006 
Journal Title
 Journal of Korea Society of Endocrinology (대한내분비학회지) 
Issue Date
Adrenocortical insufficiency ; Hypogonadism ; Oxycodon
Opioids are known to decrease plasma cortisol and testosterone level in human and other mammals. Nowadays, opioid use is exponentially increasing, but little is known about its side effects. With the help of progressive human science, we can habit longer life and as result, are becoming more avid for healthy life. In this respect, analgesics play important role in maintaining good and healthy quality of life. For this reason, it is important to fully understand its side effects and handle it with special precaution. We are reporting a 22-year-old male who had been taken opioid analgesic for more than six years to relieve chronic, intractable headache. Then, his hormone test revealed hypogonadotropic hypogonadism combined with hypoadrenocorticotropic hypoadrenalism but showed no definite clinical features except for sexual frigidity. After two years of oxycodon discontinuation, we reevaluated that his hormone test, and all other laboratory tests returned to the normal range.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kang, Eun Seok(강은석) ORCID logo https://orcid.org/0000-0002-0364-4675
Kim, Kyung Rae(김경래)
Ahn, Chul Woo(안철우) ORCID logo https://orcid.org/0000-0003-3733-7486
Lee, Hyun Chul(이현철)
Lim, Sung Kil(임승길)
Cha, Bong Soo(차봉수) ORCID logo https://orcid.org/0000-0003-0542-2854
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