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자극성 섬유종, 구강백반증 및 구강편평세포암종에서 MMP-2 및MMP-9 발현에 대한 면역조직화학적 연구

DC Field Value Language
dc.contributor.author김진-
dc.contributor.author차인호-
dc.date.accessioned2015-06-10T12:23:14Z-
dc.date.available2015-06-10T12:23:14Z-
dc.date.issued2006-
dc.identifier.issn1225-1577-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/109708-
dc.description.abstractMMP-2 and MMP-9, type IV collagenases which degrade basement membrane, have been known to play important roles in invasion and metastasis of tumor cells, In addition, they seem to be involved in cell differentiation, apoptosis, angiogenesis and immunity, etc. We immunohistochemically examined epithelial and stromal expressions of MMP-2 and MMP-9 in irritation fibroma, oral leukoplakia, and oral squamous cell carcinoma (OSCC) and have some results as follows: 1. Irritation fibromas, oral leukoplakias and OSCCs mostly showed increased expression of MMP-2 and MMP-9 in the epithelium and connective tissue compared with normal mucosa. 2. There was a significant difference in the epithelial expression of MMP-2 and MMP-9 between irritation fibroma and oral leukoplakia. 3. There was a significant difference in the epithelial and stromal expression of MMP-2 and MMP-9 between irritation fibroma and OSCC. 4. There was a significant difference in the stromal expression of MMP-9 between oral leukoplakia and OSCC. We concluded that rritation fibroma, oral leukoplakia and OSCC have somewhat different characteristics of MMP-2 and MMP-9 expressions, which perhaps result from different pathogenesis.-
dc.description.statementOfResponsibilityopen-
dc.format.extent352~359-
dc.languageKorean-
dc.publisher대한구강악안면병리학회-
dc.relation.isPartOfKorean Journal of Oral and Maxillofacial Pathology-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.title자극성 섬유종, 구강백반증 및 구강편평세포암종에서 MMP-2 및MMP-9 발현에 대한 면역조직화학적 연구-
dc.title.alternativeImmunohistochemical study on expression of MMP-2 and MMP-9 inirritation fibroma, oral leukoplakia and oral squamous cell carcinoma-
dc.typeArticle-
dc.contributor.collegeCollege of Dentistry (치과대학)-
dc.contributor.departmentDept. of Oral and Maxillofacial Surgery (구강악안면외과학)-
dc.contributor.googleauthor김문기-
dc.contributor.googleauthor이은하-
dc.contributor.googleauthor김진-
dc.contributor.googleauthor이의웅-
dc.contributor.googleauthor차인호-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA04002-
dc.contributor.localIdA01009-
dc.relation.journalcodeJ02084-
dc.contributor.alternativeNameKim, Jin-
dc.contributor.alternativeNameCha, In Ho-
dc.contributor.affiliatedAuthorCha, In Ho-
dc.contributor.affiliatedAuthorKim, Jin-
dc.rights.accessRightsfree-
dc.citation.volume32-
dc.citation.number4-
dc.citation.startPage352-
dc.citation.endPage359-
dc.identifier.bibliographicCitationKorean Journal of Oral and Maxillofacial Pathology, Vol.32(4) : 352-359, 2006-
dc.identifier.rimsid53370-
dc.type.rimsART-
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Oral Pathology (구강병리학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Oral and Maxillofacial Surgery (구강악안면외과학교실) > 1. Journal Papers

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