Cited 7 times in
Avoidance therapy in reactive dye—induced occupational asthma: long-term follow-up
DC Field | Value | Language |
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dc.contributor.author | 양주영 | - |
dc.contributor.author | 홍천수 | - |
dc.contributor.author | 박중원 | - |
dc.date.accessioned | 2015-06-10T12:21:59Z | - |
dc.date.available | 2015-06-10T12:21:59Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 1081-1206 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/109669 | - |
dc.description.abstract | BACKGROUND: Previous studies reported that early diagnosis and avoidance therapy are the most important factors for prevention of permanent lung impairment; however, few studies have evaluated the long-term prognosis of reactive dye-induced occupational asthma (RD-OA). OBJECTIVE: To evaluate the long-term outcomes of RD-OA. METHODS: Methacholine airway hyperresponsiveness (AHR) and lung functions were evaluated and compared in 26 patients with RD-OA at the time of diagnosis and after complete avoidance of the causative agents. Patients with continued (n = 13) or remitted (n = 6) AHR were further monitored for up to a mean +/- SD of 8.7 +/- 1.8 years. RESULTS: The AHR resolved in 10 (38%) of 26 patients a mean +/- SD of 2.2 +/- 1.3 years after complete avoidance of RDs; however, prebronchodilator forced expiratory volume in 1 second (FEV1) values were not different. Levels of IgE specific to the RD-human serum albumin complex were markedly decreased at first follow-up in 5 RD-atopic patients from whom paired serum samples were compared (P = .02). The AHR disappeared in an additional 5 patients and improved in 4 by the second follow-up. The FEV1 values also improved compared with diagnosis and first follow-up levels. Favorable prognosis was associated with early diagnosis of RD-OA and complete avoidance of the causative agent. No association was found with smoking history, latent periods, the presence of RD specific IgE, baseline provocation concentration that caused a decrease in FEV1 of 20%, or FEV1. CONCLUSIONS: Early diagnosis and avoidance therapy are the most important prognostic factors in RD-OA. The AHR and lung function of patients with RD-OA can sometimes be recovered steadily and slowly through avoidance measures. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 551~556 | - |
dc.relation.isPartOf | ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Asthma/chemically induced* | - |
dc.subject.MESH | Asthma/diagnosis | - |
dc.subject.MESH | Asthma/prevention & control* | - |
dc.subject.MESH | Coloring Agents/adverse effects* | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Immunoglobulin E/blood | - |
dc.subject.MESH | Korea | - |
dc.subject.MESH | Methacholine Chloride | - |
dc.subject.MESH | Occupational Diseases/chemically induced* | - |
dc.subject.MESH | Occupational Diseases/diagnosis | - |
dc.subject.MESH | Occupational Diseases/prevention & control* | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Risk Reduction Behavior* | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Avoidance therapy in reactive dye—induced occupational asthma: long-term follow-up | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Jung-Won Park | - |
dc.contributor.googleauthor | Joo-Young Yang | - |
dc.contributor.googleauthor | Cheol-Woo Kim | - |
dc.contributor.googleauthor | Kyu-Sang Kim | - |
dc.contributor.googleauthor | Chein-Soo Hong | - |
dc.identifier.doi | 10.1016/S1081-1206(10)60949-0 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02320 | - |
dc.contributor.localId | A01681 | - |
dc.contributor.localId | A04448-1 | - |
dc.relation.journalcode | J00153 | - |
dc.identifier.eissn | 1534-4436 | - |
dc.identifier.pmid | 17069113 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S1081120610609490 | - |
dc.contributor.alternativeName | Yang, Joo Young | - |
dc.contributor.alternativeName | Hong, Chein Soo | - |
dc.contributor.alternativeName | Park, Jung Won | - |
dc.contributor.affiliatedAuthor | Yang, Joo Young | - |
dc.contributor.affiliatedAuthor | Park, Jung Won | - |
dc.contributor.affiliatedAuthor | Hong, Chein Soo | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 97 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 551 | - |
dc.citation.endPage | 556 | - |
dc.identifier.bibliographicCitation | ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, Vol.97(4) : 551-556, 2006 | - |
dc.identifier.rimsid | 38908 | - |
dc.type.rims | ART | - |
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