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Avoidance therapy in reactive dye—induced occupational asthma: long-term follow-up

DC Field Value Language
dc.contributor.author양주영-
dc.contributor.author홍천수-
dc.contributor.author박중원-
dc.date.accessioned2015-06-10T12:21:59Z-
dc.date.available2015-06-10T12:21:59Z-
dc.date.issued2006-
dc.identifier.issn1081-1206-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/109669-
dc.description.abstractBACKGROUND: Previous studies reported that early diagnosis and avoidance therapy are the most important factors for prevention of permanent lung impairment; however, few studies have evaluated the long-term prognosis of reactive dye-induced occupational asthma (RD-OA). OBJECTIVE: To evaluate the long-term outcomes of RD-OA. METHODS: Methacholine airway hyperresponsiveness (AHR) and lung functions were evaluated and compared in 26 patients with RD-OA at the time of diagnosis and after complete avoidance of the causative agents. Patients with continued (n = 13) or remitted (n = 6) AHR were further monitored for up to a mean +/- SD of 8.7 +/- 1.8 years. RESULTS: The AHR resolved in 10 (38%) of 26 patients a mean +/- SD of 2.2 +/- 1.3 years after complete avoidance of RDs; however, prebronchodilator forced expiratory volume in 1 second (FEV1) values were not different. Levels of IgE specific to the RD-human serum albumin complex were markedly decreased at first follow-up in 5 RD-atopic patients from whom paired serum samples were compared (P = .02). The AHR disappeared in an additional 5 patients and improved in 4 by the second follow-up. The FEV1 values also improved compared with diagnosis and first follow-up levels. Favorable prognosis was associated with early diagnosis of RD-OA and complete avoidance of the causative agent. No association was found with smoking history, latent periods, the presence of RD specific IgE, baseline provocation concentration that caused a decrease in FEV1 of 20%, or FEV1. CONCLUSIONS: Early diagnosis and avoidance therapy are the most important prognostic factors in RD-OA. The AHR and lung function of patients with RD-OA can sometimes be recovered steadily and slowly through avoidance measures.-
dc.description.statementOfResponsibilityopen-
dc.format.extent551~556-
dc.relation.isPartOfANNALS OF ALLERGY ASTHMA & IMMUNOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAsthma/chemically induced*-
dc.subject.MESHAsthma/diagnosis-
dc.subject.MESHAsthma/prevention & control*-
dc.subject.MESHColoring Agents/adverse effects*-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHImmunoglobulin E/blood-
dc.subject.MESHKorea-
dc.subject.MESHMethacholine Chloride-
dc.subject.MESHOccupational Diseases/chemically induced*-
dc.subject.MESHOccupational Diseases/diagnosis-
dc.subject.MESHOccupational Diseases/prevention & control*-
dc.subject.MESHPrognosis-
dc.subject.MESHRisk Reduction Behavior*-
dc.subject.MESHTreatment Outcome-
dc.titleAvoidance therapy in reactive dye—induced occupational asthma: long-term follow-up-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorJung-Won Park-
dc.contributor.googleauthorJoo-Young Yang-
dc.contributor.googleauthorCheol-Woo Kim-
dc.contributor.googleauthorKyu-Sang Kim-
dc.contributor.googleauthorChein-Soo Hong-
dc.identifier.doi10.1016/S1081-1206(10)60949-0-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02320-
dc.contributor.localIdA01681-
dc.contributor.localIdA04448-1-
dc.relation.journalcodeJ00153-
dc.identifier.eissn1534-4436-
dc.identifier.pmid17069113-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S1081120610609490-
dc.contributor.alternativeNameYang, Joo Young-
dc.contributor.alternativeNameHong, Chein Soo-
dc.contributor.alternativeNamePark, Jung Won-
dc.contributor.affiliatedAuthorYang, Joo Young-
dc.contributor.affiliatedAuthorPark, Jung Won-
dc.contributor.affiliatedAuthorHong, Chein Soo-
dc.rights.accessRightsnot free-
dc.citation.volume97-
dc.citation.number4-
dc.citation.startPage551-
dc.citation.endPage556-
dc.identifier.bibliographicCitationANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, Vol.97(4) : 551-556, 2006-
dc.identifier.rimsid38908-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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