Cited 24 times in
Corticospinal disinhibition in paroxysmal kinesigenic dyskinesia
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 손영호 | - |
dc.contributor.author | 이명식 | - |
dc.date.accessioned | 2015-06-10T12:20:11Z | - |
dc.date.available | 2015-06-10T12:20:11Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 1388-2457 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/109614 | - |
dc.description.abstract | OBJECTIVE: To investigate the underlying mechanism responsible for paroxysmal kinesigenic dyskinesia (PKD). METHODS: We performed a transcranial magnetic stimulation (TMS) study in 12 drug-naïve patients with PKD and 10 healthy volunteers. TMS parameters included resting motor threshold, recruitment curve of motor evoked potential amplitudes, short intracortical inhibition and facilitation, long intracortical inhibition (LICI), and silent period. We also measured compound muscle action potential. RESULTS: LICI, representing GABA-mediated inhibition, was significantly reduced in the patients (P = 0.033), while results for all other TMS parameters tested were comparable between the two groups. CONCLUSIONS AND SIGNIFICANCE: These results suggest that a specific type of corticospinal inhibitory mechanism is impaired in patients with PKD. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 57~60 | - |
dc.relation.isPartOf | CLINICAL NEUROPHYSIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Action Potentials/physiology | - |
dc.subject.MESH | Action Potentials/radiation effects | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Analysis of Variance | - |
dc.subject.MESH | Chorea/physiopathology* | - |
dc.subject.MESH | Electromyography/methods | - |
dc.subject.MESH | Evoked Potentials, Motor/physiology | - |
dc.subject.MESH | Evoked Potentials, Motor/radiation effects | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Neural Inhibition/physiology* | - |
dc.subject.MESH | Neural Inhibition/radiation effects | - |
dc.subject.MESH | Pyramidal Tracts/physiopathology* | - |
dc.subject.MESH | Pyramidal Tracts/radiation effects | - |
dc.subject.MESH | Reaction Time/physiology | - |
dc.subject.MESH | Reaction Time/radiation effects | - |
dc.subject.MESH | Time Factors | - |
dc.subject.MESH | Transcranial Magnetic Stimulation/methods | - |
dc.title | Corticospinal disinhibition in paroxysmal kinesigenic dyskinesia | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Neurology (신경과학) | - |
dc.contributor.googleauthor | S.Y. Kang | - |
dc.contributor.googleauthor | Y.H. Sohn | - |
dc.contributor.googleauthor | H.S. Kim | - |
dc.contributor.googleauthor | C.H. Lyoo | - |
dc.contributor.googleauthor | M.S. Lee | - |
dc.identifier.doi | 10.1016/j.clinph.2005.09.007 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01982 | - |
dc.contributor.localId | A02753 | - |
dc.relation.journalcode | J00592 | - |
dc.identifier.eissn | 1872-8952 | - |
dc.identifier.pmid | 16314144 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S1388245705003779 | - |
dc.subject.keyword | Paroxysmal dyskinesia | - |
dc.subject.keyword | Magnetic stimulation | - |
dc.subject.keyword | GABA | - |
dc.subject.keyword | Motor system | - |
dc.contributor.alternativeName | Sohn, Young Ho | - |
dc.contributor.alternativeName | Lee, Myung Sik | - |
dc.contributor.affiliatedAuthor | Sohn, Young Ho | - |
dc.contributor.affiliatedAuthor | Lee, Myung Sik | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 117 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 57 | - |
dc.citation.endPage | 60 | - |
dc.identifier.bibliographicCitation | CLINICAL NEUROPHYSIOLOGY, Vol.117(1) : 57-60, 2006 | - |
dc.identifier.rimsid | 38869 | - |
dc.type.rims | ART | - |
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