Cited 30 times in
Tissue Engineering of Heart Valves In Vivo Using Bone Marrow-derived Cells
DC Field | Value | Language |
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dc.contributor.author | 장병철 | - |
dc.contributor.author | 홍유선 | - |
dc.date.accessioned | 2015-06-10T12:02:36Z | - |
dc.date.available | 2015-06-10T12:02:36Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 0160-564X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/109087 | - |
dc.description.abstract | In this study, we tissue-engineered heart valves in vivo using autologous bone marrow-derived cells (BMCs). Canine BMCs were differentiated into endothelial cell (EC)-like cells and myofibroblast (MF)-like cells. Decellularized porcine pulmonary valves were seeded with BMCs and implanted to abdominal aorta and pulmonary valve of bone marrow donor dogs. Histological examination of the explants identified the regeneration of valvular structures expressing CD31 and smooth muscle α-actin, indicating the presence of EC-like and MF-like cells in the grafts at 3 and 1 week, respectively, after implantation. Fluorescent microscopic examinations identified the presence of fluorescently labeled cells in the explants, indicating that the implanted BMCs survived and participated in the heart valve reconstitution. This study reports, for the first time, on tissue engineering of heart valve in vivo using BMCs. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 554~557 | - |
dc.relation.isPartOf | ARTIFICIAL ORGANS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Bone Marrow Cells/cytology* | - |
dc.subject.MESH | Cell Differentiation* | - |
dc.subject.MESH | Dogs | - |
dc.subject.MESH | Heart Valves* | - |
dc.subject.MESH | Implants, Experimental | - |
dc.subject.MESH | Tissue Engineering/methods* | - |
dc.title | Tissue Engineering of Heart Valves In Vivo Using Bone Marrow-derived Cells | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Thoracic & Cardiovascular Surgery (흉부외과학) | - |
dc.contributor.googleauthor | Sang-Soo Kim | - |
dc.contributor.googleauthor | Sang-Hyun Lim | - |
dc.contributor.googleauthor | Yoo-Sun Hong | - |
dc.contributor.googleauthor | Seung-Woo Cho | - |
dc.contributor.googleauthor | Ju Hee Ryu | - |
dc.contributor.googleauthor | Byung-Chul Chang | - |
dc.contributor.googleauthor | Cha Yong Choi | - |
dc.contributor.googleauthor | Byung-Soo Kim | - |
dc.identifier.doi | 10.1111/j.1525-1594.2006.00258.x | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03430 | - |
dc.contributor.localId | A04421 | - |
dc.relation.journalcode | J00246 | - |
dc.identifier.eissn | 1525-1594 | - |
dc.identifier.pmid | 16836737 | - |
dc.identifier.url | http://onlinelibrary.wiley.com/doi/10.1111/j.1525-1594.2006.00258.x/abstract | - |
dc.contributor.alternativeName | Chang, Byung Chul | - |
dc.contributor.alternativeName | Hong, You Sun | - |
dc.contributor.affiliatedAuthor | Chang, Byung Chul | - |
dc.contributor.affiliatedAuthor | Hong, You Sun | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 30 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 554 | - |
dc.citation.endPage | 557 | - |
dc.identifier.bibliographicCitation | ARTIFICIAL ORGANS, Vol.30(7) : 554-557, 2006 | - |
dc.identifier.rimsid | 50575 | - |
dc.type.rims | ART | - |
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