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영아 연축 환아에서의 발달 평가 결과

DC FieldValueLanguage
dc.contributor.author김흥동-
dc.contributor.author이영목-
dc.contributor.author이준수-
dc.date.accessioned2015-06-10T11:57:18Z-
dc.date.available2015-06-10T11:57:18Z-
dc.date.issued2006-
dc.identifier.issn1226-6884-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/108923-
dc.description.abstractPurpose : Infantile spasm is the most important epilepsy syndrome that brings catastrophic results in childhood. Persistent spasms and hypsarrhythmia have been known to regress the brain maturation and development. Therefore, it is very important in these patients to find a way to achieve developmental progress as good as possible. The objective of this study was to compare the influence of various etiology on developemental outcome and to determine which therapy has a more favorable development outcome. Methods : We reviewed 95 children diagnosed as infantile spasm between 1991 and 2005 at College of Medicine of Yonsei University and Sang-gye Paik Hospital. We compared possible factors to predict the developmental outcomes in terms of patient characteristics, etiology, seizure duration and seizure outcomes along with various treatment modalities such as antiepileptic drugs, steroid, ketogenic diet, and surgery. Results : Mental retardation occured in 81(85.3%) of the patients with infantile spasms and 38(40.0%) suffered from propound mental retardation. In predicting the developmental outcomes, the most important factor was found to be the etiology. While only 13(56.5%) patients with cryptogenic infantile spasms had severe to profound mental retardation, 53(73.6%) patients with symptomatic etiologies did. Other factors shown to be associated with a good progress included high developmental scores at the onset, a short duration of spasms, an early effective control of spasms, early consideration of non-pharmacologic treatment such as ketogenic diet and surgery when the seizures filed to respond to antiepileptic drugs. Conclusion : This retrospective review suggests that it is possible to improve the developmental outcomes of infantile spasms by making correct etiologic diagnosis and providing early appropriate therapy chosen from variable treatment modalities.-
dc.description.statementOfResponsibilityopen-
dc.format.extent286~294-
dc.relation.isPartOfJournal of the Korean Child Neurology Society (대한소아신경학회지)-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.title영아 연축 환아에서의 발달 평가 결과-
dc.title.alternativeThe Developmental Outcomes of Infantile Spasm-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pediatrics (소아과학)-
dc.contributor.googleauthor서수영-
dc.contributor.googleauthor이영목-
dc.contributor.googleauthor강훈철-
dc.contributor.googleauthor은소희-
dc.contributor.googleauthor이준수-
dc.contributor.googleauthor김흥동-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01208-
dc.contributor.localIdA02955-
dc.contributor.localIdA03177-
dc.relation.journalcodeJ01815-
dc.subject.keywordInfantile spasm-
dc.subject.keywordDevelopment-
dc.subject.keywordAntiepilpetic drug-
dc.subject.keywordSteroid-
dc.subject.keywordKetogenic diet-
dc.subject.keywordEpileptic surgery-
dc.contributor.alternativeNameKim, Heung Dong-
dc.contributor.alternativeNameLee, Young Mock-
dc.contributor.alternativeNameLee, Joon Soo-
dc.contributor.affiliatedAuthorKim, Heung Dong-
dc.contributor.affiliatedAuthorLee, Young Mock-
dc.contributor.affiliatedAuthorLee, Joon Soo-
dc.rights.accessRightsfree-
dc.citation.volume14-
dc.citation.number2-
dc.citation.startPage286-
dc.citation.endPage294-
dc.identifier.bibliographicCitationJournal of the Korean Child Neurology Society (대한소아신경학회지), Vol.14(2) : 286-294, 2006-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers

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