Spleen deposition of Cryptococcus neoformans capsular glucuronoxylomannan in rodents occurs in red pulp macrophages and not marginal zone macrophages expressing the C-type lectin SIGN-R1

Magdia De Jesus; Chae Gyu Park; Ya Su; David L. Goldman; Ralph M. Steinman; Arturo Casadevall

doi:10.1080/13693780701747182

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Spleen deposition of Cryptococcus neoformans capsular glucuronoxylomannan in rodents occurs in red pulp macrophages and not marginal zone macrophages expressing the C-type lectin SIGN-R1

Authors: Magdia De Jesus ; Chae Gyu Park ; Ya Su ; David L. Goldman ; Ralph M. Steinman ; Arturo Casadevall

Citation: MEDICAL MYCOLOGY, Vol.46(2) : 153-162, 2008

Journal Title: MEDICAL MYCOLOGY

ISSN: 1369-3786

Issue Date: 2008

MeSH: Animals ; Cryptococcosis ; Cryptococcus neoformans/chemistry* ; Lectins, C-Type/genetics ; Lectins, C-Type/metabolism* ; Macrophages/classification ; Macrophages/metabolism* ; Polysaccharides/metabolism* ; Rodentia ; Spleen/immunology ; Spleen/metabolism* ; Spleen/microbiology

Keywords: Animals ; Cryptococcosis ; Cryptococcus neoformans/chemistry* ; Lectins, C-Type/genetics ; Lectins, C-Type/metabolism* ; Macrophages/classification ; Macrophages/metabolism* ; Polysaccharides/metabolism* ; Rodentia ; Spleen/immunology ; Spleen/metabolism* ; Spleen/microbiology