Cited 280 times in
Coronary computed tomography angiography as a screening tool for the detection of occult coronary artery disease in asymptomatic individuals
DC Field | Value | Language |
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dc.contributor.author | 장혁재 | - |
dc.date.accessioned | 2015-05-19T17:38:39Z | - |
dc.date.available | 2015-05-19T17:38:39Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 0735-1097 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/108540 | - |
dc.description.abstract | OBJECTIVES: The purpose of this study was to evaluate the prevalence of occult coronary artery disease (CAD) with coronary computed tomography angiography (CTA) to characterize plaque composition and to evaluate the potential of this new technology to impact risk stratification in asymptomatic middle-aged subjects. BACKGROUND: There is a paucity of information regarding the role of CTA for the detection of occult CAD in asymptomatic individuals. METHODS: We consecutively enrolled 1,000 middle-aged asymptomatic subjects (age 50 +/- 9 years, 63% men) who underwent CTA (64-slice multidetector row computed tomography) as part of a general health evaluation. RESULTS: Atherosclerotic plaques were identified in 215 (22%, 2 +/- 1 segments/subject) individuals; 40 individuals (4%) had only noncalcified plaques. Fifty-two (5%) subjects had significant (>or=50%) diameter stenosis and 21 (2%) had severe (>or=75%) stenosis. Thirteen (25%) and 30 (58%) subjects with significant stenosis were classified into National Cholesterol Education Program low-risk and mild coronary calcification (coronary artery calcium scores <100), respectively. Midterm follow-up (17 +/- 2 months) revealed 15 cardiac events only in those with CAD on CTA: 1 unstable angina requiring hospital stay and 14 revascularization procedures. Most (87%) events occurred within 90 days of index CTA. CONCLUSIONS: The prevalence of occult CAD in apparently healthy individuals was not negligible, although their midterm prognosis was good. CTA has a potential to provide a better insight about the occult CAD in this population. However, on the basis of our results and considering present radiation exposure data, we cannot recommend that CTA be used as a screening tool for this population at this point. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 357~365 | - |
dc.relation.isPartOf | JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Calcinosis/diagnostic imaging* | - |
dc.subject.MESH | Coronary Angiography/methods* | - |
dc.subject.MESH | Coronary Artery Disease/diagnostic imaging* | - |
dc.subject.MESH | Coronary Artery Disease/epidemiology | - |
dc.subject.MESH | Coronary Artery Disease/pathology | - |
dc.subject.MESH | Coronary Stenosis/diagnostic imaging | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Image Processing, Computer-Assisted | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Prevalence | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Risk Assessment | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Tomography, X-Ray Computed* | - |
dc.title | Coronary computed tomography angiography as a screening tool for the detection of occult coronary artery disease in asymptomatic individuals | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Eue-Keun Choi | - |
dc.contributor.googleauthor | Sang Il Choi | - |
dc.contributor.googleauthor | Juan J. Rivera | - |
dc.contributor.googleauthor | Khurram Nasir | - |
dc.contributor.googleauthor | Sung-A Chang | - |
dc.contributor.googleauthor | Eun Ju Chun | - |
dc.contributor.googleauthor | Hyung-Kwan Kim | - |
dc.contributor.googleauthor | Dong-Joo Choi | - |
dc.contributor.googleauthor | Roger S. Blumenthal | - |
dc.contributor.googleauthor | Hyuk-Jae Chang | - |
dc.identifier.doi | 10.1016/j.jacc.2008.02.086 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03490 | - |
dc.relation.journalcode | J01770 | - |
dc.identifier.eissn | 1558-3597 | - |
dc.identifier.pmid | 18652943 | - |
dc.subject.keyword | arteriosclerosis | - |
dc.subject.keyword | coronary angiography | - |
dc.subject.keyword | coronary tomography | - |
dc.subject.keyword | mass screening | - |
dc.subject.keyword | X-ray computed | - |
dc.contributor.alternativeName | Chang, Hyuck Jae | - |
dc.contributor.affiliatedAuthor | Chang, Hyuck Jae | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 52 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 357 | - |
dc.citation.endPage | 365 | - |
dc.identifier.bibliographicCitation | JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol.52(5) : 357-365, 2008 | - |
dc.identifier.rimsid | 37069 | - |
dc.type.rims | ART | - |
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