Cited 25 times in
Hemodynamic and prognostic implications of net atrioventricular compliance in patients with mitral stenosis
DC Field | Value | Language |
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dc.contributor.author | 장혁재 | - |
dc.date.accessioned | 2015-05-19T17:38:31Z | - |
dc.date.available | 2015-05-19T17:38:31Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 0894-7317 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/108536 | - |
dc.description.abstract | BACKGROUND: On the basis of the close association of left atrial compliance with pulmonary hypertension in patients with mitral stenosis, we hypothesized that: (1) Doppler-derived net atrioventricular compliance (C(n)) can be used for predicting the occurrence of mitral valve (MV) replacement or percutaneous mitral commissurotomy (PMC); and (2) determinants of exercise capacity are variable depending on C(n). METHODS: We consecutively enrolled 26 patients (22 women; mean age, 47.0 +/- 6.1 years; range, 35-59 years) with pure moderate or severe mitral stenosis, in whom comprehensive echocardiography was performed at rest. C(n) was derived from the equation that has been previously validated (ie, C(n) = 1270 x [MV area by 2-dimensional planimetry/mitral E-wave downslope]. Measurements of stroke volume and systolic pulmonary artery pressure were repeated immediately after symptom-limited treadmill exercise test within 60 seconds. RESULTS: On the basis of earlier reports, C(n) less than 4 mL/mm Hg was selected to define abnormally small C(n). During a mean duration of 24-month follow-up, C(n) of less than 4 mL/mm Hg could reliably predict the occurrence of either MV replacement or PMC, which was confirmed by multivariate logistic regression analysis. In patients with C(n) less than 4 mL/mm Hg, exercise duration was found to be closely correlated primarily with resting systolic pulmonary artery pressure (r = -0.73, P = .03), whereas in patients with C(n) greater than or equal to 4 mL/mm Hg, postexercise stroke volume was the only determinant of exercise capacity (r = 0.49, P = .04). When combining C(n) less than 4 mL/mm Hg with MV area less than 1.0 cm(2) as a cut-off value for predicting MV replacement or PMC, the sensitivity improved from 63.6% to 81.8% (P = .05). CONCLUSIONS: Left atrial compliance estimated by C(n) with Doppler echocardiography allows us to effectively predict the future occurrence of MV replacement or PMC, with a special usefulness in patients with moderate mitral stenosis. In addition, determinants of exercise capacity were variable depending on the degree of C(n). | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 482~486 | - |
dc.relation.isPartOf | JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Atrioventricular Node/diagnostic imaging* | - |
dc.subject.MESH | Echocardiography/methods* | - |
dc.subject.MESH | Exercise Test | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hypertension, Pulmonary/complications* | - |
dc.subject.MESH | Hypertension, Pulmonary/diagnostic imaging* | - |
dc.subject.MESH | Image Interpretation, Computer-Assisted/methods* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Mitral Valve Stenosis/complications* | - |
dc.subject.MESH | Mitral Valve Stenosis/diagnostic imaging* | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Reproducibility of Results | - |
dc.subject.MESH | Risk Assessment/methods* | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Sensitivity and Specificity | - |
dc.title | Hemodynamic and prognostic implications of net atrioventricular compliance in patients with mitral stenosis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Hyung-Kwan Kim | - |
dc.contributor.googleauthor | Yong-Jin Kim | - |
dc.contributor.googleauthor | Seok-Jae Hwang | - |
dc.contributor.googleauthor | Jin-Shik Park | - |
dc.contributor.googleauthor | Hyuk-Jae Chang | - |
dc.contributor.googleauthor | Dae-Won Sohn | - |
dc.contributor.googleauthor | Byung-Hee Oh | - |
dc.contributor.googleauthor | Young-Bae Park | - |
dc.identifier.doi | 10.1016/j.echo.2007.08.024 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03490 | - |
dc.relation.journalcode | J01777 | - |
dc.identifier.eissn | 1097-6795 | - |
dc.identifier.pmid | 17928201 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0894731707005962 | - |
dc.subject.keyword | Adult | - |
dc.subject.keyword | Atrioventricular Node/diagnostic imaging* | - |
dc.subject.keyword | Echocardiography/methods* | - |
dc.subject.keyword | Exercise Test | - |
dc.subject.keyword | Female | - |
dc.subject.keyword | Humans | - |
dc.subject.keyword | Hypertension, Pulmonary/complications* | - |
dc.subject.keyword | Hypertension, Pulmonary/diagnostic imaging* | - |
dc.subject.keyword | Image Interpretation, Computer-Assisted/methods* | - |
dc.subject.keyword | Male | - |
dc.subject.keyword | Middle Aged | - |
dc.subject.keyword | Mitral Valve Stenosis/complications* | - |
dc.subject.keyword | Mitral Valve Stenosis/diagnostic imaging* | - |
dc.subject.keyword | Prognosis | - |
dc.subject.keyword | Reproducibility of Results | - |
dc.subject.keyword | Risk Assessment/methods* | - |
dc.subject.keyword | Risk Factors | - |
dc.subject.keyword | Sensitivity and Specificity | - |
dc.contributor.alternativeName | Chang, Hyuck Jae | - |
dc.contributor.affiliatedAuthor | Chang, Hyuck Jae | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 21 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 482 | - |
dc.citation.endPage | 486 | - |
dc.identifier.bibliographicCitation | JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY, Vol.21(5) : 482-486, 2008 | - |
dc.identifier.rimsid | 37065 | - |
dc.type.rims | ART | - |
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