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Advanced treatment of intractable childgood epilepsy.

DC Field Value Language
dc.contributor.author김흥동-
dc.contributor.author서주희-
dc.contributor.author이준수-
dc.contributor.author최금옥-
dc.date.accessioned2015-05-19T17:38:07Z-
dc.date.available2015-05-19T17:38:07Z-
dc.date.issued2008-
dc.identifier.issn1882-5567-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/108523-
dc.description.abstractTwenty to thirty percent of children with epilepsy continue to have seizures despite anti-epileptic drugs (AEDs) treatment and are defined as medically intractable epilepsy. Intractable epilepsy frequently has developmental impact, causing permanent neurodevelopmental deficits in children. Recently developed neurodiagnostic studies and treatment modalities have substantially altered the management of patients with intractable epilepsy. The newly developed AEDs are frequently used for the treatment of patients unresponsive to conventional AEDs. Nonpharmacologic options for intractable epilepsy include dietary therapy such as ketogenic diet and modified Atkins diet, epilepsy surgery, and neuromodulatory treatments such as vagus nerve stimulation. Ketogenic diet is an effective and safe treatment for epilepsy in children; increasing use has led to modification of protocol for higher efficacy and better tolerability. When epilepsy is intractable to medical treatment, epilepsy surgery including surgical resection of epileptogenic area, or palliative surgery can be considered. Vagal Nerve Stimulation is recommended for patients who are not candidates for resective surgery. These nonpharmcologic treatments could result in resumption of developmental progress in patients with childhood intractable epilepsy.Active application of newly developed medical and surgical treatments could provide better outcome in seizure control and developmental progress in patients with intractable epilepsy-
dc.description.statementOfResponsibilityopen-
dc.format.extent1~10-
dc.relation.isPartOfEpilepsy & Seizure-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleAdvanced treatment of intractable childgood epilepsy.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pediatrics (소아과학)-
dc.contributor.googleauthorJoo Hee Seo-
dc.contributor.googleauthorKum Ok Choi-
dc.contributor.googleauthorJoon Soo Lee-
dc.contributor.googleauthorHeung Dong Kim-
dc.identifier.doi10.3805/eands.1.1-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01208-
dc.contributor.localIdA01910-
dc.contributor.localIdA03177-
dc.contributor.localIdA04044-
dc.relation.journalcodeJ00795-
dc.identifier.pmidIntractable childhood epilepsy ; New antiepileptic drugs ; Ketogenic diet ; Epilepsy Surgery-
dc.subject.keywordIntractable childhood epilepsy-
dc.subject.keywordNew antiepileptic drugs-
dc.subject.keywordKetogenic diet-
dc.subject.keywordEpilepsy Surgery-
dc.contributor.alternativeNameKim, Heung Dong-
dc.contributor.alternativeNameSeo, Joo Hee-
dc.contributor.alternativeNameLee, Joon Soo-
dc.contributor.alternativeNameChoi, Keom Ok-
dc.contributor.affiliatedAuthorKim, Heung Dong-
dc.contributor.affiliatedAuthorSeo, Joo Hee-
dc.contributor.affiliatedAuthorLee, Joon Soo-
dc.contributor.affiliatedAuthorChoi, Keom Ok-
dc.rights.accessRightsfree-
dc.citation.volume1-
dc.citation.number1-
dc.citation.startPage1-
dc.citation.endPage10-
dc.identifier.bibliographicCitationEpilepsy & Seizure, Vol.1(1) : 1-10, 2008-
dc.identifier.rimsid37055-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers

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