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Clinical effects of the levonorgestrel-releasing intrauterine device in patients with adenomyosis

DC Field Value Language
dc.contributor.author김혜연-
dc.contributor.author남안나-
dc.contributor.author박기현-
dc.contributor.author박용원-
dc.contributor.author이병석-
dc.contributor.author조동제-
dc.contributor.author조시현-
dc.contributor.author채두병-
dc.date.accessioned2015-05-19T17:29:03Z-
dc.date.available2015-05-19T17:29:03Z-
dc.date.issued2008-
dc.identifier.issn0002-9378-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/108233-
dc.description.abstractOBJECTIVE: The aim of this study was to evaluate the long-term clinical effects of a levonorgestrel-releasing intrauterine device (LNG-IUD) on adenomyosis. STUDY DESIGN: A LNG-IUD was inserted into 47 patients who were diagnosed with adenomyosis. Uterine volume, uterine artery blood flow, pictorial blood loss assessment chart (PBAC) scores, and the degree of dysmenorrhea were evaluated before and 36 months after insertion of the LNG-IUD. RESULTS: Pain scores and PBAC scores dropped dramatically in 6 months and showed significant decrease after 36 months. A significant decrease in mean uterine volume was noted 12 months (156.85 +/- 49.79 mL to 118.64 +/- 41.36 mL; P < .001) and 24 months (128.84 +/- 48.70 mL; P < .001) after LNG-IUD insertion, but no significant differences were noted at 36 months. The mean pulsatility indices of both uterine arteries increased significantly 12 months after insertion (P = .002 for right; P = .011 for left) and decreased after 24 months without significance. Uterine volume and uterine blood flow were negatively correlated (Pearson's correlation, P < .05). Significant increase of uterine volume, pain scores, and PBAC scores were noted at 36 months compared with 12 months after insertion (P = .034, .021, and .001, respectively). CONCLUSION: For patients with clinical diagnosis of adenomyosis, the LNG-IUD is effective for the reduction of uterine volume with improvement of vascularity and relief of symptoms. However, the efficacy of LNG-IUD on uterine volume may begin to decrease 2 years after insertion.-
dc.description.statementOfResponsibilityopen-
dc.format.extent373.e1-7-
dc.relation.isPartOfAMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHDysmenorrhea/etiology-
dc.subject.MESHEndometriosis/complications-
dc.subject.MESHEndometriosis/drug therapy*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHIntrauterine Devices, Medicated*-
dc.subject.MESHLevonorgestrel/administration & dosage*-
dc.subject.MESHMiddle Aged-
dc.subject.MESHOrgan Size-
dc.subject.MESHPain Measurement-
dc.subject.MESHTreatment Outcome-
dc.subject.MESHUterus/blood supply*-
dc.titleClinical effects of the levonorgestrel-releasing intrauterine device in patients with adenomyosis-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Obstetrics & Gynecology (산부인과학)-
dc.contributor.googleauthorSiHyun Cho-
dc.contributor.googleauthorAnna Nam-
dc.contributor.googleauthorHyeYeon Kim-
dc.contributor.googleauthorDooByung Chay-
dc.contributor.googleauthorKiHyun Park-
dc.contributor.googleauthorDong Je Cho-
dc.contributor.googleauthorYongWon Park-
dc.contributor.googleauthorByungSeok Lee-
dc.identifier.doi10.1016/j.ajog.2007.10.798-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01174-
dc.contributor.localIdA01257-
dc.contributor.localIdA01450-
dc.contributor.localIdA01581-
dc.contributor.localIdA02795-
dc.contributor.localIdA03814-
dc.contributor.localIdA03846-
dc.contributor.localIdA04015-
dc.relation.journalcodeJ00096-
dc.identifier.eissn1097-6868-
dc.identifier.pmid18177833-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0002937807020200-
dc.subject.keywordadenomyosis-
dc.subject.keywordDoppler color flow-
dc.subject.keywordlevonorgestrel intrauterine system-
dc.subject.keyworduterine artery-
dc.subject.keyworduterine volume-
dc.contributor.alternativeNameKim, Hye Yeon-
dc.contributor.alternativeNameNam, An Na-
dc.contributor.alternativeNamePark, Ki Hyun-
dc.contributor.alternativeNamePark, Yong Won-
dc.contributor.alternativeNameLee, Byung Seok-
dc.contributor.alternativeNameCho, Dong Je-
dc.contributor.alternativeNameCho, Si Hyun-
dc.contributor.alternativeNameChay, Doo Byung-
dc.contributor.affiliatedAuthorKim, Hye Yeon-
dc.contributor.affiliatedAuthorNam, An Na-
dc.contributor.affiliatedAuthorPark, Ki Hyun-
dc.contributor.affiliatedAuthorPark, Yong Won-
dc.contributor.affiliatedAuthorLee, Byung Seok-
dc.contributor.affiliatedAuthorCho, Dong Je-
dc.contributor.affiliatedAuthorCho, Si Hyun-
dc.contributor.affiliatedAuthorChay, Doo Byung-
dc.rights.accessRightsnot free-
dc.citation.volume198-
dc.citation.number4-
dc.citation.startPage373-
dc.citation.endPage7-
dc.identifier.bibliographicCitationAMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, Vol.198(4) : 373-7, 2008-
dc.identifier.rimsid35268-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers

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