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Utility of impulse oscillometry in young children with asthma

DC FieldValueLanguage
dc.contributor.author김경원-
dc.contributor.author김규언-
dc.contributor.author김은수-
dc.contributor.author박중원-
dc.contributor.author손명현-
dc.contributor.author송태원-
dc.date.accessioned2015-05-19T17:28:08Z-
dc.date.available2015-05-19T17:28:08Z-
dc.date.issued2008-
dc.identifier.issn0905-6157-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/108205-
dc.description.abstractImpulse Oscillometry (IOS) was developed as a tool to measure lung function, and as it only requires passive cooperation, it has been successfully used in younger children. The aim of this study was to assess the utility of IOS compared to conventional spirometry for lung function measures in asthmatic Korean children aged 3 to 6 yrs. Total serum IgE levels, total eosinophil counts, and specific IgE levels were measured in 77 children with asthma and 55 control subjects. IOS and spirometry were performed in the children before and after bronchodilator administration. Asthmatic children significantly differed from control subjects in baseline resistance at 10 Hz and in their IOS-assessed bronchodilator responses through a Delta resistance at 5 Hz (mean, -27.4% vs. -13.1%; p = 0.002), 10 Hz (mean, -20.4% vs. -11.5%; p = 0.012), 20 Hz (mean, -16.4% vs. -9.4%; p = 0.016), and 35 Hz (mean, -17.2% vs. -10.2%; p = 0.020). Conventional spirometry did not show statistically significant findings. Asthmatic children significantly differed from control subjects in IOS-assessed bronchodilator response through a Delta resistance at 5 Hz, both in atopic children and in non-atopic children. For atopic children, atopic asthmatic children (n = 58) also significantly differed from atopic controls (n = 30) in baseline resistance at 10 Hz, 20 Hz, 35 Hz and impedance and in IOS-assessed bronchodilator responses through a Delta resistance at 10 Hz and 35 Hz. There were some significant correlations between bronchodilator responses of spirometric parameters and IOS parameters. IOS is useful diagnostic tool in early asthma development and might be a helpful objective outcome measure of early interventions.-
dc.description.statementOfResponsibilityopen-
dc.format.extent763~768-
dc.relation.isPartOfPEDIATRIC ALLERGY AND IMMUNOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAlbuterol-
dc.subject.MESHAsthma/diagnosis*-
dc.subject.MESHAsthma/immunology-
dc.subject.MESHAsthma/physiopathology-
dc.subject.MESHBronchodilator Agents-
dc.subject.MESHChild-
dc.subject.MESHChild, Preschool-
dc.subject.MESHEosinophils/immunology-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHImmunoglobulin E/blood-
dc.subject.MESHMale-
dc.subject.MESHOscillometry*-
dc.subject.MESHRespiratory Function Tests*-
dc.subject.MESHSpirometry-
dc.titleUtility of impulse oscillometry in young children with asthma-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pediatrics (소아과학)-
dc.contributor.googleauthorTae Won Song-
dc.contributor.googleauthorKyung Won Kim-
dc.contributor.googleauthorEun Soo Kim-
dc.contributor.googleauthorJung-Won Park-
dc.contributor.googleauthorMyung Hyun Sohn-
dc.contributor.googleauthorKyu-Earn Kim-
dc.identifier.doi10.1111/j.1399-3038.2008.00734.x-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00303-
dc.contributor.localIdA00327-
dc.contributor.localIdA01681-
dc.contributor.localIdA01967-
dc.contributor.localIdA02072-
dc.contributor.localIdA00805-
dc.relation.journalcodeJ02475-
dc.identifier.eissn1399-3038-
dc.identifier.pmid18331417-
dc.identifier.urlhttp://onlinelibrary.wiley.com/doi/10.1111/j.1399-3038.2008.00734.x/abstract-
dc.subject.keywordasthma-
dc.subject.keywordatopy-
dc.subject.keywordchildren-
dc.subject.keywordimpulse oscillometry-
dc.subject.keywordlung function-
dc.subject.keywordspirometry-
dc.contributor.alternativeNameKim, Kyung Won-
dc.contributor.alternativeNameKim, Kyu Earn-
dc.contributor.alternativeNameKim, Eun Soo-
dc.contributor.alternativeNamePark, Jung Won-
dc.contributor.alternativeNameSon, Myung Hyun-
dc.contributor.alternativeNameSong, Tae Won-
dc.contributor.affiliatedAuthorKim, Kyung Won-
dc.contributor.affiliatedAuthorKim, Kyu Earn-
dc.contributor.affiliatedAuthorPark, Jung Won-
dc.contributor.affiliatedAuthorSon, Myung Hyun-
dc.contributor.affiliatedAuthorSong, Tae Won-
dc.contributor.affiliatedAuthorKim, Eun Soo-
dc.rights.accessRightsnot free-
dc.citation.volume19-
dc.citation.number8-
dc.citation.startPage763-
dc.citation.endPage768-
dc.identifier.bibliographicCitationPEDIATRIC ALLERGY AND IMMUNOLOGY, Vol.19(8) : 763-768, 2008-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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