Cited 4 times in
Effect of human papilloma virus expression on clinical course of laryngeal papilloma
DC Field | Value | Language |
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dc.contributor.author | 김광문 | - |
dc.contributor.author | 김세헌 | - |
dc.contributor.author | 김영호 | - |
dc.contributor.author | 조남훈 | - |
dc.contributor.author | 최홍식 | - |
dc.date.accessioned | 2015-05-19T17:27:20Z | - |
dc.date.available | 2015-05-19T17:27:20Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 0001-6489 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/108180 | - |
dc.description.abstract | CONCLUSION: Our observations suggest that human papilloma virus (HPV) 6/11 is the main causative agent of laryngeal papilloma and that detection of active HPV DNA expression may be helpful in identifying patients with aggressive recurrent laryngeal papilloma. OBJECTIVES: HPV is assumed to be the main causative agent of this disease. We investigated the expression of the entire genotype of HPV in cases of laryngeal papilloma and correlated their expression with the clinical course of the disease. SUBJECTS AND METHODS: Seventy cases of laryngeal papilloma were evaluated for the presence of the HPV genome by in situ hybridization (ISH) using wide-spectrum HPV DNA probe. Specific types of HPV infection were determined by DNA ISH using type-specific HPV DNA probes (HPV 6, 11, 16, 18, 31, 33). Separate analyses were conducted comparing viral types, frequency of recurrences and duration of disease-free periods. RESULTS: We detected HPV DNA in 40 of the 70 laryngeal papilloma cases (57%). In particular, HPV DNA was detected in 75% of the juvenile types. There were significant associations between HPV and laryngeal papilloma (p<0.01). Among the HPV-positive cases, major specific types were HPV 6/11 (97%). Significant associations were also noted between viral expression and clinical course. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1138~1144 | - |
dc.relation.isPartOf | ACTA OTO-LARYNGOLOGICA | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Child | - |
dc.subject.MESH | DNA Probes | - |
dc.subject.MESH | DNA, Viral/genetics | - |
dc.subject.MESH | Disease-Free Survival | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | In Situ Hybridization | - |
dc.subject.MESH | Laryngeal Neoplasms/mortality | - |
dc.subject.MESH | Laryngeal Neoplasms/pathology | - |
dc.subject.MESH | Laryngeal Neoplasms/virology* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Neoplasm Recurrence, Local/virology | - |
dc.subject.MESH | Papilloma/mortality | - |
dc.subject.MESH | Papilloma/pathology | - |
dc.subject.MESH | Papilloma/virology* | - |
dc.subject.MESH | Papillomaviridae/isolation & purification | - |
dc.subject.MESH | Papillomavirus Infections/virology* | - |
dc.subject.MESH | Remission Induction | - |
dc.subject.MESH | Retrospective Studies | - |
dc.title | Effect of human papilloma virus expression on clinical course of laryngeal papilloma | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Otorhinolaryngology (이비인후과학) | - |
dc.contributor.googleauthor | Kim KM | - |
dc.contributor.googleauthor | Cho NH | - |
dc.contributor.googleauthor | Choi HS | - |
dc.contributor.googleauthor | Kim YH | - |
dc.contributor.googleauthor | Byeon HK | - |
dc.contributor.googleauthor | Min HJ | - |
dc.contributor.googleauthor | Kim SH. | - |
dc.identifier.doi | 10.1080/00016480701827509 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00313 | - |
dc.contributor.localId | A00605 | - |
dc.contributor.localId | A00731 | - |
dc.contributor.localId | A03812 | - |
dc.contributor.localId | A04223 | - |
dc.relation.journalcode | J00028 | - |
dc.identifier.eissn | 1651-2251 | - |
dc.identifier.pmid | 18607996 | - |
dc.identifier.url | http://informahealthcare.com/doi/abs/10.1080/00016480701827509 | - |
dc.subject.keyword | Laryngeal papilloma | - |
dc.subject.keyword | in situ hybridization | - |
dc.subject.keyword | human papilloma virus | - |
dc.contributor.alternativeName | Kim, Kwang Moon | - |
dc.contributor.alternativeName | Kim, Se Heon | - |
dc.contributor.alternativeName | Kim, Young Ho | - |
dc.contributor.alternativeName | Cho, Nam Hoon | - |
dc.contributor.alternativeName | Choi, Hong Shik | - |
dc.contributor.affiliatedAuthor | Kim, Kwang Moon | - |
dc.contributor.affiliatedAuthor | Kim, Se Heon | - |
dc.contributor.affiliatedAuthor | Kim, Young Ho | - |
dc.contributor.affiliatedAuthor | Cho, Nam Hoon | - |
dc.contributor.affiliatedAuthor | Choi, Hong Shik | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 128 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 1138 | - |
dc.citation.endPage | 1144 | - |
dc.identifier.bibliographicCitation | ACTA OTO-LARYNGOLOGICA, Vol.128(10) : 1138-1144, 2008 | - |
dc.identifier.rimsid | 35233 | - |
dc.type.rims | ART | - |
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