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성기 부위와 성기외 부위 경화 위축성 태선의 임상적, 조직학적 비교

DC FieldValueLanguage
dc.contributor.author오상호-
dc.contributor.author이광훈-
dc.contributor.author이주희-
dc.date.accessioned2015-05-19T17:25:19Z-
dc.date.available2015-05-19T17:25:19Z-
dc.date.issued2008-
dc.identifier.issn4944-4739-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/108116-
dc.description.abstractBackground: Lichen sclerosus et atrophicus is a persistent inflammatory dermatosis of unknown etiology with a predilection for the genital area. Although there were many case reports in Korea, there are no studies regarding the clinicopathologic comparison of genital and extragenital lichen sclerosus et atrophicus. Objective: The aim of our study was to evaluate the clinicopathologic characteristics and differences between genital and extragenital lichen sclerosus et atrophicus. Methods: Retrospective analysis was performed by reviewing the clinicopatholgic records of 33 patients who were diagnosed with lichen sclerosus et atrophicus from 2000 to 2006 in Yonsei University Severance Hospital. Results: The most common clinical manifestation is a whitish patch with pruritus on labia minor. The ratio of male to female patients in genital and extragenital lichen sclerosus et atrophicus were 1:10.5 and 1:2.3 respectively. Disease onset ages were 49.9 years and 44.2 years respectively. The most common subjective symptom was pruritus. However, no symptom was more significant in extragenital lichen sclerosus et atrophicus compared to genital lichen sclerosus et atrophicus. Most of the lesions presented as whitish patches and plaques but atrophy, erythema and lichenification could also occur. Histopathologic findings of the extragenital lichen sclerosus et atrophicus showed more significant epidermal thinning and cleft formation compared to genital lichen sclerosus et atrophicus, which suggests that extragenital lichen sclerosus et atrophicus shows more evolved lesions. A few cases of genital lichen sclerosus et atrophicus showed spongiotic dermatitis, lichen simplex chronicus-like and lichen planus-like features in addition to typical pathology, which were suspected as secondary features or early lesions. All the patients were treated with high to mid-potency topical corticosteroid which were effective in both the genital and extragenital lichen sclerosus et atrophicus. There was no cases of squamous cell carcinoma arising in lichen sclerosus et atrophicus during the follow-up. Conclusion: Clinically, there were no symptoms significant to extragenital lichen sclerosus et atrophicus and pathologically extragenital lichen sclerosus et atrophicus showed more significant epidermal thinning and cleft formation. Further research regarding the characteristics and differences between genital and extragenital lichen sclerosus et atrophicus should be performed on larger number of cases-
dc.description.statementOfResponsibilityopen-
dc.format.extent633~640-
dc.relation.isPartOfKorean Journal of Dermatology (대한피부과학회지)-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.title성기 부위와 성기외 부위 경화 위축성 태선의 임상적, 조직학적 비교-
dc.title.alternativeClinicopathologic Comparison of Genital and Extragenital Lichen Sclerosus et Atrophicus-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Dermatology (피부과학)-
dc.contributor.googleauthor오상호-
dc.contributor.googleauthor류동진-
dc.contributor.googleauthor이광훈-
dc.contributor.googleauthor이주희-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02370-
dc.contributor.localIdA03171-
dc.contributor.localIdA02674-
dc.relation.journalcodeJ02000-
dc.identifier.pmidWords; Extragenital lichen sclerosus et atrophicus; Genital-
dc.subject.keywordWords-
dc.subject.keywordExtragenital lichen sclerosus et atrophicus-
dc.subject.keywordGenital-
dc.contributor.alternativeNameOh, Sang Ho-
dc.contributor.alternativeNameLee, Kwang Hoon-
dc.contributor.alternativeNameLee, Ju Hee-
dc.contributor.affiliatedAuthorOh, Sang Ho-
dc.contributor.affiliatedAuthorLee, Ju Hee-
dc.contributor.affiliatedAuthorLee, Kwang Hoon-
dc.rights.accessRightsfree-
dc.citation.volume46-
dc.citation.number5-
dc.citation.startPage633-
dc.citation.endPage640-
dc.identifier.bibliographicCitationKorean Journal of Dermatology (대한피부과학회지), Vol.46(5) : 633-640, 2008-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers

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