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Comparison of remifentanil and fentanyl for postoperative pain control after abdominal hysterectomy

DC FieldValueLanguage
dc.contributor.author남순호-
dc.contributor.author이기영-
dc.contributor.author이성진-
dc.contributor.author최승호-
dc.contributor.author구본녀-
dc.contributor.author길혜금-
dc.contributor.author김기준-
dc.date.accessioned2015-05-19T17:25:07Z-
dc.date.available2015-05-19T17:25:07Z-
dc.date.issued2008-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/108110-
dc.description.abstractPURPOSE: In this randomized, double-blind study, we investigated the analgesic efficacy and side effects of continuous constant-dose infusions of remifentanil after total abdominal hysterectomy and compared it to fentanyl. MATERIALS AND METHODS: Fifty-six adult female patients scheduled for elective total abdominal hysterectomy were enrolled in this study. Patients were randomly assigned to two groups according to fentanyl (group F, n=28) or remifentanil (group R, n=28) for postoperative analgesia. Patients in group F were given fentanyl intravenously with an infusion rate of fentanyl 0.5 microg/kg/hr; group R was given remifentanil with an infusion rate of remifentanil 0.05 microg/kg/min for 2 days. Pain intensity at rest, occurrence of postoperative nausea and vomiting (PONV), dizziness, pruritus, and respiratory depression were assessed 1 hr after arrival at the post-anesthesia care unit, at 6; 12; 24; and 48 hr post-operation and 6 hr post-infusion of the study drug. Pain was evaluated by using visual analogue scale (VAS; 0-10). The time that patients first requested analgesics was recorded as well as additional analgesics and antiemetics. RESULTS: There were no significant differences in VAS, time to first postoperative analgesics, and additional analgesics between the 2 groups. The incidences and severities of PONV and opioid related side effects were not different between the groups; however, there were 3 episodes (10.7%) of serious respiratory depression in group R. CONCLUSION: Continuous infusion technique of remifentanil did not reveal any benefits compared to fentanyl. Furthermore, it is not safe for postoperative analgesia in the general ward.-
dc.description.statementOfResponsibilityopen-
dc.format.extent204~210-
dc.relation.isPartOfYonsei Medical Journal-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdolescent-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAnalgesics, Opioid/administration & dosage-
dc.subject.MESHAnalgesics, Opioid/therapeutic use-
dc.subject.MESHDrug Administration Schedule-
dc.subject.MESHFemale-
dc.subject.MESHFentanyl/administration & dosage-
dc.subject.MESHFentanyl/therapeutic use*-
dc.subject.MESHHumans-
dc.subject.MESHHysterectomy/adverse effects*-
dc.subject.MESHInfusions, Intravenous-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPain, Postoperative/drug therapy*-
dc.subject.MESHPain, Postoperative/etiology-
dc.subject.MESHPiperidines/administration & dosage-
dc.subject.MESHPiperidines/therapeutic use*-
dc.subject.MESHRemifentanil-
dc.subject.MESHTreatment Outcome-
dc.titleComparison of remifentanil and fentanyl for postoperative pain control after abdominal hysterectomy-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Anesthesiology (마취통증의학)-
dc.contributor.googleauthorSeung Ho Choi-
dc.contributor.googleauthorBon-Nyeo Koo-
dc.contributor.googleauthorSoon Ho Nam-
dc.contributor.googleauthorSung Jin Lee-
dc.contributor.googleauthorKi Jun Kim-
dc.contributor.googleauthorHae Keum Kil-
dc.contributor.googleauthorKi-Young Lee-
dc.contributor.googleauthorDong Hyuk Jeon-
dc.identifier.doi10.3349/ymj.2008.49.2.204-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01256-
dc.contributor.localIdA02695-
dc.contributor.localIdA02872-
dc.contributor.localIdA00193-
dc.contributor.localIdA00283-
dc.contributor.localIdA00340-
dc.contributor.localIdA04101-
dc.relation.journalcodeJ02813-
dc.identifier.pmid18452255-
dc.subject.keywordAdolescent-
dc.subject.keywordAdult-
dc.subject.keywordAged-
dc.subject.keywordAnalgesics, Opioid/administration & dosage-
dc.subject.keywordAnalgesics, Opioid/therapeutic use-
dc.subject.keywordDrug Administration Schedule-
dc.subject.keywordFemale-
dc.subject.keywordFentanyl/administration & dosage-
dc.subject.keywordFentanyl/therapeutic use*-
dc.subject.keywordHumans-
dc.subject.keywordHysterectomy/adverse effects*-
dc.subject.keywordInfusions, Intravenous-
dc.subject.keywordMiddle Aged-
dc.subject.keywordPain, Postoperative/drug therapy*-
dc.subject.keywordPain, Postoperative/etiology-
dc.subject.keywordPiperidines/administration & dosage-
dc.subject.keywordPiperidines/therapeutic use*-
dc.subject.keywordRemifentanil-
dc.subject.keywordTreatment Outcome-
dc.contributor.alternativeNameNam, Soon Ho-
dc.contributor.alternativeNameLee, Ki Young-
dc.contributor.alternativeNameLee, Sung Jin-
dc.contributor.alternativeNameChoi, Seung Ho-
dc.contributor.alternativeNameKu, Bon Nyo-
dc.contributor.alternativeNameKil, Hae Keum-
dc.contributor.alternativeNameKim, Ki Jun-
dc.contributor.affiliatedAuthorNam, Soon Ho-
dc.contributor.affiliatedAuthorLee, Ki Young-
dc.contributor.affiliatedAuthorLee, Sung Jin-
dc.contributor.affiliatedAuthorKu, Bon Nyo-
dc.contributor.affiliatedAuthorKil, Hae Keum-
dc.contributor.affiliatedAuthorKim, Ki Jun-
dc.contributor.affiliatedAuthorChoi, Seung Ho-
dc.rights.accessRightsfree-
dc.citation.volume49-
dc.citation.number1-
dc.citation.startPage204-
dc.citation.endPage210-
dc.identifier.bibliographicCitationYonsei Medical Journal, Vol.49(1) : 204-210, 2008-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers

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