Cited 42 times in
Evaluation of metabolic syndrome risk in Korean premenopausal women: not waist circumference but visceral fat.
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 장양수 | - |
dc.contributor.author | 하종원 | - |
dc.date.accessioned | 2015-05-19T17:22:04Z | - |
dc.date.available | 2015-05-19T17:22:04Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 1346-9843 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/108012 | - |
dc.description.abstract | BACKGROUND: In clinical practice, using the patient's waist circumference (WC) to evaluate visceral obesity may underestimate disorders with a metabolic origin. This study examined whether or not the WC derived from the cut-off point of the visceral fat area (VFA) can reflect the features of metabolic syndrome (MetS) in premenopausal women. METHODS AND RESULTS: Computed tomography-scanned VFA, MetS components and the concentrations of high-sensitivity C-reactive protein (CRP) and adiponectin were measured in a total of 349 premenopausal women. The VFA at the L1 and the L4 sites was a significant index (p<0.001) of incremental MetS risk. Receiver-operating characteristic curve analysis showed that 75 cm2 of VFA at L4 and 87.5 cm2 at L1 were the optimal thresholds for discrimination of MetS risk. Significant differences in all MetS components, as well as CRP (p<0.05) and adiponectin levels (p<0.005), were observed when subjects were subdivided by the L4 VFA cut-off point (<75/>or=75 cm2), whereas there was a significant difference only in the triglycerides level in the groups divided by WC (WC<88/>or=88 cm). Moreover, subjects with a lower WC-higher VFA showed a similar pattern in MetS components and lower adiponectin than those with a higher WC-higher VFA. CONCLUSIONS: This study clarified that VFA rather than WC is a major determinant of MetS risk in premenopausal women | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1308~1315 | - |
dc.relation.isPartOf | CIRCULATION JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adiponectin/blood | - |
dc.subject.MESH | Adiposity* | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Asian Continental Ancestry Group* | - |
dc.subject.MESH | Biomarkers/blood | - |
dc.subject.MESH | Body Mass Index | - |
dc.subject.MESH | Body Size | - |
dc.subject.MESH | C-Reactive Protein/metabolism | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Intra-Abdominal Fat/diagnostic imaging | - |
dc.subject.MESH | Intra-Abdominal Fat/metabolism | - |
dc.subject.MESH | Intra-Abdominal Fat/pathology* | - |
dc.subject.MESH | Korea | - |
dc.subject.MESH | Linear Models | - |
dc.subject.MESH | Lipids/blood | - |
dc.subject.MESH | Metabolic Syndrome/ethnology | - |
dc.subject.MESH | Metabolic Syndrome/etiology* | - |
dc.subject.MESH | Metabolic Syndrome/metabolism | - |
dc.subject.MESH | Metabolic Syndrome/pathology | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Premenopause* | - |
dc.subject.MESH | ROC Curve | - |
dc.subject.MESH | Risk Assessment | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Tomography, X-Ray Computed | - |
dc.title | Evaluation of metabolic syndrome risk in Korean premenopausal women: not waist circumference but visceral fat. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Yae Jung Hyun | - |
dc.contributor.googleauthor | Oh Yoen Kim | - |
dc.contributor.googleauthor | Yangsoo Jang | - |
dc.contributor.googleauthor | Jong-Won Ha | - |
dc.contributor.googleauthor | Jey Sook Chae | - |
dc.contributor.googleauthor | Ji Young Kim | - |
dc.contributor.googleauthor | Hyun Yang Yeo | - |
dc.contributor.googleauthor | Jean Kyung Paik | - |
dc.contributor.googleauthor | Jong Ho Lee | - |
dc.identifier.doi | 10.1253/circj.72.1308 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03448 | - |
dc.contributor.localId | A04257 | - |
dc.relation.journalcode | J00534 | - |
dc.identifier.eissn | 1347-4820 | - |
dc.identifier.pmid | 18654019 | - |
dc.subject.keyword | Metabolic syndrome | - |
dc.subject.keyword | Premenopausal women | - |
dc.subject.keyword | Visceral fat | - |
dc.subject.keyword | Waist circumference | - |
dc.contributor.alternativeName | Jang, Yang Soo | - |
dc.contributor.alternativeName | Ha, Jong Won | - |
dc.contributor.affiliatedAuthor | Jang, Yang Soo | - |
dc.contributor.affiliatedAuthor | Ha, Jong Won | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 72 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 1308 | - |
dc.citation.endPage | 1315 | - |
dc.identifier.bibliographicCitation | CIRCULATION JOURNAL, Vol.72(8) : 1308-1315, 2008 | - |
dc.identifier.rimsid | 50064 | - |
dc.type.rims | ART | - |
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