79 202

Cited 0 times in

Utility of QuantiFERON-TB In-Tube Test for Differentiating Active Tuberculosis from Latent Tuberculosis Infection in an Intermediate Burden Country

DC FieldValueLanguage
dc.contributor.author김명수-
dc.contributor.author김준명-
dc.contributor.author김창오-
dc.contributor.author송영구-
dc.contributor.author이한성-
dc.contributor.author정수진-
dc.contributor.author진범식-
dc.contributor.author최석훈-
dc.contributor.author최준용-
dc.contributor.author최희경-
dc.contributor.author한상훈-
dc.date.accessioned2015-05-19T17:21:32Z-
dc.date.available2015-05-19T17:21:32Z-
dc.date.issued2008-
dc.identifier.issn1598-8112-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/107996-
dc.description.abstractBACKGROUND: The aim of the present study was to assess the contribution of a QuantiFERON-TB Gold In-Tube test (QFT-IT) in differentiating active tuberculosis (TB) from latent tuberculosis infection (LTBI) by quantifying interferon-gamma levels. MATERIALS AND METHODS: We retrospectively reviewed clinical records of 314 patients older than 15 years who had performed QFT-IT between July 2006 and August 2007 at a tertiary care teaching hospital. RESULTS: Subjects with active TB (n=81, culture confirmed active TB in 40 subjects) and LTBI (n=76) were included. Mean+/-SD IFN-gamma levels were 4.96+/-3.98 IU/mL (range -0.08-10) for all subjects with active TB, 4.54+/-4.05 IU/mL (range -0.08-10) for culture confirmed active TB, and 4.11+/-3.57 IU/mL (range 0.35-10) for subjects with LTBI. The quantitative results of QFT-IT on IFN-gamma levels between all the subjects with active TB and those with LTBI were not statistically significant (P=0.16). The result was similar when compared between those with culture confirmed active TB and those with LTBI, showing little statistical significance (P=0.554). CONCLUSION: The production of IFN-gamma measured by QFT-IT showed no correlation between its level and the activity of Mycobacterium tuberculosis infection. These results suggest that measuring IFN-gamma using QFT-IT might not be useful for distinguishing active TB from LTBI-
dc.description.statementOfResponsibilityopen-
dc.format.extent305~310-
dc.relation.isPartOfInfection and Chemotherapy-
dc.relation.isPartOf감염과 화학요법-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleUtility of QuantiFERON-TB In-Tube Test for Differentiating Active Tuberculosis from Latent Tuberculosis Infection in an Intermediate Burden Country-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorSuk Hoon Choi-
dc.contributor.googleauthorBum Sik Chin-
dc.contributor.googleauthorSang Hoon Han-
dc.contributor.googleauthorHan Sung Lee-
dc.contributor.googleauthorChang Oh Kim-
dc.contributor.googleauthorSu Jin Jeong-
dc.contributor.googleauthorHee Kyung Choi-
dc.contributor.googleauthorMyung Soo Kim-
dc.contributor.googleauthorJun Yong Choi-
dc.contributor.googleauthorYoung Goo Song-
dc.contributor.googleauthorJune Myung Kim-
dc.identifier.doi10.3947/ic.2008.40.6.305-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00953-
dc.contributor.localIdA01044-
dc.contributor.localIdA02037-
dc.contributor.localIdA03277-
dc.contributor.localIdA03638-
dc.contributor.localIdA03981-
dc.contributor.localIdA04071-
dc.contributor.localIdA04191-
dc.contributor.localIdA04228-
dc.contributor.localIdA04286-
dc.contributor.localIdA00423-
dc.relation.journalcodeJ01054-
dc.contributor.alternativeNameKim, Myoung Soo-
dc.contributor.alternativeNameKim, June Myung-
dc.contributor.alternativeNameKim, Chang Oh-
dc.contributor.alternativeNameSong, Young Goo-
dc.contributor.alternativeNameLee, Han Sung-
dc.contributor.alternativeNameJeong, Su Jin-
dc.contributor.alternativeNameChin, Bum Sik-
dc.contributor.alternativeNameChoi, Suk Hoon-
dc.contributor.alternativeNameChoi, Jun Yong-
dc.contributor.alternativeNameChoi, Hee Kyoung-
dc.contributor.alternativeNameHan, Sang Hoon-
dc.contributor.affiliatedAuthorKim, June Myung-
dc.contributor.affiliatedAuthorKim, Chang Oh-
dc.contributor.affiliatedAuthorSong, Young Goo-
dc.contributor.affiliatedAuthorLee, Han Sung-
dc.contributor.affiliatedAuthorJeong, Su Jin-
dc.contributor.affiliatedAuthorChin, Bum Sik-
dc.contributor.affiliatedAuthorChoi, Suk Hoon-
dc.contributor.affiliatedAuthorChoi, Jun Yong-
dc.contributor.affiliatedAuthorChoi, Hee Kyoung-
dc.contributor.affiliatedAuthorHan, Sang Hoon-
dc.contributor.affiliatedAuthorKim, Myoung Soo-
dc.rights.accessRightsfree-
dc.citation.volume40-
dc.citation.number6-
dc.citation.startPage305-
dc.citation.endPage310-
dc.identifier.bibliographicCitationInfection and Chemotherapy (감염과 화학요법), Vol.40(6) : 305-310, 2008-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.