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A case of black thyroid associated with hyalinizing trabecular tumor

DC Field Value Language
dc.contributor.author강상욱-
dc.contributor.author남기현-
dc.contributor.author성태연-
dc.contributor.author이승철-
dc.contributor.author이용상-
dc.contributor.author장항석-
dc.contributor.author정웅윤-
dc.contributor.author정종주-
dc.contributor.author홍순원-
dc.date.accessioned2015-05-19T17:18:15Z-
dc.date.available2015-05-19T17:18:15Z-
dc.date.issued2008-
dc.identifier.issn0918-8959-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/107891-
dc.description.abstractBlack thyroid is an uncommon phenomenon of black pigmentation of thyroid parenchyma induced by chronic minocycline therapy. Thyroid tumors associated with black pigmented thyroid are rare. We describe here a 42-year-old woman with a black thyroid associated with hyalinizing trabecular tumor (HTT). The patient presented with a palpable left-sided thyroid nodule. She had taken minocycline for aphthous stomatitis and an oral ulcer for 9 years. The findings of fine needle aspiration biopsy and BRAF mutation analysis suggested a papillary carcinoma. The patient underwent a near-total thyroidectomy with central compartment node dissection. The surgical specimen showed a diffuse black thyroid and a 2-cm non-pigmented, well-circumscribed nodule in the left thyroid. Histopathologically, numerous black pigmented follicular epithelial cells and colloid were seen throughout the thyroid parenchyma, and the nodule was composed of elongated, polygonal cells in trabecular arrangement and dense hyaline stromas. The tumor cells showed a strong positive cytoplasmic reaction to Ki 67. All of these findings suggested a HTT, or a hyalinizing trabecular variant of papillary carcinoma, arising in a black thyroid. To our knowledge, this is the first case of black thyroid associated with HTT-
dc.description.statementOfResponsibilityopen-
dc.format.extent1109~1112-
dc.relation.isPartOfENDOCRINE JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdenoma/diagnosis*-
dc.subject.MESHAdenoma/metabolism-
dc.subject.MESHAdenoma/physiopathology-
dc.subject.MESHAdult-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHHyalin/metabolism-
dc.subject.MESHPigmentation/physiology*-
dc.subject.MESHThyroid Gland/physiopathology*-
dc.subject.MESHThyroid Neoplasms/diagnosis*-
dc.subject.MESHThyroid Neoplasms/metabolism-
dc.subject.MESHThyroid Neoplasms/physiopathology-
dc.titleA case of black thyroid associated with hyalinizing trabecular tumor-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pathology (병리학)-
dc.contributor.googleauthorSang-Wook KANG-
dc.contributor.googleauthorSoon Won HONG-
dc.contributor.googleauthorPyo Ju YEON-
dc.contributor.googleauthorJong Ju JEONG-
dc.contributor.googleauthorTae Yon SUNG-
dc.contributor.googleauthorSeung Chul LEE-
dc.contributor.googleauthorYong Sang LEE-
dc.contributor.googleauthorKee-Hyun NAM-
dc.contributor.googleauthorWoong Youn CHUNG-
dc.contributor.googleauthorHang Seok CHANG-
dc.contributor.googleauthorCheong Soo PARK-
dc.identifier.doi18753707-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02929-
dc.contributor.localIdA00032-
dc.contributor.localIdA01245-
dc.contributor.localIdA01957-
dc.contributor.localIdA02978-
dc.contributor.localIdA03488-
dc.contributor.localIdA03674-
dc.contributor.localIdA03722-
dc.contributor.localIdA04411-
dc.relation.journalcodeJ00769-
dc.identifier.eissn1348-4540-
dc.identifier.pmid18753707-
dc.subject.keywordBlack thyroid-
dc.subject.keywordHyalinizing trabecular tumor-
dc.subject.keywordMinocycline-
dc.contributor.alternativeNameKang, Sang Wook-
dc.contributor.alternativeNameNam, Kee Hyun-
dc.contributor.alternativeNameSung, Tae Yon-
dc.contributor.alternativeNameLee, Seung Chul-
dc.contributor.alternativeNameLee, Yong Sang-
dc.contributor.alternativeNameChang, Hang Seok-
dc.contributor.alternativeNameChung, Woung Youn-
dc.contributor.alternativeNameJeong, Jong Ju-
dc.contributor.alternativeNameHong, Soon Won-
dc.contributor.affiliatedAuthorLee, Seung Chul-
dc.contributor.affiliatedAuthorKang, Sang Wook-
dc.contributor.affiliatedAuthorNam, Kee Hyun-
dc.contributor.affiliatedAuthorSung, Tae Yon-
dc.contributor.affiliatedAuthorLee, Yong Sang-
dc.contributor.affiliatedAuthorChang, Hang Seok-
dc.contributor.affiliatedAuthorChung, Woung Youn-
dc.contributor.affiliatedAuthorJeong, Jong Ju-
dc.contributor.affiliatedAuthorHong, Soon Won-
dc.rights.accessRightsfree-
dc.citation.volume55-
dc.citation.number6-
dc.citation.startPage1109-
dc.citation.endPage1112-
dc.identifier.bibliographicCitationENDOCRINE JOURNAL, Vol.55(6) : 1109-1112, 2008-
dc.identifier.rimsid34758-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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