Cited 21 times in
Bone metabolism in postmenopausal women with lumbar spinal stenosis: analysis of bone mineral density and bone turnover markers
DC Field | Value | Language |
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dc.contributor.author | 김학선 | - |
dc.contributor.author | 김호중 | - |
dc.contributor.author | 문성환 | - |
dc.contributor.author | 문은수 | - |
dc.contributor.author | 박진오 | - |
dc.contributor.author | 이환모 | - |
dc.date.accessioned | 2015-05-19T17:13:30Z | - |
dc.date.available | 2015-05-19T17:13:30Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 0362-2436 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/107740 | - |
dc.description.abstract | STUDY DESIGN: A cross-sectional study. OBJECTIVE: To investigate bone mineral density (BMD) and the change of bone turnover rate in postmenopausal women with lumbar spinal stenosis (LSS). SUMMARY OF BACKGROUND DATA: Symptomatic LSS prevents elderly patients from performing daily activities because of back pain and neurogenic claudication. Walking intolerance due to neurologic claudication might have a negative effect on bone metabolism and BMD. However, there has been no study on the relationship between LSS and bone metabolism, especially on bone turnover rate. METHODS: Sixty-seven patients were in the LSS group. As a control group, 67 age- and weight-matched subjects were selected. In both groups, BMD, bone turnover markers, vitamin D, severity of knee osteoarthritis, and demographic data were obtained. In the LSS group, walking distance without rest was also recorded. BMD, bone turnover markers, vitamin D, and severity of knee osteoarthritis were compared between the two groups. In the LSS group, the correlation between walking intolerance and bone turnover markers was also analyzed. RESULTS: In the LSS group, urinary N-terminal telopeptide of type I collagen (u-NTx) and alkaline phosphatase were significantly elevated when compared with those of the control group (P < 0.05). However, BMD was significantly low in the control group in all of the measured sites (P < 0.05). In the LSS group, neither bone markers nor BMD were correlated with the extent of walking difficulty. CONCLUSION: Our study highlights the fact that limited physical activity results in high bone turnover rate in patients with LSS | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 2435~2439 | - |
dc.relation.isPartOf | SPINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Alkaline Phosphatase/urine | - |
dc.subject.MESH | Bone Density* | - |
dc.subject.MESH | Bone Remodeling* | - |
dc.subject.MESH | Case-Control Studies | - |
dc.subject.MESH | Collagen/urine | - |
dc.subject.MESH | Cross-Sectional Studies | - |
dc.subject.MESH | Exercise Tolerance | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Intermittent Claudication/physiopathology | - |
dc.subject.MESH | Lumbar Vertebrae* | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Mobility Limitation | - |
dc.subject.MESH | Osteoarthritis, Knee/physiopathology | - |
dc.subject.MESH | Postmenopause* | - |
dc.subject.MESH | Spinal Stenosis/metabolism | - |
dc.subject.MESH | Spinal Stenosis/physiopathology* | - |
dc.subject.MESH | Vitamin D Deficiency/physiopathology | - |
dc.subject.MESH | Walking | - |
dc.title | Bone metabolism in postmenopausal women with lumbar spinal stenosis: analysis of bone mineral density and bone turnover markers | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Orthopedic Surgery (정형외과학) | - |
dc.contributor.googleauthor | Ho-Joong Kim | - |
dc.contributor.googleauthor | Hwan-Mo Lee | - |
dc.contributor.googleauthor | Hak-Sun Kim | - |
dc.contributor.googleauthor | Jin-Oh Park | - |
dc.contributor.googleauthor | Eun-Su Moon | - |
dc.contributor.googleauthor | Hoon Park | - |
dc.contributor.googleauthor | Si-Young Park | - |
dc.contributor.googleauthor | Seong-Hwan Moon | - |
dc.identifier.doi | 10.1097/BRS.0b013e3181829fca | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01186 | - |
dc.contributor.localId | A01093 | - |
dc.contributor.localId | A01365 | - |
dc.contributor.localId | A01372 | - |
dc.contributor.localId | A01703 | - |
dc.contributor.localId | A03333 | - |
dc.relation.journalcode | J02674 | - |
dc.identifier.eissn | 1528-1159 | - |
dc.identifier.pmid | 18923320 | - |
dc.identifier.url | http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00007632-200810150-00012&LSLINK=80&D=ovft | - |
dc.subject.keyword | spinal stenosis | - |
dc.subject.keyword | bone turnover rate | - |
dc.subject.keyword | bone turnover marker | - |
dc.subject.keyword | bone mineral density | - |
dc.contributor.alternativeName | Kim, Hak Sun | - |
dc.contributor.alternativeName | Kim, Ho Joong | - |
dc.contributor.alternativeName | Moon, Seong Hwan | - |
dc.contributor.alternativeName | Moon, Eun Su | - |
dc.contributor.alternativeName | Park, Jin Oh | - |
dc.contributor.alternativeName | Lee, Hwan Mo | - |
dc.contributor.affiliatedAuthor | Kim, Ho Joong | - |
dc.contributor.affiliatedAuthor | Kim, Hak Sun | - |
dc.contributor.affiliatedAuthor | Moon, Seong Hwan | - |
dc.contributor.affiliatedAuthor | Moon, Eun Su | - |
dc.contributor.affiliatedAuthor | Park, Jin Oh | - |
dc.contributor.affiliatedAuthor | Lee, Hwan Mo | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 33 | - |
dc.citation.number | 22 | - |
dc.citation.startPage | 2435 | - |
dc.citation.endPage | 2439 | - |
dc.identifier.bibliographicCitation | SPINE, Vol.33(22) : 2435-2439, 2008 | - |
dc.identifier.rimsid | 55295 | - |
dc.type.rims | ART | - |
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