1 166

Cited 0 times in

Interactive effect of central obesity and hypertension on cognitive function in older out-patients with Type 2 diabetes

 E. Kim  ;  M. H. Cho  ;  K. R. Cha  ;  J. S. Park  ;  C-W. Ahn  ;  B. H. Oh  ;  C-H. Kim 
 Diabetic Medicine, Vol.25(12) : 1440-1446, 2008 
Journal Title
 Diabetic Medicine 
Issue Date
AIM: Central obesity, hypertension and diabetes mellitus have been related individually to cognitive dysfunction. We aimed to study the interactive effects of these co-occurring risk factors on cognitive decline, which remain unclear in older patients with diabetes. METHODS: We assessed metabolic profiles and neuropsychological functions in 60 older out-patients with Type 2 diabetes to examine the associations of central obesity with cognitive functions, while controlling for other confounding factors in these subjects. RESULTS: Waist circumference was associated with poor performance in digits forward (r2 = 0.11, P = 0.02), choice reaction time (r2 = 0.08, P = 0.04) and cognitive reaction time (r2 = 0.07, P < 0.05) even after adjustment for potential confounders including age, gender, education and HbA1c. There were also significant interactions between central obesity and hypertension with respect to performance of digits forward (P = 0.04) and delayed verbal cued recall (P = 0.03). CONCLUSION: Our findings suggest that, in addition to glycaemic control, central obesity and hypertension influence cognitive functions, such as attention and psychomotor speed in older patients with Type 2 diabetes.
Full Text
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
김어수(Kim, Eosu) ORCID logo https://orcid.org/0000-0001-9472-9465
김찬형(Kim, Chan Hyung)
박종숙(Park, Jong Suk) ORCID logo https://orcid.org/0000-0002-5385-1373
안철우(Ahn, Chul Woo) ORCID logo https://orcid.org/0000-0003-3733-7486
오병훈(Oh, Byong Hoon)
조민호(Cho, Min Ho)
RIS (EndNote)
XLS (Excel)
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.