Cited 26 times in
Phenotypic spectrum and clinical characteristics of apical hypertrophic cardiomyopathy: multicenter echo-Doppler study
DC Field | Value | Language |
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dc.contributor.author | 정남식 | - |
dc.contributor.author | 최의영 | - |
dc.contributor.author | 하종원 | - |
dc.contributor.author | 임세중 | - |
dc.date.accessioned | 2015-05-19T17:11:02Z | - |
dc.date.available | 2015-05-19T17:11:02Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 0008-6312 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/107660 | - |
dc.description.abstract | OBJECTIVES: The aim of this study was to define the phenotypic spectrum of apical hypertrophic cardiomyopathy (ApHCM) and clinical characteristics pertaining to identified subtypes. METHODS: In 182 consecutive ApHCM patients (58.9 +/- 11.2 years; 142 men) with left ventricular ejection fraction > or =50%, we measured end-diastolic wall thickness of all 16 left ventricular segments to determine patterns of hypertrophy. Echo-Doppler parameters, electrocardiography patterns, and clinical findings were analyzed. RESULTS: ApHCM was classified into three types as pure focal (n = 81), pure diffuse (n = 70) and mixed type (n = 31) according to patterns of hypertrophy. Incidence of atrial fibrillation (5% for pure focal vs. 11% for pure diffuse vs. 23% for mixed type, p < 0.05) and left atrial volume index (30.9 +/- 11.8, 35.7 +/- 14.8, and 41.3 +/- 15.9 ml/m(2), respectively, p < 0.001) were significantly different among subtypes. Peak systolic (6.6 +/- 1.0 vs. 6.3 +/- 1.2 vs. 5.9 +/- 1.1 cm/s, respectively, p < 0.05), diastolic (5.1 +/- 1.8 vs. 5.0 +/- 1.2 vs. 4.1 +/- 1.3 cm/s, respectively, p < 0.05) mitral annular velocity, E/E' (13.3 +/- 4.2 vs. 13.7 +/- 5.4 vs. 16.1 +/- 6.1, respectively, p < 0.05) were also significantly different. CONCLUSIONS: ApHCM contains three morphologically distinct phenotypes and detailed subtyping is important in the prediction of development of atrial fibrillation, left atrial volume index and left ventricular longitudinal function. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 53~61 | - |
dc.relation.isPartOf | CARDIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Age Factors | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Analysis of Variance | - |
dc.subject.MESH | Cardiomyopathy, Hypertrophic/diagnostic imaging* | - |
dc.subject.MESH | Cardiomyopathy, Hypertrophic/genetics* | - |
dc.subject.MESH | Cardiomyopathy, Hypertrophic/physiopathology | - |
dc.subject.MESH | Echocardiography, Doppler | - |
dc.subject.MESH | Electrocardiography | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Genetic Predisposition to Disease* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Linear Models | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Phenotype* | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Risk Assessment | - |
dc.subject.MESH | Severity of Illness Index | - |
dc.subject.MESH | Sex Factors | - |
dc.subject.MESH | Stroke Volume | - |
dc.title | Phenotypic spectrum and clinical characteristics of apical hypertrophic cardiomyopathy: multicenter echo-Doppler study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Eui-Young Choi | - |
dc.contributor.googleauthor | Se-Joong Rim | - |
dc.contributor.googleauthor | Jong-Won Ha | - |
dc.contributor.googleauthor | Yong-Jin Kim | - |
dc.contributor.googleauthor | Sang-Chol Lee | - |
dc.contributor.googleauthor | Duk-Hyun Kang | - |
dc.contributor.googleauthor | Seung Woo Park | - |
dc.contributor.googleauthor | Jae-Kwan Song | - |
dc.contributor.googleauthor | Dae-Won Sohn | - |
dc.contributor.googleauthor | Namsik Chung | - |
dc.identifier.doi | 10.1159/000109407 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03585 | - |
dc.contributor.localId | A04165 | - |
dc.contributor.localId | A04257 | - |
dc.contributor.localId | A03372 | - |
dc.relation.journalcode | J00457 | - |
dc.identifier.eissn | 1421-9751 | - |
dc.identifier.pmid | 17934270 | - |
dc.identifier.url | http://www.karger.com/Article/FullText/109407 | - |
dc.subject.keyword | Age Factors | - |
dc.subject.keyword | Aged | - |
dc.subject.keyword | Analysis of Variance | - |
dc.subject.keyword | Cardiomyopathy, Hypertrophic/diagnostic imaging* | - |
dc.subject.keyword | Cardiomyopathy, Hypertrophic/genetics* | - |
dc.subject.keyword | Cardiomyopathy, Hypertrophic/physiopathology | - |
dc.subject.keyword | Echocardiography, Doppler | - |
dc.subject.keyword | Electrocardiography | - |
dc.subject.keyword | Female | - |
dc.subject.keyword | Genetic Predisposition to Disease* | - |
dc.subject.keyword | Humans | - |
dc.subject.keyword | Linear Models | - |
dc.subject.keyword | Male | - |
dc.subject.keyword | Middle Aged | - |
dc.subject.keyword | Phenotype* | - |
dc.subject.keyword | Prognosis | - |
dc.subject.keyword | Prospective Studies | - |
dc.subject.keyword | Risk Assessment | - |
dc.subject.keyword | Severity of Illness Index | - |
dc.subject.keyword | Sex Factors | - |
dc.subject.keyword | Stroke Volume | - |
dc.contributor.alternativeName | Chung, Nam Sik | - |
dc.contributor.alternativeName | Choi, Eui Young | - |
dc.contributor.alternativeName | Ha, Jong Won | - |
dc.contributor.alternativeName | Rim, Se Joong | - |
dc.contributor.affiliatedAuthor | Chung, Nam Sik | - |
dc.contributor.affiliatedAuthor | Choi, Eui Young | - |
dc.contributor.affiliatedAuthor | Ha, Jong Won | - |
dc.contributor.affiliatedAuthor | Rim, Se Joong | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 110 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 53 | - |
dc.citation.endPage | 61 | - |
dc.identifier.bibliographicCitation | CARDIOLOGY, Vol.110(1) : 53-61, 2008 | - |
dc.identifier.rimsid | 54817 | - |
dc.type.rims | ART | - |
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