184 258

Cited 0 times in

돼지의 박동심장전위 모형에서 Norepinephrine 투여에 의한 혈역학적 지수들과 열확산 소식자(Thermal Diffusion Probe)로 측정한 국소심근관류의 변화

Other Titles
 Changes in hemodynamic parameters and regional myocardial perfusion measured by thermal diffusion probe from the infusion of norepinephrine during displacement of porcine beating heart 
Authors
 이종화  ;  방서욱  ;  박한기  ;  안지원  ;  곽영란  ;  홍용우 
Citation
 KOREAN JOURNAL OF ANESTHESIOLOGY, Vol.55(4) : 479-484, 2008 
Journal Title
 KOREAN JOURNAL OF ANESTHESIOLOGY 
ISSN
 2005-6419 
Issue Date
2008
Keywords
myocardial perfusion ; norepinephrine ; off-pump coronary artery bypass graft
Abstract
BACKGROUND: This study was done to evaluate the sole effect of norepinephrine on the regional myocardial perfusion during displacement of the porcine beating heart using thermal diffusion method. METHODS: Thermal diffusion probe was inserted into the anterior myocardial wall during 20 procedures in 10 male pigs (30-35 kg). The measurements of regional myocardial perfusion and hemodynamic parameters were performed after complete instrumentation (baseline), after displacement of the beating heart anteriorly, and 5 and 15 minutes after norepinephrine infusion, titrated to restore baseline mean arterial pressure (MAP). RESULTS: Norepinephrine infusion reversed the decrease in MAP and myocardial perfusion, caused by displacement of the beating heart (62 +/- 3% to 115 +/- 4% of baseline, P < 0.01; 41 +/- 5% to 125 +/- 4% of baseline, P < 0.05, respectively). CONCLUSIONS: Restoration of MAP with norepinephrine infusion without any preload augmentation reversed deterioration in regional myocardial perfusion during displacement of the porcine beating heart.
Files in This Item:
T200801347.pdf Download
DOI
10.4097/kjae.2008.55.4.479
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers
Yonsei Authors
Kwak, Young Lan(곽영란) ORCID logo https://orcid.org/0000-0002-2984-9927
Park, Han Ki(박한기) ORCID logo https://orcid.org/0000-0002-7472-7822
Bang, Sou Ouk(방서욱)
Lee, Jong Wha(이종화)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/107655
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse