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A Case of Rapidly Progressive Glomerulonephritis in a Hepatitis B Virus Carrier Successfully Treated with High dose Immunosuppressive Therapy and Prophylactic Lamivudine

 Jung Eun Lee  ;  Jung Myung Lee  ;  Beom Seok Kim  ;  Hyeun Joo Jeong  ;  Dae-Suk Han  ;  Ho Yung Lee  ;  Kyu Hun Choi  ;  Jung Tak Park 
 Korean Journal of Nephrology, Vol.27(5) : 622-625, 2008 
Journal Title
 Korean Journal of Nephrology 
Issue Date
A 35-year-old man, previously hepatitis B surface antigen (HBsAg) carrier, presented with gross hematuria and heavy proteinuria that he had been suffering from for 1 month. Serum creatinine was 4.4 mg/dL. Renal biopsy showed pauci-immune crescentic glomerulonephritis. He received plasmapheresis and was treated with high-dose steroids and cyclophosphamide. Lamivudine was started for the prevention of hepatitis B virus (HBV) activation. Serum creatinine and proteinuria were ameliorated one week after the treatment. There was no sign of HBV activation after six months of treatment. We report a case of rapidly progressive glomerulonephritis in a HBV carrier successfully treated with high dose immunosuppressive therapy and prophylactic lamivudine.
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실)
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실)
Yonsei Authors
김범석(Kim, Beom Seok) ; 박정탁(Park, Jung Tak) ; 이정명(Lee, Jung Myung) ; 이정은(Lee, Jung Eun) ; 이호영(Lee, Ho Yung) ; 정현주(Jeong, Hyeon Joo) ; 최규헌(Choi, Kyu Hun)
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