Cited 35 times in
Application of a peptide-based PF2D platform for quantitative proteomics in disease biomarker discovery
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김호근 | - |
dc.date.accessioned | 2015-05-19T17:07:55Z | - |
dc.date.available | 2015-05-19T17:07:55Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 1615-9853 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/107561 | - |
dc.description.abstract | A peptide-based 2-D liquid phase fractionation (PF2D) system was used in a quantitative proteomic analysis of hepatocellular carcinoma. 2-D liquid maps of peptide specimens showed better resolution than those of proteins, leading to the identification of differentially expressed proteins. Peptide-based PF2D gave well-matched theoretical and experimental pI values and was proven to be a very efficient and versatile analytical tool for both large-scale profiling and quantification of phosphoproteins in disease biomarker discovery. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 3371~3381 | - |
dc.relation.isPartOf | PROTEOMICS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Alkaline Phosphatase/metabolism | - |
dc.subject.MESH | Biomarkers/analysis* | - |
dc.subject.MESH | Biomarkers/blood | - |
dc.subject.MESH | Carcinoma, Hepatocellular/blood | - |
dc.subject.MESH | Carcinoma, Hepatocellular/diagnosis* | - |
dc.subject.MESH | Carcinoma, Hepatocellular/metabolism | - |
dc.subject.MESH | Chemical Fractionation/methods* | - |
dc.subject.MESH | Chromatography, Liquid | - |
dc.subject.MESH | Electrophoresis, Gel, Two-Dimensional | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Peptides/chemistry | - |
dc.subject.MESH | Peptides/metabolism* | - |
dc.subject.MESH | Proteomics/methods* | - |
dc.subject.MESH | Reproducibility of Results | - |
dc.subject.MESH | Tandem Mass Spectrometry | - |
dc.title | Application of a peptide-based PF2D platform for quantitative proteomics in disease biomarker discovery | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pathology (병리학) | - |
dc.contributor.googleauthor | Hyoung-Joo Lee | - |
dc.contributor.googleauthor | Min-Jeong Kang | - |
dc.contributor.googleauthor | Eun-Young Lee | - |
dc.contributor.googleauthor | Sang Yun Cho | - |
dc.contributor.googleauthor | Hoguen Kim | - |
dc.contributor.googleauthor | Young-Ki Paik | - |
dc.identifier.doi | 10.1002/pmic.200800111 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01183 | - |
dc.relation.journalcode | J02566 | - |
dc.identifier.eissn | 1615-9861 | - |
dc.identifier.pmid | 18651672 | - |
dc.identifier.url | http://onlinelibrary.wiley.com/doi/10.1002/pmic.200800111/abstract | - |
dc.subject.keyword | Biomarker | - |
dc.subject.keyword | HCC | - |
dc.subject.keyword | Peptide | - |
dc.subject.keyword | PF2D | - |
dc.subject.keyword | Quantitative proteomics | - |
dc.contributor.alternativeName | Kim, Ho Keun | - |
dc.contributor.affiliatedAuthor | Kim, Ho Keun | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 8 | - |
dc.citation.number | 16 | - |
dc.citation.startPage | 3371 | - |
dc.citation.endPage | 3381 | - |
dc.identifier.bibliographicCitation | PROTEOMICS, Vol.8(16) : 3371-3381, 2008 | - |
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