Cited 0 times in
Clinical Significance of Margin Status in Postoperative Radiotherapy for Extremity and Truncal Soft-Tissue Sarcoma
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 신규호 | - |
dc.contributor.author | 한수봉 | - |
dc.contributor.author | 김귀언 | - |
dc.contributor.author | 김용배 | - |
dc.contributor.author | 노재경 | - |
dc.contributor.author | 서창옥 | - |
dc.contributor.author | 성진실 | - |
dc.date.accessioned | 2015-05-19T17:05:31Z | - |
dc.date.available | 2015-05-19T17:05:31Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 0360-3016 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/107491 | - |
dc.description.abstract | PURPOSE: To evaluate whether adjuvant radiotherapy (RT) in extremity and truncal soft-tissue sarcoma (STS) patients with microscopically positive or close margins after excision can achieve comparable local control to that of excision with negative margin plus RT. METHODS AND MATERIALS: A total of 150 patients (111 extremity and 39 trunk cases) treated with conserving surgery and adjuvant RT was analyzed. All surgical margins were classified as being a negative margin or a positive or close margin based on pathologic margin width. RT was delivered with a shrinking-field technique in 150 patients (median, 63 Gy). RESULTS: All patients were divided into two groups: (A) excision with negative margins plus RT (n = 56) and (B) excision with positive or close margins plus RT (n = 94). Overall, the 5-year local failure-free survival in all patients was 72.9%, and no significant differences were found between the two groups (Group A, 74.7%; Group B, 71.6%). High tumor grade was found to be a significant predictor of local failure. However, Group A was superior to Group B in distant metastasis-free survival (p = 0.02). No significant differences were shown in overall survival between the two groups. CONCLUSIONS: In our series, margin status did not predict for LF when adjuvant RT was used. We believe that when adjuvant RT is used, re-resection may not be necessary for selected patients with positive or close pathologic margins in the management of extremity and truncal STS patients. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 139~144 | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Child | - |
dc.subject.MESH | Disease-Free Survival | - |
dc.subject.MESH | Extremities | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoplasm, Residual | - |
dc.subject.MESH | Radiotherapy Dosage | - |
dc.subject.MESH | Radiotherapy, Adjuvant/adverse effects | - |
dc.subject.MESH | Regression Analysis | - |
dc.subject.MESH | Sarcoma/mortality | - |
dc.subject.MESH | Sarcoma/pathology* | - |
dc.subject.MESH | Sarcoma/radiotherapy* | - |
dc.subject.MESH | Sarcoma/surgery | - |
dc.subject.MESH | Soft Tissue Neoplasms/mortality | - |
dc.subject.MESH | Soft Tissue Neoplasms/pathology* | - |
dc.subject.MESH | Soft Tissue Neoplasms/radiotherapy* | - |
dc.subject.MESH | Soft Tissue Neoplasms/surgery | - |
dc.subject.MESH | Treatment Failure | - |
dc.title | Clinical Significance of Margin Status in Postoperative Radiotherapy for Extremity and Truncal Soft-Tissue Sarcoma | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | YONG BAE KIM | - |
dc.contributor.googleauthor | KYU HO SHIN | - |
dc.contributor.googleauthor | JINSIL SEONG | - |
dc.contributor.googleauthor | JAE KYUNG ROH | - |
dc.contributor.googleauthor | GWI EON KIM | - |
dc.contributor.googleauthor | SOO BONG HAHN | - |
dc.contributor.googleauthor | CHANG OK SUH | - |
dc.identifier.doi | 17919843 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02086 | - |
dc.contributor.localId | A04293 | - |
dc.contributor.localId | A00321 | - |
dc.contributor.localId | A01290 | - |
dc.contributor.localId | A01919 | - |
dc.contributor.localId | A01956 | - |
dc.contributor.localId | A00744 | - |
dc.relation.journalcode | J01157 | - |
dc.identifier.eissn | 1879-355X | - |
dc.identifier.pmid | 17919843 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0360301607010255 | - |
dc.subject.keyword | Adolescent | - |
dc.subject.keyword | Adult | - |
dc.subject.keyword | Aged | - |
dc.subject.keyword | Aged, 80 and over | - |
dc.subject.keyword | Child | - |
dc.subject.keyword | Disease-Free Survival | - |
dc.subject.keyword | Extremities | - |
dc.subject.keyword | Female | - |
dc.subject.keyword | Humans | - |
dc.subject.keyword | Male | - |
dc.subject.keyword | Middle Aged | - |
dc.subject.keyword | Neoplasm, Residual | - |
dc.subject.keyword | Radiotherapy Dosage | - |
dc.subject.keyword | Radiotherapy, Adjuvant/adverse effects | - |
dc.subject.keyword | Regression Analysis | - |
dc.subject.keyword | Sarcoma/mortality | - |
dc.subject.keyword | Sarcoma/pathology* | - |
dc.subject.keyword | Sarcoma/radiotherapy* | - |
dc.subject.keyword | Sarcoma/surgery | - |
dc.subject.keyword | Soft Tissue Neoplasms/mortality | - |
dc.subject.keyword | Soft Tissue Neoplasms/pathology* | - |
dc.subject.keyword | Soft Tissue Neoplasms/radiotherapy* | - |
dc.subject.keyword | Soft Tissue Neoplasms/surgery | - |
dc.subject.keyword | Treatment Failure | - |
dc.contributor.alternativeName | Shin, Kyoo Ho | - |
dc.contributor.alternativeName | Hahn, Soo Bong | - |
dc.contributor.alternativeName | Kim, Gwi Eon | - |
dc.contributor.alternativeName | Kim, Yong Bae | - |
dc.contributor.alternativeName | Roh, Jae Kyung | - |
dc.contributor.alternativeName | Suh, Chang Ok | - |
dc.contributor.alternativeName | Seong, Jin Sil | - |
dc.contributor.affiliatedAuthor | Shin, Kyoo Ho | - |
dc.contributor.affiliatedAuthor | Hahn, Soo Bong | - |
dc.contributor.affiliatedAuthor | Kim, Gwi Eon | - |
dc.contributor.affiliatedAuthor | Roh, Jae Kyung | - |
dc.contributor.affiliatedAuthor | Suh, Chang Ok | - |
dc.contributor.affiliatedAuthor | Seong, Jin Sil | - |
dc.contributor.affiliatedAuthor | Kim, Yong Bae | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 70 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 139 | - |
dc.citation.endPage | 144 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, Vol.70(1) : 139-144, 2008 | - |
dc.identifier.rimsid | 56902 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.