Cited 31 times in
Effects of target concentration infusion of propofol and tracheal intubation on QTc interval
DC Field | Value | Language |
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dc.contributor.author | 권태동 | - |
dc.contributor.author | 남상범 | - |
dc.contributor.author | 이종석 | - |
dc.contributor.author | 한동우 | - |
dc.date.accessioned | 2015-05-19T16:52:19Z | - |
dc.date.available | 2015-05-19T16:52:19Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 0003-2409 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/107097 | - |
dc.description.abstract | This study was designed to evaluate the effect of target controlled infusion of propofol on QTc interval and tracheal intubation. Twenty-five unpremedicated, ASA class I or II patients were selected and target concentration infusion of propofol at 5 microg x ml(-1) was used throughout the study. The QTc interval was measured before anaesthetic induction (baseline, T1), 10 min after propofol infusion (T2), immediately after tracheal intubation (T3), and 1 min after tracheal intubation (T4). The QTc interval increased significantly at 10 min after the propofol infusion started compared to baseline (p = 0.003). After tracheal intubation, the QTc interval was further increased when compared to that at T2 (p < 0.0001). The increased QTc interval was within normal limit and no patient had an arrhythmia. In conclusion, although statistically significant, the increase in QTc interval was too small to be clinically significant during propofol infusion. However, the combination of propofol and tracheal intubation must be used carefully in patients with prolonged QTc interval. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1061~1064 | - |
dc.relation.isPartOf | ANAESTHESIA | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Anesthetics, Intravenous/administration & dosage | - |
dc.subject.MESH | Anesthetics, Intravenous/adverse effects* | - |
dc.subject.MESH | Blood Pressure/drug effects | - |
dc.subject.MESH | Heart Rate/drug effects | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Infusions, Intravenous | - |
dc.subject.MESH | Intubation, Intratracheal/adverse effects* | - |
dc.subject.MESH | Long QT Syndrome/chemically induced | - |
dc.subject.MESH | Long QT Syndrome/etiology* | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Monitoring, Intraoperative/methods | - |
dc.subject.MESH | Propofol/administration & dosage | - |
dc.subject.MESH | Propofol/adverse effects* | - |
dc.title | Effects of target concentration infusion of propofol and tracheal intubation on QTc interval | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Anesthesiology (마취통증의학) | - |
dc.contributor.googleauthor | D. H. Kim | - |
dc.contributor.googleauthor | T. D. Kweon | - |
dc.contributor.googleauthor | S. B. Nam | - |
dc.contributor.googleauthor | D. W. Han | - |
dc.contributor.googleauthor | W. Y. Cho | - |
dc.contributor.googleauthor | J. S. Lee | - |
dc.identifier.doi | 10.1111/j.1365-2044.2008.05564.x | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00255 | - |
dc.contributor.localId | A01253 | - |
dc.contributor.localId | A04274 | - |
dc.contributor.localId | A03141 | - |
dc.contributor.localId | A00390 | - |
dc.relation.journalcode | J00128 | - |
dc.identifier.eissn | 1365-2044 | - |
dc.identifier.pmid | 18717665 | - |
dc.identifier.url | http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2044.2008.05564.x/abstract | - |
dc.subject.keyword | Adult | - |
dc.subject.keyword | Anesthetics, Intravenous/administration & dosage | - |
dc.subject.keyword | Anesthetics, Intravenous/adverse effects* | - |
dc.subject.keyword | Blood Pressure/drug effects | - |
dc.subject.keyword | Heart Rate/drug effects | - |
dc.subject.keyword | Humans | - |
dc.subject.keyword | Infusions, Intravenous | - |
dc.subject.keyword | Intubation, Intratracheal/adverse effects* | - |
dc.subject.keyword | Long QT Syndrome/chemically induced | - |
dc.subject.keyword | Long QT Syndrome/etiology* | - |
dc.subject.keyword | Middle Aged | - |
dc.subject.keyword | Monitoring, Intraoperative/methods | - |
dc.subject.keyword | Propofol/administration & dosage | - |
dc.subject.keyword | Propofol/adverse effects* | - |
dc.contributor.alternativeName | Kweon, Tae Dong | - |
dc.contributor.alternativeName | Nam, Sang Beom | - |
dc.contributor.alternativeName | Lee, Jong Seok | - |
dc.contributor.alternativeName | Han, Dong Woo | - |
dc.contributor.affiliatedAuthor | Kweon, Tae Dong | - |
dc.contributor.affiliatedAuthor | Nam, Sang Beom | - |
dc.contributor.affiliatedAuthor | Han, Dong Woo | - |
dc.contributor.affiliatedAuthor | Lee, Jong Seok | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 63 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 1061 | - |
dc.citation.endPage | 1064 | - |
dc.identifier.bibliographicCitation | ANAESTHESIA, Vol.63(10) : 1061-1064, 2008 | - |
dc.identifier.rimsid | 49530 | - |
dc.type.rims | ART | - |
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