Cited 18 times in
Clinical characteristics and outcome for hepatitis C virus-positive diffuse large B-cell lymphoma
DC Field | Value | Language |
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dc.contributor.author | 김진석 | - |
dc.date.accessioned | 2015-05-19T16:50:47Z | - |
dc.date.available | 2015-05-19T16:50:47Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 1042-8194 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/107051 | - |
dc.description.abstract | Several previous studies have addressed the association between hepatitis C virus (HCV) infection and non-Hodgkin lymphoma (NHL), but there are few studies on HCV-related diffuse large B-cell lymphoma (DLBL). We conducted this retrospective study to investigate the distinctive clinical characteristics and outcome for HCV-positive DLBL. We compared the clinical characteristics and outcomes of 32 HCV-positive DLBL cases from nine Korean institutions with those of 371 HCV-negative DLBL cases. A higher percentage of HCV-positive DLBL cases were associated with old age (> or = 60) than HCV-negative DLBL cases at diagnosis (59.4% vs. 36.1%, respectively, P = 0.009) and HCV-positive cases were less likely than HCV-negative cases to have extranodal involvement (53.1% vs. 71.1%, respectively, P = 0.044). The nodal presentation was the only independent factor favorably influencing the event free survival (EFS) in HCV-positive DLBL (HR = 0.11, 95% CI; 0.01-0.95, P = 0.012). In comparison to patients with HCV-negative DLBL, HCV-positive DLBL patients had a superior complete response rate (P = 0.023) and EFS (P = 0.02). In Korean patients, HCV-positive DLBL is more common with old age and has less extranodal involvement than does HCV-negative DLBL. The superior survival outcome for HCV-positive DLBL should be verified by further investigation, especially with respect to its correlation with transformed low-grade NHL | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 88~94 | - |
dc.relation.isPartOf | LEUKEMIA & LYMPHOMA | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Age Factors | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Hepacivirus* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Korea | - |
dc.subject.MESH | Lymphoma, Large B-Cell, Diffuse/epidemiology | - |
dc.subject.MESH | Lymphoma, Large B-Cell, Diffuse/mortality | - |
dc.subject.MESH | Lymphoma, Large B-Cell, Diffuse/virology* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Remission Induction | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Survival Analysis | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Clinical characteristics and outcome for hepatitis C virus-positive diffuse large B-cell lymphoma | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | BYEONG-BAE PARK | - |
dc.contributor.googleauthor | JIN SEOK KIM | - |
dc.contributor.googleauthor | YOUNG-YUEL LEE | - |
dc.contributor.googleauthor | HYE JIN KANG | - |
dc.contributor.googleauthor | BAEK YEOL RYOO | - |
dc.contributor.googleauthor | JUNG HUN KANG | - |
dc.contributor.googleauthor | HO YOUNG KIM | - |
dc.contributor.googleauthor | BONG-SEOG KIM | - |
dc.contributor.googleauthor | SUNG YONG OH | - |
dc.contributor.googleauthor | HYUK CHAN KWON | - |
dc.contributor.googleauthor | JONG HO WON | - |
dc.contributor.googleauthor | KIHYUN KIM | - |
dc.contributor.googleauthor | KEUNCHIL PARK | - |
dc.contributor.googleauthor | CHEOLWON SUH | - |
dc.contributor.googleauthor | WON SEOG KIM | - |
dc.identifier.doi | 10.1080/10428190701732861 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01017 | - |
dc.relation.journalcode | J02165 | - |
dc.identifier.eissn | 1029-2403 | - |
dc.identifier.pmid | 18203017 | - |
dc.identifier.url | http://informahealthcare.com/doi/abs/10.1080/10428190701732861 | - |
dc.subject.keyword | Hepatitis C virus | - |
dc.subject.keyword | diffuse large B-cell lymphoma | - |
dc.subject.keyword | clinical outcome | - |
dc.contributor.alternativeName | Kim, Jin Seok | - |
dc.contributor.affiliatedAuthor | Kim, Jin Seok | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 49 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 88 | - |
dc.citation.endPage | 94 | - |
dc.identifier.bibliographicCitation | LEUKEMIA & LYMPHOMA, Vol.49(1) : 88-94, 2008 | - |
dc.identifier.rimsid | 49493 | - |
dc.type.rims | ART | - |
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