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Plasma free fatty acid level patterns according to cardiovascular risk status in postmenopausal women
DC Field | Value | Language |
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dc.contributor.author | 강은석 | - |
dc.contributor.author | 고영국 | - |
dc.contributor.author | 이유미 | - |
dc.contributor.author | 이현철 | - |
dc.contributor.author | 임승길 | - |
dc.contributor.author | 차봉수 | - |
dc.date.accessioned | 2015-05-19T16:47:28Z | - |
dc.date.available | 2015-05-19T16:47:28Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 0009-8981 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/106951 | - |
dc.description.abstract | BACKGROUND: The present study examines changes in the pattern of plasma free polyunsaturated fatty acids (PUFA) according to menopausal status and the existence of diabetes mellitus (DM) or coronary heart disease (CHD) in Korean women. METHODS: The participants were as follows; premenopausal women (PRE, n=20) and postmenopausal women without any known chronic disease (POST, n=35), with DM (DM, n=35), or with angiographically proven CHD (CHD, n=30). Plasma free fatty acids were measured in all participants. RESULTS: Healthy premenopausal women had a higher ratio of omega-3/omega-6 PUFA than postmenopausal women (p=0.001). As expected, the PRE group had higher docsapentaenoic acid (DPA) and docosahexaenoic acid (DHA) levels (p<0.05) and lower arachidonic acid levels (p<0.05) than the POST group. In turn, the healthy POST group had higher levels of DPA and DHA compared to the DM or CHD groups (p<0.05). There were significant shifts of increased omega-6 and decreased omega-3 among the women, according to each disease. CONCLUSIONS: There was a significant relationship between omega-3 and omega-6 PUFA profiles and risk for CHD in women. This metabolic profile of PUFA might be an important surrogate marker in postmenopausal women. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 11~16 | - |
dc.relation.isPartOf | CLINICA CHIMICA ACTA | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Body Mass Index | - |
dc.subject.MESH | Coronary Disease/etiology* | - |
dc.subject.MESH | Fatty Acids, Nonesterified/blood* | - |
dc.subject.MESH | Fatty Acids, Unsaturated/blood* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Korea | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Organic Chemicals | - |
dc.subject.MESH | Postmenopause/blood* | - |
dc.subject.MESH | Risk Factors | - |
dc.title | Plasma free fatty acid level patterns according to cardiovascular risk status in postmenopausal women | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Yumie Rhee | - |
dc.contributor.googleauthor | Man-Jeong Paik | - |
dc.contributor.googleauthor | Kyoung-Rae Kim | - |
dc.contributor.googleauthor | Young-Guk Ko | - |
dc.contributor.googleauthor | Eun Seok Kang | - |
dc.contributor.googleauthor | Bong Soo Cha | - |
dc.contributor.googleauthor | Hyun Chul Lee | - |
dc.contributor.googleauthor | Sung-Kil Lim | - |
dc.identifier.doi | 10.1016/j.cca.2008.02.012 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00068 | - |
dc.contributor.localId | A00127 | - |
dc.contributor.localId | A03012 | - |
dc.contributor.localId | A03301 | - |
dc.contributor.localId | A03375 | - |
dc.contributor.localId | A03996 | - |
dc.relation.journalcode | J00543 | - |
dc.identifier.eissn | 1873-3492 | - |
dc.identifier.pmid | 18328818 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0009898108000776 | - |
dc.subject.keyword | Polyunsaturated fatty acid | - |
dc.subject.keyword | Menopause | - |
dc.subject.keyword | Diabetes mellitus | - |
dc.subject.keyword | Coronary heart disease | - |
dc.contributor.alternativeName | Kang, Eun Seok | - |
dc.contributor.alternativeName | Ko, Young Guk | - |
dc.contributor.alternativeName | Rhee, Yumie | - |
dc.contributor.alternativeName | Lee, Hyun Chul | - |
dc.contributor.alternativeName | Lim, Sung Kil | - |
dc.contributor.alternativeName | Cha, Bong Soo | - |
dc.contributor.affiliatedAuthor | Kang, Eun Seok | - |
dc.contributor.affiliatedAuthor | Ko, Young Guk | - |
dc.contributor.affiliatedAuthor | Rhee, Yumie | - |
dc.contributor.affiliatedAuthor | Lee, Hyun Chul | - |
dc.contributor.affiliatedAuthor | Lim, Sung Kil | - |
dc.contributor.affiliatedAuthor | Cha, Bong Soo | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 392 | - |
dc.citation.number | 1-2 | - |
dc.citation.startPage | 11 | - |
dc.citation.endPage | 16 | - |
dc.identifier.bibliographicCitation | CLINICA CHIMICA ACTA, Vol.392(1-2) : 11-16, 2008 | - |
dc.identifier.rimsid | 56392 | - |
dc.type.rims | ART | - |
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