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Effect of geometric remodeling on left ventricular longitudinal contractile reserve in patients with hypertension

DC FieldValueLanguage
dc.contributor.author임세중-
dc.contributor.author정남식-
dc.contributor.author최동훈-
dc.contributor.author최의영-
dc.contributor.author고영국-
dc.contributor.author하종원-
dc.contributor.author박성하-
dc.contributor.author서혜선-
dc.contributor.author심지영-
dc.date.accessioned2015-05-19T16:44:08Z-
dc.date.available2015-05-19T16:44:08Z-
dc.date.issued2008-
dc.identifier.issn0894-7317-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/106847-
dc.description.abstractLeft ventricular hypertrophy (LVH) is associated with a reduction of subendocardial coronary flow reserve, which may be associated with abnormal myocardial longitudinal function during exercise. To test this hypothesis, 182 hypertensive patients underwent multistage supine bicycle exercise testing. Patients were classified as follows: patients with normal geometry (group 1, n = 116), concentric remodeling (group 2, n = 31), or LVH (group 3, n = 31). The results showed that the ratio of E/E', an index of left ventricular (LV) filling pressure, was significantly elevated in the LVH group at rest and during exercise. At rest, the mitral annular systolic velocity (S') was similar between the three groups at rest, whereas S' during exercise was significantly lower in the LVH group. The magnitude of change in S' during exercise was also significantly lower in the LVH group. Multiple linear regression analysis showed that peak double product (beta = 0.208, P = .006) and LV mass index (beta = -0.158, P = .028) were independently associated with LV longitudinal contractile reserve. Also, multiple linear regression analysis showed that changes in S' from baseline to peak were independently associated with exercise duration (beta = 0.123, P = .041) when controlled for age, male gender, baseline E', peak systolic blood pressure, and LV mass index. The results from this study demonstrate that LVH was significantly associated with abnormal LV longitudinal contractile reserve in hypertensive patients.-
dc.description.statementOfResponsibilityopen-
dc.format.extent246~250-
dc.relation.isPartOfJOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHCoronary Circulation-
dc.subject.MESHExercise Test-
dc.subject.MESHFemale-
dc.subject.MESHFractional Flow Reserve, Myocardial*-
dc.subject.MESHHumans-
dc.subject.MESHHypertension/complications*-
dc.subject.MESHHypertension/diagnostic imaging*-
dc.subject.MESHHypertrophy, Left Ventricular/diagnostic imaging*-
dc.subject.MESHHypertrophy, Left Ventricular/etiology*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHReproducibility of Results-
dc.subject.MESHSensitivity and Specificity-
dc.subject.MESHUltrasonography-
dc.subject.MESHVentricular Dysfunction, Left/diagnostic imaging*-
dc.subject.MESHVentricular Dysfunction, Left/etiology*-
dc.subject.MESHVentricular Remodeling-
dc.titleEffect of geometric remodeling on left ventricular longitudinal contractile reserve in patients with hypertension-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorSungha Park-
dc.contributor.googleauthorHye-Sun Seo-
dc.contributor.googleauthorChi Young Shim-
dc.contributor.googleauthorEui Young Choi-
dc.contributor.googleauthorYoung-Guk Ko-
dc.contributor.googleauthorDonghoon Choi-
dc.contributor.googleauthorJong-Won Ha-
dc.contributor.googleauthorSe-Joong Rim-
dc.contributor.googleauthorNamsik Chung-
dc.identifier.doi10.1016/j.echo.2007.06.005-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA03372-
dc.contributor.localIdA03585-
dc.contributor.localIdA04053-
dc.contributor.localIdA04165-
dc.contributor.localIdA00127-
dc.contributor.localIdA04257-
dc.contributor.localIdA01512-
dc.contributor.localIdA01923-
dc.contributor.localIdA02213-
dc.relation.journalcodeJ01777-
dc.identifier.eissn1097-6795-
dc.identifier.pmid17658727-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0894731707004774-
dc.subject.keywordCoronary Circulation-
dc.subject.keywordExercise Test-
dc.subject.keywordFemale-
dc.subject.keywordFractional Flow Reserve, Myocardial*-
dc.subject.keywordHumans-
dc.subject.keywordHypertension/complications*-
dc.subject.keywordHypertension/diagnostic imaging*-
dc.subject.keywordHypertrophy, Left Ventricular/diagnostic imaging*-
dc.subject.keywordHypertrophy, Left Ventricular/etiology*-
dc.subject.keywordMale-
dc.subject.keywordMiddle Aged-
dc.subject.keywordReproducibility of Results-
dc.subject.keywordSensitivity and Specificity-
dc.subject.keywordUltrasonography-
dc.subject.keywordVentricular Dysfunction, Left/diagnostic imaging*-
dc.subject.keywordVentricular Dysfunction, Left/etiology*-
dc.subject.keywordVentricular Remodeling-
dc.contributor.alternativeNameRim, Se Joong-
dc.contributor.alternativeNameChung, Nam Sik-
dc.contributor.alternativeNameChoi, Dong Hoon-
dc.contributor.alternativeNameChoi, Eui Young-
dc.contributor.alternativeNameKo, Young Guk-
dc.contributor.alternativeNameHa, Jong Won-
dc.contributor.alternativeNamePark, Sung Ha-
dc.contributor.alternativeNameSeo, Hye Sun-
dc.contributor.alternativeNameShim, Chi Young-
dc.contributor.affiliatedAuthorRim, Se Joong-
dc.contributor.affiliatedAuthorChung, Nam Sik-
dc.contributor.affiliatedAuthorChoi, Dong Hoon-
dc.contributor.affiliatedAuthorChoi, Eui Young-
dc.contributor.affiliatedAuthorKo, Young Guk-
dc.contributor.affiliatedAuthorHa, Jong Won-
dc.contributor.affiliatedAuthorPark, Sung Ha-
dc.contributor.affiliatedAuthorSeo, Hye Sun-
dc.contributor.affiliatedAuthorShim, Chi Young-
dc.rights.accessRightsnot free-
dc.citation.volume21-
dc.citation.number3-
dc.citation.startPage246-
dc.citation.endPage250-
dc.identifier.bibliographicCitationJOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY, Vol.21(3) : 246-250, 2008-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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