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Effects of increasing particle size of low-density lipoprotein on restenosis after coronary stent implantation
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 권혁문 | - |
dc.contributor.author | 김정호 | - |
dc.contributor.author | 김중선 | - |
dc.contributor.author | 김창수 | - |
dc.contributor.author | 민필기 | - |
dc.contributor.author | 윤세정 | - |
dc.contributor.author | 윤영원 | - |
dc.contributor.author | 이병권 | - |
dc.contributor.author | 이지혁 | - |
dc.contributor.author | 임세중 | - |
dc.contributor.author | 홍범기 | - |
dc.date.accessioned | 2015-05-19T16:42:25Z | - |
dc.date.available | 2015-05-19T16:42:25Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 1346-9843 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/106793 | - |
dc.description.abstract | BACKGROUND: Small dense low-density lipoprotein (LDL) has emerged as an important risk factor in coronary atherosclerosis and vascular inflammation, which is related to neointimal hyperplasia. Therefore, the aim of the present study was to investigate whether changes in LDL particle size are related to in-stent restenosis (ISR). METHODS AND RESULTS: The LDL subfraction and lipid profiles were measured in 274 patients (412 stents) at both baseline and follow-up coronary angiography (CAG). The incidence of ISR (80 lesions, 19.4%) was lower in the patients with increased LDL particle size than in those with no change or decrease (14.2% vs 25.8%, p=0.004). Logistic multivariate analysis revealed that stent length (>or=24 mm) (odds ratio (OR) =1.913, p=0.027), post minimal luminal diameter (>3 mm) (OR =0.528, p=0.028), acute coronary syndrome (OR =2.294, p=0.005), decrease in high-density lipoprotein-cholesterol (OR =1.028, p=0.047) and increase in LDL particle size (OR =0.528, p=0.031) were independent predictors for ISR. CONCLUSIONS: In the present study, an increase in the LDL particle size between baseline and follow-up CAG was associated with reduced incidence of ISR. Therefore, modification of LDL particle size may have a beneficial effect on the risk of ISR | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1059~1064 | - |
dc.relation.isPartOf | CIRCULATION JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Acute Coronary Syndrome/diagnostic imaging | - |
dc.subject.MESH | Acute Coronary Syndrome/epidemiology | - |
dc.subject.MESH | Acute Coronary Syndrome/metabolism | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Angioplasty, Balloon, Coronary* | - |
dc.subject.MESH | Coronary Angiography | - |
dc.subject.MESH | Coronary Restenosis/diagnostic imaging | - |
dc.subject.MESH | Coronary Restenosis/epidemiology* | - |
dc.subject.MESH | Coronary Restenosis/metabolism* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Incidence | - |
dc.subject.MESH | Lipoproteins, LDL/blood* | - |
dc.subject.MESH | Lipoproteins, LDL/chemistry | - |
dc.subject.MESH | Logistic Models | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Multivariate Analysis | - |
dc.subject.MESH | Particle Size | - |
dc.subject.MESH | Predictive Value of Tests | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Stents* | - |
dc.title | Effects of increasing particle size of low-density lipoprotein on restenosis after coronary stent implantation | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학) | - |
dc.contributor.googleauthor | Jung-Sun Kim | - |
dc.contributor.googleauthor | Myung-Hyun Kim | - |
dc.contributor.googleauthor | Byoung Kwon Lee | - |
dc.contributor.googleauthor | Se-Joong Rim | - |
dc.contributor.googleauthor | Pil-Ki Min | - |
dc.contributor.googleauthor | Se-Jung Yoon | - |
dc.contributor.googleauthor | Jeong-Ho Kim | - |
dc.contributor.googleauthor | Ji-Hyuck Rhee | - |
dc.contributor.googleauthor | Young Won Yoon | - |
dc.contributor.googleauthor | Bum Kee Hong | - |
dc.contributor.googleauthor | Hyuck Moon Kwon | - |
dc.contributor.googleauthor | Changsoo Kim | - |
dc.identifier.doi | 18577812 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00260 | - |
dc.contributor.localId | A00903 | - |
dc.contributor.localId | A00961 | - |
dc.contributor.localId | A01042 | - |
dc.contributor.localId | A01412 | - |
dc.contributor.localId | A02569 | - |
dc.contributor.localId | A02580 | - |
dc.contributor.localId | A02793 | - |
dc.contributor.localId | A03213 | - |
dc.contributor.localId | A03372 | - |
dc.contributor.localId | A04394 | - |
dc.relation.journalcode | J00534 | - |
dc.identifier.eissn | 1347-4820 | - |
dc.identifier.pmid | 18577812 | - |
dc.subject.keyword | Coronary stent | - |
dc.subject.keyword | Restenosis | - |
dc.subject.keyword | Small dense low-density lipoprotein | - |
dc.contributor.alternativeName | Kwon, Hyuck Moon | - |
dc.contributor.alternativeName | Kim, Jeong Ho | - |
dc.contributor.alternativeName | Kim, Jung Sun | - |
dc.contributor.alternativeName | Kim, Chang Soo | - |
dc.contributor.alternativeName | Min, Pil Ki | - |
dc.contributor.alternativeName | Yoon, Se Jung | - |
dc.contributor.alternativeName | Yoon, Young Won | - |
dc.contributor.alternativeName | Lee, Byoung Kwon | - |
dc.contributor.alternativeName | Rhee, Ji Hyuk | - |
dc.contributor.alternativeName | Rim, Se Joong | - |
dc.contributor.alternativeName | Hong, Bum Kee | - |
dc.contributor.affiliatedAuthor | Kwon, Hyuck Moon | - |
dc.contributor.affiliatedAuthor | Kim, Jeong Ho | - |
dc.contributor.affiliatedAuthor | Kim, Jung Sun | - |
dc.contributor.affiliatedAuthor | Kim, Chang Soo | - |
dc.contributor.affiliatedAuthor | Min, Pil Ki | - |
dc.contributor.affiliatedAuthor | Yoon, Se Jung | - |
dc.contributor.affiliatedAuthor | Yoon, Young Won | - |
dc.contributor.affiliatedAuthor | Lee, Byoung Kwon | - |
dc.contributor.affiliatedAuthor | Rhee, Ji Hyuk | - |
dc.contributor.affiliatedAuthor | Rim, Se Joong | - |
dc.contributor.affiliatedAuthor | Hong, Bum Kee | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 72 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 1059 | - |
dc.citation.endPage | 1064 | - |
dc.identifier.bibliographicCitation | CIRCULATION JOURNAL, Vol.72(7) : 1059-1064, 2008 | - |
dc.identifier.rimsid | 50855 | - |
dc.type.rims | ART | - |
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