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토끼 심내막염 모델에서 Glycopeptide Intermediate Staphylococcus aureus에 대한 Arbekacin과 Teicoplanin 병용 요법의 효과

DC FieldValueLanguage
dc.contributor.author한상훈-
dc.contributor.author김명수-
dc.contributor.author김준명-
dc.contributor.author김창기-
dc.contributor.author김창오-
dc.contributor.author송영구-
dc.contributor.author용동은-
dc.contributor.author이경원-
dc.contributor.author이한성-
dc.contributor.author정수진-
dc.contributor.author조정호-
dc.contributor.author진범식-
dc.contributor.author최석훈-
dc.contributor.author최준용-
dc.contributor.author최희경-
dc.date.accessioned2015-05-19T16:42:17Z-
dc.date.available2015-05-19T16:42:17Z-
dc.date.issued2008-
dc.identifier.issn1598-8112-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/106789-
dc.description.abstractBACKGROUND: There have been no reports to evaluate the usefulness of combination therapy with glycopeptide and arbekacin in endocarditis by in vivo model. MATERIALS AND METHODS: We investigated the efficacy of the arbekacin and teicoplanin combination on glycopeptide intermediate Staphylococcus aureus (GISA) in rabbit model of endocardits. GISA Mu50 strain was used for the experiment. The rabbit model of aortic valve endocarditis as described previously was used. Treatment was started 20h later inoculation with teicoplanin alone (at 20 mg/kg of body weight intramuscularly every 12 hours for 4 days after loading dose of 40 mg/kg of body weight intramuscularly), arbekacin alone (5 mg/kg of body weight intramuscularly every 12h for 4 days), or teicoplanin plus arbekacin. The results of therapy for experimental endocarditis due to Mu50 showed that teicoplanin and arbekacin combination was more effective than the administration of both drugs alone in reducing the log10CFU/g of aortic vegetation (P<0.05). CONCLUSION: The combination of teicoplanin and arbekacin was more effective against GISA (Mu50) than both drugs alone in vivo endocarditis model.-
dc.description.statementOfResponsibilityopen-
dc.format.extent102~106-
dc.relation.isPartOfInfection and Chemotherapy (감염과 화학요법)-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.title토끼 심내막염 모델에서 Glycopeptide Intermediate Staphylococcus aureus에 대한 Arbekacin과 Teicoplanin 병용 요법의 효과-
dc.title.alternativeEfficacy of the Arbekacin and Teicoplanin Combination on Glycopeptide Intermediate Staphylococcus aureus in a Rabbit Model of Endocarditis-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Laboratory Medicine (진단검사의학)-
dc.contributor.googleauthorCheong Ho Cho-
dc.contributor.googleauthorJun Yong Choi-
dc.contributor.googleauthorSang Hoon Han-
dc.contributor.googleauthorHan Sung Lee-
dc.contributor.googleauthorSuk Hoon Choi-
dc.contributor.googleauthorBum Sik Chin-
dc.contributor.googleauthorHee Kyoung Choi-
dc.contributor.googleauthorSu Jin Jeoung-
dc.contributor.googleauthorMyung Soo Kim-
dc.contributor.googleauthorChang Oh Kim-
dc.contributor.googleauthorChang Ki Kim-
dc.contributor.googleauthorDongeun Yong-
dc.contributor.googleauthorYoung Goo Song-
dc.contributor.googleauthorKyungwon Lee-
dc.contributor.googleauthorJune Myung Kim-
dc.identifier.doi10.3947/ic.2008.40.2.102-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA04286-
dc.contributor.localIdA00953-
dc.contributor.localIdA01038-
dc.contributor.localIdA01044-
dc.contributor.localIdA02037-
dc.contributor.localIdA02423-
dc.contributor.localIdA02649-
dc.contributor.localIdA03277-
dc.contributor.localIdA03638-
dc.contributor.localIdA03905-
dc.contributor.localIdA03981-
dc.contributor.localIdA04071-
dc.contributor.localIdA04191-
dc.contributor.localIdA04228-
dc.contributor.localIdA00423-
dc.relation.journalcodeJ01054-
dc.identifier.pmidEndocarditis, Staphylococcus aureus;Teicoplanin ; Arbekacin-
dc.subject.keywordEndocarditis, Staphylococcus aureus-
dc.subject.keywordTeicoplanin-
dc.subject.keywordArbekacin-
dc.contributor.alternativeNameHan, Sang Hoon-
dc.contributor.alternativeNameKim, Myoung Soo-
dc.contributor.alternativeNameKim, June Myung-
dc.contributor.alternativeNameKim, Chang Ki-
dc.contributor.alternativeNameKim, Chang Oh-
dc.contributor.alternativeNameSong, Young Goo-
dc.contributor.alternativeNameYong, Dong Eun-
dc.contributor.alternativeNameLee, Kyung Won-
dc.contributor.alternativeNameLee, Han Sung-
dc.contributor.alternativeNameJeong, Su Jin-
dc.contributor.alternativeNameCho, Cheong Ho-
dc.contributor.alternativeNameChin, Bum Sik-
dc.contributor.alternativeNameChoi, Suk Hoon-
dc.contributor.alternativeNameChoi, Jun Yong-
dc.contributor.alternativeNameChoi, Hee Kyoung-
dc.contributor.affiliatedAuthorHan, Sang Hoon-
dc.contributor.affiliatedAuthorKim, June Myung-
dc.contributor.affiliatedAuthorKim, Chang Ki-
dc.contributor.affiliatedAuthorKim, Chang Oh-
dc.contributor.affiliatedAuthorSong, Young Goo-
dc.contributor.affiliatedAuthorYong, Dong Eun-
dc.contributor.affiliatedAuthorLee, Kyung Won-
dc.contributor.affiliatedAuthorLee, Han Sung-
dc.contributor.affiliatedAuthorJeong, Su Jin-
dc.contributor.affiliatedAuthorCho, Cheong Ho-
dc.contributor.affiliatedAuthorChin, Bum Sik-
dc.contributor.affiliatedAuthorChoi, Suk Hoon-
dc.contributor.affiliatedAuthorChoi, Jun Yong-
dc.contributor.affiliatedAuthorChoi, Hee Kyoung-
dc.contributor.affiliatedAuthorKim, Myoung Soo-
dc.rights.accessRightsfree-
dc.citation.volume40-
dc.citation.number2-
dc.citation.startPage102-
dc.citation.endPage106-
dc.identifier.bibliographicCitationInfection and Chemotherapy (감염과 화학요법), Vol.40(2) : 102-106, 2008-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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