243 246

Cited 0 times in

Risk factors for adverse outcomes after peritonitis-related technique failure

DC FieldValueLanguage
dc.contributor.author강신욱-
dc.contributor.author김동기-
dc.contributor.author김범석-
dc.contributor.author문성진-
dc.contributor.author이정은-
dc.contributor.author이호영-
dc.contributor.author최규헌-
dc.contributor.author한대석-
dc.contributor.author한승혁-
dc.date.accessioned2015-05-19T16:38:42Z-
dc.date.available2015-05-19T16:38:42Z-
dc.date.issued2008-
dc.identifier.issn0896-8608-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/106681-
dc.description.abstractBACKGROUND: Peritonitis is the leading cause of technique failure in peritoneal dialysis (PD) patients. Some patients experience recurrent ascites, encapsulating peritoneal sclerosis (EPS), and even death after catheter removal. Little is known, however, about the risk factors for such complications. METHODS: The study subjects were 117 patients that had their PD catheter removed due to peritonitis between January 2000 and June 2006. Biochemical and clinical data were reviewed retrospectively. Serum C-reactive protein (CRP) and blood and effluent white blood cell counts (WBC) were measured at baseline and at 72 hours of peritonitis. Based on adverse outcomes, patients were classified into 4 groups: non-complication (NC; n = 73), recurrent ascites (A; n = 26), EPS (E; n = 10), and death directly related to peritonitis (D; n = 8). RESULTS: Age at PD catheter removal was significantly higher in D group compared to NC group (62.0 +/- 10.6 vs 51.2 +/- 11.5 years, p < 0.05). In addition, mean PD duration was significantly longer in E group compared to NC and A groups (130.5 +/- 48.1 vs 58.8 +/- 42.4 vs 74.8 +/- 47.4 months, p < 0.01). Compared to baseline, effluent WBC was significantly decreased in NC group after 72 hours of peritonitis. In addition, serum CRP level was significantly decreased in NC and A groups, whereas it was significantly increased in D group. Multivariate analyses adjusted for age, PD duration, blood and effluent WBC, serum CRP, and micro-organisms revealed that serum CRP level at 72 hours predicted significantly the development of EPS [odds ratio (OR) 1.15, p < 0.05] and peritonitis-related death (OR 1.18, p < 0.01). In addition, PD duration (per 1 month increase: OR 1.03, p < 0.05) and age at PD catheter removal (per 1 year increase: OR 1.11, p < 0.05) were identified as significant determinants of EPS and peritonitis-related death respectively. Only effluent WBC at 72 hours was significantly associated with the development of ascites (OR 1.27, p < 0.05). CONCLUSION: Older patients with long PD duration and those with persistently elevated serum CRP levels were likely to develop complications after peritonitis-related technique failure. Our study suggests that serial measurement of CRP may be helpful in predicting the development of complications after PD catheter removal.-
dc.description.statementOfResponsibilityopen-
dc.format.extent352~360-
dc.relation.isPartOfPERITONEAL DIALYSIS INTERNATIONAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAge Factors-
dc.subject.MESHC-Reactive Protein/analysis-
dc.subject.MESHC-Reactive Protein/metabolism*-
dc.subject.MESHCatheters, Indwelling/adverse effects*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHKidney Failure, Chronic/complications*-
dc.subject.MESHKidney Failure, Chronic/metabolism-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMultivariate Analysis-
dc.subject.MESHPeritoneal Dialysis/adverse effects*-
dc.subject.MESHPeritoneal Dialysis/instrumentation-
dc.subject.MESHPeritonitis/blood-
dc.subject.MESHPeritonitis/etiology*-
dc.subject.MESHPeritonitis/metabolism-
dc.subject.MESHPeritonitis/pathology-
dc.subject.MESHRecurrence-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Factors-
dc.subject.MESHSurvival Analysis-
dc.subject.MESHTreatment Outcome-
dc.titleRisk factors for adverse outcomes after peritonitis-related technique failure-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorSung Jin Moon-
dc.contributor.googleauthorSeung Hyeok Han-
dc.contributor.googleauthorDong Ki Kim-
dc.contributor.googleauthorJung Eun Lee-
dc.contributor.googleauthorBeom Seok Kim-
dc.contributor.googleauthorShin-Wook Kang-
dc.contributor.googleauthorKyu Hun Choi-
dc.contributor.googleauthorHo Yung Lee-
dc.contributor.googleauthorDae-Suk Han-
dc.identifier.doi18556377-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00053-
dc.contributor.localIdA00488-
dc.contributor.localIdA01364-
dc.contributor.localIdA03326-
dc.contributor.localIdA04043-
dc.contributor.localIdA04272-
dc.contributor.localIdA04304-
dc.contributor.localIdA03119-
dc.contributor.localIdA00400-
dc.relation.journalcodeJ02500-
dc.identifier.eissn1718-4304-
dc.identifier.pmid18556377-
dc.subject.keywordAdult-
dc.subject.keywordAge Factors-
dc.subject.keywordC-Reactive Protein/analysis-
dc.subject.keywordC-Reactive Protein/metabolism*-
dc.subject.keywordCatheters, Indwelling/adverse effects*-
dc.subject.keywordFemale-
dc.subject.keywordHumans-
dc.subject.keywordKidney Failure, Chronic/complications*-
dc.subject.keywordKidney Failure, Chronic/metabolism-
dc.subject.keywordMale-
dc.subject.keywordMiddle Aged-
dc.subject.keywordMultivariate Analysis-
dc.subject.keywordPeritoneal Dialysis/adverse effects*-
dc.subject.keywordPeritoneal Dialysis/instrumentation-
dc.subject.keywordPeritonitis/blood-
dc.subject.keywordPeritonitis/etiology*-
dc.subject.keywordPeritonitis/metabolism-
dc.subject.keywordPeritonitis/pathology-
dc.subject.keywordRecurrence-
dc.subject.keywordRetrospective Studies-
dc.subject.keywordRisk Factors-
dc.subject.keywordSurvival Analysis-
dc.subject.keywordTreatment Outcome-
dc.contributor.alternativeNameKang, Shin Wook-
dc.contributor.alternativeNameKim, Dong Ki-
dc.contributor.alternativeNameKim, Beom Seok-
dc.contributor.alternativeNameMoon, Sung Jin-
dc.contributor.alternativeNameLee, Jung Eun-
dc.contributor.alternativeNameLee, Ho Yung-
dc.contributor.alternativeNameChoi, Kyu Hun-
dc.contributor.alternativeNameHan, Dae Suk-
dc.contributor.alternativeNameHan, Seung Hyeok-
dc.contributor.affiliatedAuthorKang, Shin Wook-
dc.contributor.affiliatedAuthorKim, Beom Seok-
dc.contributor.affiliatedAuthorMoon, Sung Jin-
dc.contributor.affiliatedAuthorLee, Ho Yung-
dc.contributor.affiliatedAuthorChoi, Kyu Hun-
dc.contributor.affiliatedAuthorHan, Dae Suk-
dc.contributor.affiliatedAuthorHan, Seung Hyeok-
dc.contributor.affiliatedAuthorLee, Jung Eun-
dc.contributor.affiliatedAuthorKim, Dong Ki-
dc.rights.accessRightsfree-
dc.citation.volume28-
dc.citation.number4-
dc.citation.startPage352-
dc.citation.endPage360-
dc.identifier.bibliographicCitationPERITONEAL DIALYSIS INTERNATIONAL, Vol.28(4) : 352-360, 2008-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.