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Long-term clinical outcomes of peritoneal dialysis patients: single center experience from Korea

DC FieldValueLanguage
dc.contributor.author강신욱-
dc.contributor.author김동기-
dc.contributor.author김범석-
dc.contributor.author김현욱-
dc.contributor.author문성진-
dc.contributor.author이정은-
dc.contributor.author이호영-
dc.contributor.author장제현-
dc.contributor.author최규헌-
dc.contributor.author한대석-
dc.contributor.author한승혁-
dc.date.accessioned2015-05-19T16:38:23Z-
dc.date.available2015-05-19T16:38:23Z-
dc.date.issued2008-
dc.identifier.issn0896-8608-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/106672-
dc.description.abstractOf a large body of literature reporting clinical outcomes for patients maintained on peritoneal dialysis (PD), most publications have focused on relatively short-term results. Few reports have focused on long-term survival in PD patients. Here, we present our experience with long-term patient outcomes and further analyses of the trends in demographics and clinical outcomes of 2301 end-stage renal disease (ESRD) patients treated with continuous ambulatory PD (CAPD) during a 25-year period (1981 - 2005) at our institute. Outcomes were analyzed for 1656 patients, excluding those younger than 15 years of age at initiation of CAPD, those having less than 3 months' follow-up, or those who had been on hemodialysis or who received a kidney graft before starting CAPD. In the study patients, technique survival at 5 and 10 years was 71.9% and 48.1% respectively. Patient survival was 69.8% and 51.8%. Mean age at the start of PD (50.4 +/- 13.9 years vs. 44.2 +/- 13.9 years, p < 0.01), ESRD incidence as a result of diabetic nephropathy (30.5% vs. 19.5%, p < 0.01), and incidence of cardiovascular comorbidities (26.6% vs. 20.5%, p < 0.01) were all significantly greater in patients who started PD during the second half of the study period (1993 - 2005) as compared with the first half (1981 - 1992). A multivariate analysis adjusting for these changes in demographics and comorbid conditions revealed that PD therapy starting in 1993 - 2005 was associated with a significant reduction in technique failure [hazard ratio (HR): 0.65; p < 0.01] and mortality (HR: 0.68; p < 0.01) as compared with the earlier period. However, in subgroup analyses, technique survival was not observed to be significantly improved in patients with diabetes. In summary, technique and patient survival have significantly improved despite increases in patient age, cardiovascular comorbidity, and ESRD caused by diabetes. Although diabetes, older age, and cardiovascular comorbidities are not factors that are easily modifiable to improve PD outcomes, results at our institution are encouraging in an era of declining PD utilization.-
dc.description.statementOfResponsibilityopen-
dc.format.extentS21~S26-
dc.relation.isPartOfPERITONEAL DIALYSIS INTERNATIONAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHKidney Failure, Chronic/mortality-
dc.subject.MESHKidney Failure, Chronic/therapy-
dc.subject.MESHKorea/epidemiology-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHOutcome Assessment (Health Care)*-
dc.subject.MESHPeritoneal Dialysis, Continuous Ambulatory/mortality*-
dc.subject.MESHRisk Factors-
dc.subject.MESHSurvival Rate/trends-
dc.titleLong-term clinical outcomes of peritoneal dialysis patients: single center experience from Korea-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorSeung Hyeok Han-
dc.contributor.googleauthorJung Eun Lee-
dc.contributor.googleauthorDong Ki Kim-
dc.contributor.googleauthorSung Jin Moon-
dc.contributor.googleauthorHyun-Wook Kim-
dc.contributor.googleauthorJae Hyun Chang-
dc.contributor.googleauthorBeom Seok Kim-
dc.contributor.googleauthorShin-Wook Kang-
dc.contributor.googleauthorKyu Hun Choi-
dc.contributor.googleauthorHo Yung Lee-
dc.contributor.googleauthorDae Suk Han-
dc.identifier.doi18552258-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00053-
dc.contributor.localIdA00488-
dc.contributor.localIdA01126-
dc.contributor.localIdA01364-
dc.contributor.localIdA03326-
dc.contributor.localIdA03469-
dc.contributor.localIdA04043-
dc.contributor.localIdA04272-
dc.contributor.localIdA04304-
dc.contributor.localIdA03119-
dc.contributor.localIdA00400-
dc.relation.journalcodeJ02500-
dc.identifier.eissn1718-4304-
dc.identifier.pmid18552258-
dc.subject.keywordContinuous ambulatory peritoneal dialysis-
dc.subject.keywordpatient survival-
dc.subject.keywordtechnique survival-
dc.contributor.alternativeNameKang, Shin Wook-
dc.contributor.alternativeNameKim, Dong Ki-
dc.contributor.alternativeNameKim, Beom Seok-
dc.contributor.alternativeNameKim, Hyun Wook-
dc.contributor.alternativeNameMoon, Sung Jin-
dc.contributor.alternativeNameLee, Jung Eun-
dc.contributor.alternativeNameLee, Ho Yung-
dc.contributor.alternativeNameChang, Jae Hyun-
dc.contributor.alternativeNameChoi, Kyu Hun-
dc.contributor.alternativeNameHan, Dae Suk-
dc.contributor.alternativeNameHan, Seung Hyeok-
dc.contributor.affiliatedAuthorKang, Shin Wook-
dc.contributor.affiliatedAuthorKim, Beom Seok-
dc.contributor.affiliatedAuthorKim, Hyun Wook-
dc.contributor.affiliatedAuthorMoon, Sung Jin-
dc.contributor.affiliatedAuthorLee, Ho Yung-
dc.contributor.affiliatedAuthorChang, Jae Hyun-
dc.contributor.affiliatedAuthorChoi, Kyu Hun-
dc.contributor.affiliatedAuthorHan, Dae Suk-
dc.contributor.affiliatedAuthorHan, Seung Hyeok-
dc.contributor.affiliatedAuthorLee, Jung Eun-
dc.contributor.affiliatedAuthorKim, Dong Ki-
dc.rights.accessRightsfree-
dc.citation.volume28-
dc.citation.numbersuppl 3-
dc.citation.startPage21-
dc.citation.endPage26-
dc.identifier.bibliographicCitationPERITONEAL DIALYSIS INTERNATIONAL, Vol.28(suppl 3) : 21-26, 2008-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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