Cited 11 times in
Increased plasma aldosterone-to-renin ratio is associated with impaired left ventricular longitudinal functional reserve in patients with uncomplicated hypertension
DC Field | Value | Language |
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dc.contributor.author | 고영국 | - |
dc.contributor.author | 최동훈 | - |
dc.contributor.author | 박성하 | - |
dc.contributor.author | 최의영 | - |
dc.contributor.author | 서혜선 | - |
dc.contributor.author | 하종원 | - |
dc.contributor.author | 심지영 | - |
dc.contributor.author | 윤세정 | - |
dc.contributor.author | 임세중 | - |
dc.contributor.author | 장양수 | - |
dc.contributor.author | 강석민 | - |
dc.contributor.author | 정남식 | - |
dc.date.accessioned | 2015-05-19T16:36:28Z | - |
dc.date.available | 2015-05-19T16:36:28Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 0894-7317 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/106615 | - |
dc.description.abstract | Relative aldosterone excess is associated with endothelial dysfunction and higher incidence of end organ damage. We sought to investigate whether plasma aldosterone-to-renin ratio (ARR) is associated with left ventricular (LV) longitudinal function reserve to exercise in patients with controlled hypertension. In the patients with controlled and uncomplicated hypertension without overt LV hypertrophy, plasma aldosterone concentrations (ng/dL) and renin activities (ng/mL/h) were measured. Then 28 consecutive patients with higher ARR (group II, ARR > or = 30, 55 +/- 10 years) and 56 age- and sex-matched patients with lower ARR (group I, ARR < 30) underwent supine bicycle exercise echocardiography. Despite similar 24-hour blood pressure, LV mass index was significantly higher in group II (91.1 +/- 16.4 vs 101.7 +/- 18.2 g/m(2), P = .008). Early diastolic and systolic mitral annular velocity (E' and S', cm/s) at 50-W exercise was significantly lower in group II compared with group I (9.91 +/- 1.66 vs 8.67 +/- 1.65 cm/s, P = .002; 9.52 +/- 1.71 vs 8.46 +/- 1.79, P = .010, respectively) despite similar resting values. Longitudinal diastolic functional reserve at 25-W and 50-W exercise, defined as DeltaE' (change from resting E', cm/s) of group II was significantly lower than that of group I (2.60 +/- 1.42 vs 1.85 +/- 1.44 cm/s, P = .016; 3.40 +/- 1.48 vs 2.36 +/- 1.43 cm/s, P = .003, respectively). In conclusion, in patients with hypertension without overt LV hypertrophy, increased ARR is associated with increased LV mass, and impaired LV longitudinal functional reserve during exercise. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 251~256 | - |
dc.relation.isPartOf | JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Aldosterone/blood* | - |
dc.subject.MESH | Exercise Test | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Fractional FlowReserve, Myocardial* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hypertension/blood* | - |
dc.subject.MESH | Hypertension/complications | - |
dc.subject.MESH | Hypertension/diagnostic imaging* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Renin/blood* | - |
dc.subject.MESH | Ultrasonography | - |
dc.subject.MESH | VentricularDysfunction,Left/blood* | - |
dc.subject.MESH | VentricularDysfunction,Left/complications | - |
dc.subject.MESH | VentricularDysfunction,Left/diagnostic imaging* | - |
dc.title | Increased plasma aldosterone-to-renin ratio is associated with impaired left ventricular longitudinal functional reserve in patients with uncomplicated hypertension | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Eui-Young Choi | - |
dc.contributor.googleauthor | Jong-Won Ha | - |
dc.contributor.googleauthor | Se-Jung Yoon | - |
dc.contributor.googleauthor | Chi-Young Shim | - |
dc.contributor.googleauthor | Hye-Sun Seo | - |
dc.contributor.googleauthor | Sungha Park | - |
dc.contributor.googleauthor | Young-Guk Ko | - |
dc.contributor.googleauthor | Seok-Min Kang | - |
dc.contributor.googleauthor | Donghoon Choi | - |
dc.contributor.googleauthor | Se-Joong Rim | - |
dc.contributor.googleauthor | Yangsoo Jang | - |
dc.contributor.googleauthor | Namsik Chung | - |
dc.identifier.doi | 10.1016/j.echo.2007.08.005 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00127 | - |
dc.contributor.localId | A04053 | - |
dc.contributor.localId | A01512 | - |
dc.contributor.localId | A04165 | - |
dc.contributor.localId | A01923 | - |
dc.contributor.localId | A04257 | - |
dc.contributor.localId | A02213 | - |
dc.contributor.localId | A02569 | - |
dc.contributor.localId | A03372 | - |
dc.contributor.localId | A03448 | - |
dc.contributor.localId | A00037 | - |
dc.contributor.localId | A03585 | - |
dc.relation.journalcode | J01777 | - |
dc.identifier.eissn | 1097-6795 | - |
dc.identifier.pmid | 17869062 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0894731707006116 | - |
dc.subject.keyword | Aldosterone/blood* | - |
dc.subject.keyword | Exercise Test | - |
dc.subject.keyword | Female | - |
dc.subject.keyword | Fractional FlowReserve, Myocardial* | - |
dc.subject.keyword | Humans | - |
dc.subject.keyword | Hypertension/blood* | - |
dc.subject.keyword | Hypertension/complications | - |
dc.subject.keyword | Hypertension/diagnostic imaging* | - |
dc.subject.keyword | Male | - |
dc.subject.keyword | Middle Aged | - |
dc.subject.keyword | Renin/blood* | - |
dc.subject.keyword | Ultrasonography | - |
dc.subject.keyword | VentricularDysfunction,Left/blood* | - |
dc.subject.keyword | VentricularDysfunction,Left/complications | - |
dc.subject.keyword | VentricularDysfunction,Left/diagnostic imaging* | - |
dc.contributor.alternativeName | Ko, Young Guk | - |
dc.contributor.alternativeName | Choi, Dong Hoon | - |
dc.contributor.alternativeName | Park, Sung Ha | - |
dc.contributor.alternativeName | Choi, Eui Young | - |
dc.contributor.alternativeName | Seo, Hye Sun | - |
dc.contributor.alternativeName | Ha, Jong Won | - |
dc.contributor.alternativeName | Shim, Chi Young | - |
dc.contributor.alternativeName | Yoon, Se Jung | - |
dc.contributor.alternativeName | Rim, Se Joong | - |
dc.contributor.alternativeName | Jang, Yang Soo | - |
dc.contributor.alternativeName | Kang, Seok Min | - |
dc.contributor.alternativeName | Chung, Nam Sik | - |
dc.contributor.affiliatedAuthor | Ko, Young Guk | - |
dc.contributor.affiliatedAuthor | Choi, Dong Hoon | - |
dc.contributor.affiliatedAuthor | Park, Sung Ha | - |
dc.contributor.affiliatedAuthor | Choi, Eui Young | - |
dc.contributor.affiliatedAuthor | Seo, Hye Sun | - |
dc.contributor.affiliatedAuthor | Ha, Jong Won | - |
dc.contributor.affiliatedAuthor | Shim, Chi Young | - |
dc.contributor.affiliatedAuthor | Yoon, Se Jung | - |
dc.contributor.affiliatedAuthor | Rim, Se Joong | - |
dc.contributor.affiliatedAuthor | Jang, Yang Soo | - |
dc.contributor.affiliatedAuthor | Kang, Seok Min | - |
dc.contributor.affiliatedAuthor | Chung, Nam Sik | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 21 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 251 | - |
dc.citation.endPage | 256 | - |
dc.identifier.bibliographicCitation | JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY, Vol.21(3) : 251-256, 2008 | - |
dc.identifier.rimsid | 46147 | - |
dc.type.rims | ART | - |
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